List of the Top 14 On-Prem HIPAA Compliance Software in 2025

Safetica Intelligent Data Security ensures the protection of sensitive enterprise information no matter where your team operates. This international software organization specializes in providing solutions for Data Loss Prevention and Insider Risk Management to various businesses. ✔️ Identify what needs safeguarding: Effectively detect personally identifiable information, intellectual property, financial details, and more, no matter where they are accessed within the organization, cloud, or on endpoint devices. ✔️ Mitigate risks: Recognize and respond to dangerous behaviors by automatically detecting unusual file access, email interactions, and online activities, receiving alerts that help in proactively managing threats and avoiding data breaches. ✔️ Protect your information: Prevent unauthorized access to sensitive personal data, proprietary information, and intellectual assets. ✔️ Enhance productivity: Support teams with live data management hints that assist them while accessing and sharing confidential information. Additionally, implementing such robust security measures can foster a culture of accountability and awareness among employees regarding data protection.

StandardFusion offers a comprehensive Governance, Risk, and Compliance (GRC) solution tailored for technology-driven small and medium-sized businesses as well as enterprise information security teams. By consolidating all data into a single system of record, it removes the reliance on spreadsheets, enabling users to confidently identify, evaluate, manage, and monitor risks. The platform establishes audit-based processes as a standard practice, allowing for streamlined audits with straightforward access to necessary evidence. Organizations can effectively manage compliance across various standards, including ISO, SOC, NIST, HIPAA, GDPR, PCI-DSS, and FedRAMP. Furthermore, it provides a centralized location for handling all vendor and third-party risk assessments and security questionnaires. As either a cloud-based SaaS solution or an on-premise GRC platform, StandardFusion is designed to simplify information security compliance, making it both accessible and scalable to fit a company's evolving needs. This unified approach not only enhances efficiency but also strengthens overall security posture.

Whether you're utilizing a desktop setup, a multifunction printer (MFP), or managing tasks on a mobile device, eGoldFax offers seamless fax communication that redefines convenience. Experience the endless possibilities that eGoldFax brings, allowing you to effortlessly reroute incoming faxes to your chosen destination—be it an email, a network folder, or a specific printer—granting you unparalleled flexibility to manage your faxes according to your individual workflow preferences. eGoldFax is compatible with leading Multi-Function Product manufacturers such as Sharp, Kyocera, Xerox, Konica Minolta, Canon, HP, Ricoh, Lexmark, and others, with an API available for those needing advanced workflow solutions. Beyond transforming the faxing process, eGoldFax also supports organizations in meeting compliance requirements for various regulatory standards, including HIPAA, GDPR, PCI, and FERPA. Join a multitude of satisfied clients who rely on eGoldFax to protect their confidential data while ensuring compliance with essential industry regulations, thus enhancing the overall integrity of their operations.

SecPod SanerNow stands out as a premier unified platform for endpoint security and management, empowering IT and security teams to streamline and automate essential cyber hygiene processes. Utilizing a sophisticated agent-server framework, it guarantees robust endpoint security alongside efficient management capabilities. The platform excels in vulnerability management by providing comprehensive scanning, detection, assessment, and prioritization features. Available for both on-premise and cloud deployment, SanerNow seamlessly integrates with patch management systems to facilitate automatic updates across major operating systems like Windows, macOS, and Linux, as well as numerous third-party software applications. What truly sets it apart is its expansion into additional critical functionalities, which include security compliance management and IT asset tracking. Moreover, users can leverage capabilities for software deployment, device control, and endpoint threat detection and response. All of these operations can be conducted remotely and automated, reinforcing defenses against the evolving threats posed by modern cyberattacks. This versatile platform not only enhances security but also simplifies the management of IT assets, making it an invaluable tool for organizations of all sizes.

SaltStack serves as an advanced IT automation platform capable of managing, securing, and enhancing infrastructure across various environments, whether on-premises, in the cloud, or at the edge. It operates on an event-driven automation engine that intelligently identifies and reacts to system changes, which proves invaluable in handling intricate settings. This robust framework is especially useful in addressing the complexities of modern IT landscapes. The latest addition to SaltStack's offerings is its SecOps suite, designed to identify security vulnerabilities and misconfigurations within systems. With this advanced automation, issues can be promptly detected and rectified, ensuring that your infrastructure remains secure, compliant, and continuously updated. Within the SecOps suite, the components Comply and Protect play crucial roles. Comply is responsible for checking compliance against standards such as CIS, DISA, STIG, NIST, and PCI. Additionally, it assesses operating systems for vulnerabilities and facilitates the updating of patches to bolster security measures effectively. This comprehensive approach not only enhances security but also simplifies the management of compliance requirements.

