List of the Top 7 Cybersecurity Software for Microsoft Defender for Endpoint in 2025

Combining comprehensive response skills with real-time threat insights from more than 3,000 incidents managed annually and extensive knowledge in cybersecurity, we safeguard against, identify, and react to cyber threats.

Axonius empowers IT and security teams to effectively manage complexity by serving as a definitive repository for their entire digital infrastructure. By offering a detailed insight into all assets, such as devices, identities, software, SaaS applications, vulnerabilities, and security measures, clients can proactively address threats, assess risks, reduce response times to incidents, automate processes, and guide strategic business decisions, all while minimizing the burden of repetitive manual work. This capability not only streamlines operations but also enhances overall security posture.

SOC Prime provides security teams with a comprehensive and powerful platform for collaborative cyber defense, fostering teamwork among a worldwide cybersecurity community while offering the latest Sigma rules that are compatible with more than 28 SIEM, EDR, and XDR platforms. By utilizing a zero-trust framework and innovative technology derived from Sigma and MITRE ATT&CK®️, SOC Prime facilitates intelligent data orchestration, economically efficient threat hunting, and adaptive attack surface visibility, thereby enhancing the return on investment for SIEM, EDR, XDR, and Data Lake solutions while improving detection engineering productivity. The company’s groundbreaking advancements have garnered recognition from independent research firms, endorsements from top SIEM, XDR, and MDR vendors, and the trust of over 8,000 organizations across 155 countries, including notable percentages of Fortune 100 companies, Forbes Global 2000 firms, public sector institutions, and numerous MSSP and MDR providers. Supported by notable investors such as DNX Ventures, Streamlined Ventures, and Rembrandt Venture Partners, SOC Prime successfully raised $11.5 million in funding in October 2021. Through its cutting-edge cybersecurity offerings, including the Threat Detection Marketplace, Uncoder AI, and Attack Detective, SOC Prime empowers organizations to enhance their cybersecurity strategies and effectively manage risk. This commitment to innovation and collaboration positions SOC Prime as a leader in the evolving landscape of cybersecurity.

Armis, a premier company specializing in asset visibility and security, offers a comprehensive asset intelligence platform that tackles the challenges posed by the increasingly complex attack surface created by interconnected assets. Renowned Fortune 100 companies rely on our continuous and real-time safeguarding to gain complete insight into all managed and unmanaged assets spanning IT, cloud environments, IoT devices, IoMT, operational technology, industrial control systems, and 5G networks. Our solutions include passive cyber asset management, risk assessment, and automated policy enforcement to enhance security. Based in California, Armis operates as a privately held enterprise dedicated to ensuring robust protection for diverse asset ecosystems. Our commitment to innovation positions us as a trusted partner in the ever-evolving landscape of cybersecurity.

Picus Security stands at the forefront of security validation, enabling organizations to gain a comprehensive understanding of their cyber risks within a business framework. By effectively correlating, prioritizing, and validating disparate findings, Picus aids teams in identifying critical vulnerabilities and implementing significant solutions. With the convenience of one-click mitigations, security teams can swiftly respond to threats with greater efficiency and reduced effort. The Picus Security Validation Platform integrates smoothly across on-premises setups, hybrid clouds, and endpoint devices, utilizing Numi AI to ensure accurate exposure validation. As a trailblazer in Breach and Attack Simulation, Picus offers award-winning, threat-centric technology that allows teams to concentrate on the most impactful fixes. Its proven effectiveness is underscored by a remarkable 95% recommendation rate on Gartner Peer Insights, reflecting its value in enhancing cybersecurity measures for organizations. This recognition further solidifies Picus's position as a trusted partner in navigating the complex landscape of cybersecurity challenges.

Panaseer's continuous control monitoring platform serves as a robust solution for overseeing every facet of your organization. It delivers reliable, automated insights regarding the organization's security and risk posture. By establishing a comprehensive inventory of all organizational elements—such as devices, applications, personnel, accounts, and databases—the platform pinpoints assets that may be absent from various sources and highlights potential security vulnerabilities. Furthermore, it offers valuable metrics and assessments to help you comprehend your compliance and security standing at all levels. The platform is capable of processing data from any source, whether it's cloud-based or on-premises, allowing for flexibility in data integration. Users can easily access this information across security, IT, and business domains through readily available data connectors. By employing entity resolution techniques, the platform effectively cleans, normalizes, aggregates, and de-duplicates the data, resulting in a continuous stream of insights regarding unified assets and controls across devices, applications, personnel, databases, and accounts. This ensures that organizations can maintain a proactive approach to their security and compliance needs.

Leverage ContraForce to optimize investigation processes across diverse tenants, automate the handling of security incidents, and deliver exceptional managed security services. Attain cost efficiency through scalable pricing models while maintaining high performance customized to your operational needs. By enhancing the speed and scope of your existing Microsoft security infrastructure with robust workflows and integrated security engineering tools, you can take full advantage of advanced multi-tenancy features. Experience the benefits of automated responses that adapt to your business's context, ensuring comprehensive protection for your clients from endpoints to the cloud, all achieved without the complexities of scripting, agents, or coding. Manage multiple Microsoft Defender and Sentinel customer accounts, along with incidents and cases from other XDR, SIEM, and ticketing platforms, from a centralized location. Enjoy a streamlined investigation hub where all security alerts and data can be accessed in one cohesive platform. With ContraForce, you can effectively conduct threat detection, investigations, and response workflows within a unified framework, significantly improving the efficiency and effectiveness of your security operations while keeping pace with evolving threats. This consolidated approach not only enhances response times but also fortifies the overall security posture of your organization.