List of the Top 5 Laboratory Information Systems (LIS) for Linux in 2025

The Avalon Laboratory System is an advanced and HIPAA-compliant platform tailored to oversee the production and billing needs of clinical, esoteric, and toxicology laboratories. Developed by Computer Service & Support (CSS), this modular laboratory information system provides a comprehensive suite of features aimed at automating reference laboratories. Additionally, it encompasses various modules for areas such as microbiology, pain management, toxicology, scheduling, remote laboratory operations, SQL access, and electronic medical records management. Beyond these functionalities, the system also integrates pharmacogenomics and revenue cycle management capabilities, making it a robust solution for modern laboratory challenges. This multifaceted approach ensures that labs can operate efficiently while adhering to regulatory standards.

Introducing an economical cloud-based Laboratory Information System (LIS) that's ideal for emerging laboratories! Subscriptions begin at just $250 a month, which includes three analyzer interfaces and unlimited user access. Our suite ensures CLIA compliance, simplifying adherence to regulatory standards. The user-friendly application can be set up within a day, and web-based training is readily available to assist users. This LIS is customizable to suit your specific analyzer and workflow needs. Additionally, our HIPAA-compliant mobile application facilitates patient registration, test ordering, and results notification. Our diverse clientele includes a variety of medical specialists and practice types, such as: My Doctor, LLC in Ohio, our inaugural client, a family practice; ABC Pediatrics in North Carolina, a pediatric clinic with ten physicians; Auspicious Lab in Texas, a toxicology commercial lab; Battelle Institute in Ohio, an applied science research facility; Children’s Healthcare of Atlanta in Georgia, where we link ten remote clinics to the main hospital system; Columbus LTACH in New Jersey, a hospital lab operating 26 analyzers; and the National Clinical Pathology Lab in Arkansas, the largest laboratory under the Federal Drug Administration. Furthermore, we proudly serve Next Oncology across the United States, a national chain focused on oncology and clinical trials.

SurroundLab™ Plus is an incredibly versatile and feature-laden laboratory information system designed specifically for the commercial sector. This groundbreaking platform allows you to deliver the personalized experience that your customers truly deserve. The system's extensive customization capabilities for report generation tailored to client specifications, along with its adaptability in terms of delivery schedules and methods, represent just a few of the many benefits SurroundLab Plus offers to both laboratories and their clients. Seacoast recognizes that each client presents a unique business challenge, and SurroundLab Plus is purposefully designed to enable you to align your operations with your individual objectives. It boasts advanced functionalities such as Master Patient ID, rules-based automated duplicate detection, and cutting-edge order processing logic. Furthermore, the system features ABN checking and printing, alerts for patient balances, and Easy Pay options to streamline the upfront collection of patient credit card payments. You have the capability to quickly receive HL7 inbound orders, implement 2-D barcode scanning for Lab Connect Orders, and produce bar-coded specimen labels. Additionally, custom algorithms for interpreting complex results equip your laboratory to effectively address a wide range of client requirements. In conclusion, SurroundLab Plus not only enhances operational efficiency but also significantly boosts client satisfaction by providing unmatched customization and control over laboratory operations, thus reinforcing its value in the market.

Established in 1987, Comtron Inc. has been delivering top-notch software solutions, drawing on significant expertise within the medical sector to effectively address contemporary challenges faced by healthcare professionals. Our diverse range of reliable applications is perfectly suited for practices and laboratories of varying scales, catering to both large multi-provider organizations and individual practitioners alike. This flexibility ensures that we can meet the unique needs of any healthcare provider in today’s fast-evolving medical landscape.

HORIZON stands out as one of the top 10 LIMS software options due to its design by lab managers and its affordability, making it adaptable for any laboratory setting. It is critical to recognize that a laboratory information management system should never be an afterthought due to its vital role in operational efficiency. HORIZON provides a superior alternative, crafted specifically with user needs in mind. Its ability to integrate effortlessly with current systems allows for customization that fits seamlessly into existing workflows, ensuring minimal disruption during adoption. Furthermore, HORIZON delivers immediate results, supported by a team of problem solvers who enhance its user-friendly interface. Developed by professionals with firsthand lab experience, HORIZON is attuned to the essential requirements for delivering accurate outcomes. Additionally, the platform is backed by expert support and implementation teams dedicated to ensuring that your system remains efficient and effective well into the future, reinforcing HORIZON's status in the competitive LIMS market. This commitment to user satisfaction and operational excellence is what truly sets HORIZON apart from its competitors.