Abyde offers a straightforward design for HIPAA compliance that is user-friendly and packed with top-notch features. With the support of their HIPAA experts, you can confidently navigate the audit process. Their cloud-based solution, accessible from anywhere, removes the hassle of cumbersome HIPAA manuals. You can also receive personalized policies tailored to your specific practice needs, covering all essential areas. Abyde’s user-friendly application streamlines the complexities associated with HIPAA compliance, incorporating features like straightforward notifications and conditional questions that enhance overall efficiency. Additionally, Abyde’s automated risk analysis enables you to swiftly fulfill MIPS or MACRA incentive requirements, while simultaneously providing valuable education to your practice. This comprehensive approach ensures that you are well-equipped to handle compliance challenges.

The interactions among members of the care team involve a complex web of individuals, technology, hospital systems, and devices. Navigating an extensive flow of information, encountering communication barriers, or facing inefficient processes can complicate your role and adversely affect patient care. Such challenges can hinder your efficiency and ultimately lead to poorer health outcomes for patients. Spok Care Connect® offers a comprehensive solution to these issues. This integrated communication platform enhances collaboration among care teams, facilitates closed-loop communication, and ensures secure messaging, all aimed at optimizing clinical workflows. By utilizing a single communication platform, various challenges across multiple departments and locations within a healthcare system can be effectively addressed, leading to improved operational efficiency and better patient care.

AD360 is a comprehensive identity management solution that oversees user identities, regulates resource access, enforces security measures, and guarantees compliance with regulations. With its user-friendly interface, AD360 simplifies the execution of all IAM tasks. This solution is compatible with Windows Active Directory, Exchange Servers, and Office 365, providing a versatile platform for managing identities. Users can select from various modules tailored to their needs, facilitating the resolution of IAM challenges across hybrid, on-premises, and cloud environments. From a single console, you can efficiently provision, modify, and deprovision accounts and mailboxes for numerous users simultaneously. This capability extends to managing accounts across Exchange servers, Office 365, and G Suite. Additionally, the platform supports bulk provisioning of user accounts by utilizing customizable templates for user creation and allows for easy data import from CSV files, making the process even more streamlined. Overall, AD360 is designed to enhance productivity and security in identity management.

Runecast is a comprehensive IT solution designed for enterprises that helps Security and Operations teams optimize their time and resources by facilitating a forward-thinking strategy for IT operations management, cloud security posture management, and compliance. With this all-in-one platform, your team can enhance their efficiency and effectiveness while managing all aspects of your cloud infrastructure, resulting in greater visibility, improved security measures, and significant time savings. Security personnel experience streamlined vulnerability management and adherence to various compliance standards, covering a wide range of technologies. Meanwhile, Operations teams can minimize their operational costs and gain better clarity, empowering them to adopt a proactive stance and focus on the essential tasks that truly matter to your organization. This holistic approach not only supports team productivity but also strengthens your overall IT ecosystem.

Enterprise File Fabric™ is a secure and private multi-cloud content collaboration platform governed by policies, designed to optimize the storage, sharing, and teamwork experience among users. It does not come with built-in storage but seamlessly integrates with any organization’s existing storage solutions, whether they are on the cloud or hosted on-site. By unifying and securing various storage types, including object storage, Enterprise File Fabric™ ensures easy accessibility for end-users. Additionally, the Enterprise File Fabric for Compliance offers three distinct product variations: the first focuses on enforcing regulations like GDPR, CCPA, and HIPAA through intelligent policy-based measures for all corporate data; the second variation, tailored for the Media and Entertainment sector, provides a comprehensive view of media assets that can be shared both on-cloud and locally, enhancing collaboration across the industry. Furthermore, this platform's adaptability allows businesses to streamline their workflows while maintaining compliance and security.

