List of the Top 6 HIPAA Compliant Messaging Software for NextGen Healthcare EHR in 2025

Medsender offers a comprehensive automation solution for healthcare, featuring HIPAA-compliant faxing, emails, SMS, forms, and signatures, all effortlessly integrated into your electronic medical records (EMR) system. Utilizing cutting-edge artificial intelligence, it streamlines processes by securely managing incoming faxes through a cloud platform that sorts them automatically to the appropriate staff and patient charts. Patients benefit from an easy-to-use interface for filling out forms and sending notes, further enhancing communication and efficiency. With a simple one-click setup, there's no need for traditional fax machines, and Medsender's compatibility with all major EMRs, along with ongoing integration developments, ensures flexibility. Additionally, it can function independently of an EMR, allowing for versatile usage across various healthcare environments. By leveraging the latest AI advancements, we help you minimize repetitive tasks and unnecessary busy work, providing peace of mind. Currently, Medsender successfully handles over 5 million pages of patient data while maintaining an impressive uptime of over 99.9%. This commitment to reliability and efficiency makes Medsender an invaluable asset for healthcare providers seeking to enhance their operational workflows.

The interactions among members of the care team involve a complex web of individuals, technology, hospital systems, and devices. Navigating an extensive flow of information, encountering communication barriers, or facing inefficient processes can complicate your role and adversely affect patient care. Such challenges can hinder your efficiency and ultimately lead to poorer health outcomes for patients. Spok Care Connect® offers a comprehensive solution to these issues. This integrated communication platform enhances collaboration among care teams, facilitates closed-loop communication, and ensures secure messaging, all aimed at optimizing clinical workflows. By utilizing a single communication platform, various challenges across multiple departments and locations within a healthcare system can be effectively addressed, leading to improved operational efficiency and better patient care.

QliqCHAT Secure Texting serves as a real-time, secure communication platform that adheres to HIPAA regulations, enabling seamless interaction among all members of a healthcare team and fostering effective collaboration centered around patient care. This platform effectively eliminates the communication barriers that exist between physicians, nurses, patients, and caregivers. Developed by QliqSOFT, this innovative multimodal healthcare communication and automation platform integrates personnel and technology across both in-person and digital care settings. The user-friendly and customizable nature of the platform not only optimizes administrative workflows but also improves patient interaction by featuring smooth EHR integration, conversational AI capabilities, and language translation services. For over ten years, QliqSOFT has empowered healthcare institutions to maintain real-time, HIPAA-compliant communication among medical professionals and patients, while also automating standard clinical tasks that alleviate the workload on staff and transform their work processes. With their solutions, QliqSOFT has enabled more than 1,000 healthcare organizations to achieve substantial returns on their investments, ultimately enhancing the overall efficiency and effectiveness of healthcare delivery systems. By continuing to innovate and adapt, QliqSOFT remains committed to improving healthcare communication and patient outcomes.

Luma Health was established with the vision that the healthcare system should be more efficient and beneficial for every patient. The Patient Success Platform™ developed by Luma aims to integrate patient engagement efforts, ensuring that individuals remain connected to their healthcare providers throughout their entire medical experience, encompassing access, operations, clinical aspects, and financial considerations. This seamless integration is enhanced by Luma Bedrock™, which utilizes data-driven best practices derived from over 700 million data points collected from more than 80 million patient engagements. Currently, Luma caters to over 600 health systems, integrated delivery networks, federally qualified health centers, specialty networks, and clinics across the United States, effectively managing the care pathways of more than 50 million patients. As a result, Luma Health plays a crucial role in transforming how patients interact with and navigate the healthcare landscape.

Artera, a leader in SaaS for digital health, revolutionizes the patient experience with AI-powered virtual agents (available in both voice and text) that enhance every stage of the patient journey. Trusted by over 900 provider organizations—including specialty groups, FQHCs, major IDNs, and federal agencies—Artera engages with 100 million patients each year. Designed to support front desk teams, these virtual agents streamline patient access tasks such as self-scheduling, intake, forms, billing, and more. Whether complementing your staff or enabling a fully autonomous digital workforce, Artera provides customizable virtual agent solutions tailored to meet healthcare organizations at any stage of their AI adoption. Facilitating 2 billion communications in 109 languages across voice, text, and web, Artera combines a decade of healthcare expertise with the power of AI to drive better outcomes.

Klara presents an all-encompassing platform that seamlessly merges secure messaging, remote monitoring, and video consultations to improve communication between patients and healthcare providers. This powerful system unifies various patient workflows into a single, streamlined interface, automating key interactions and optimizing appointment processes, which collectively contribute to an exceptional patient experience. By facilitating remote connections through secure messaging and video calls, Klara ensures that patients do not need to log in, check emails, or download applications, thus providing a simple and efficient environment. Both new and returning patients can easily reach out to staff directly via the website, which promotes higher appointment bookings and fosters ongoing patient engagement at any time. Moreover, the platform allows for the digitization of forms, enabling patients to fill them out on their personal devices while receiving timely text notifications for prompt signing. In addition, messages are organized into shared inboxes, permitting multiple team members to efficiently handle inquiries and manage their specific responsibilities, which significantly enhances collaboration among staff and elevates the quality of patient care. With its innovative features, Klara not only simplifies communication but also empowers healthcare teams to focus more on patient needs and improve service delivery.