A comprehensive digital command hub designed to manage the auditing necessities of ISO 27001:2013 and ISO 9001:2015, specifically focusing on sections 4-10, along with all pertinent GRC compliance requirements, both legal and contractual, is paramount for modern organizations. The ISO Manager for ISO 27001:2013 and ISO 9001:2015 is recognized as one of the most intuitive management software solutions available worldwide. Proven through numerous implementations, the ISO Manager Cloud SaaS is appropriate for businesses of all sizes. Leveraging our distinctive ISO 27001 framework, it offers a clear, step-by-step approach for executing and overseeing the fundamental requirements detailed in sections 4-10 of ISO 27001. Task management, often seen as a daunting element of ISO 27001 compliance, is simplified through our software, which organizes tasks into a user-friendly calendar-based system that enhances compliance and promotes effective time management. It includes all essential tools to efficiently implement, certify, and manage ISO 27001:2013 and ISO 9001:2015. Moreover, users are provided with a free ISO 27001 toolkit containing resources in MS Word and Excel formats, further easing the process. This thorough strategy guarantees that organizations can traverse the intricacies of ISO standards with confidence and simplicity, ultimately strengthening their compliance posture. Additionally, the software's user-centric design ensures that even those with limited technical expertise can navigate its features seamlessly.

SylLab Systems provides embedded compliance solutions specifically crafted for securing enterprise data, tackling the intricate issues tied to privacy compliance and cybersecurity, which can often result in high costs and complexities for organizations. Many businesses find it challenging to adhere to privacy regulations such as HIPAA, GDPR, PDPA, and CCPA, which can lead to significant financial burdens from necessary changes in architecture, legal advice, and consulting services. As privacy regulations continuously evolve and reach beyond current IT structures, the process of adapting to these shifts can be both an expensive and time-consuming endeavor, necessitating advanced legal and technical expertise. Fortunately, there is a more efficient and organized approach to handling data governance that can seamlessly fit into your complex IT environment, regardless of whether it resides in the cloud or on local servers. By gaining control over your compliance procedures and customizing them to suit your organizational goals, you can enhance operational efficiency significantly. Moreover, many leading financial institutions around the globe have trusted this solution, and you are invited to request a demo to delve deeper into its functionalities. By embracing this innovative compliance solution, you can confidently navigate the future with greater ease and assurance.

The realm of cybersecurity and data privacy compliance has transitioned into a continual endeavor, marking a departure from more straightforward times. Rizkly stands out as a vital resource for businesses aiming to adeptly manage these growing expectations while also pursuing their expansion goals. Equipped with a sophisticated platform and extensive experience, Rizkly helps you stay proactive regarding compliance obligations, providing specialized assistance to ensure adherence to EU privacy laws in a timely manner. By effectively protecting healthcare data, you can adopt a quicker and more economical strategy for privacy management and cyber hygiene. Furthermore, our service includes a prioritized action plan for PCI compliance, with the option to have an expert guide your project to maintain adherence to deadlines. Utilize our 20 years of expertise in SOC audits and assessments to accelerate your compliance journey. Rizkly functions as your OSCAL compliance automation platform, allowing for the smooth importation of your current FedRAMP SSP, thus relieving you from the tedious task of modifying Word documents. This strategic model positions Rizkly as a streamlined pathway to achieving FedRAMP authorization while ensuring ongoing supervision. Ultimately, with Rizkly, your organization can navigate the complexities of compliance with assurance and transparency, allowing you to focus on your core business objectives. Moreover, the integration of Rizkly’s solutions fosters a culture of proactive compliance, empowering your team to prioritize security alongside innovation.

An all-encompassing Data Governance platform delivers valuable insights that help in making informed decisions related to data reduction, compliance with regulations, and the shift to cloud services. Classify360 empowers businesses to oversee their redundant, obsolete, and trivial (ROT) data, as well as personally identifiable information (PII) and data associated with risks, by applying policies that ensure adherence to regulations and promote data minimization, which leads to a reduced data footprint and smoother transitions to cloud environments. Discover a unified index that presents a comprehensive overview of your organization’s data, sourced from a variety of growing datasets. By identifying data at its origin, organizations can decrease the costs, complexities, and risks linked to managing multiple copies of data. Additionally, this solution allows for the detection of data at a petabyte scale across both on-premises and cloud data storage, guaranteeing effective resource management and utilization. This functionality not only strengthens data governance but also fosters a more robust overall data strategy, ultimately driving better decision-making and operational efficiency. As businesses continue to navigate the complexities of data management, leveraging such a platform becomes increasingly essential for maintaining competitive advantage.