List of the Top 6 On-Prem Pharmaceutical Manufacturing Software in 2025

The Asset Guardian (TAG) Mobi is the chosen preventive maintenance and asset management solution (EAM) for Microsoft Dynamics 365 Business Central, designed to deliver reliable manufacturing asset solutions that reduce risk and downtime. TAG Mobi prevent downtime, maximize asset performance, and accelerate onboarding and training with the support of AI tools and intuitive dashboards. No silos. No extra software. Just smooth integration and quick adoption—so maintenance teams can work faster, and managers get the data they need to make decisions.

QT9 ERP is a comprehensive platform designed for businesses seeking unlimited scalability and integration across various functions. This solution effectively combines real-time analytics, allowing organizations to streamline their manufacturing, sales, inventory, purchasing, and financial management processes. With over 18 interconnected modules, users can efficiently handle tasks such as Bill of Materials, Accounting, Sales Orders, Shipping, Invoicing, Inventory Control, Manufacturing, Purchasing, Inspections, and Job Scheduling within a single platform. The system enhances digital workflows by incorporating FDA 21 CFR Part 11 compliant electronic signatures, electronic batch records, design history records, email notifications, and customizable dashboard views. Additionally, it offers features such as lot and serial number traceability, ensuring that every aspect of production is meticulously tracked. By integrating quality management systems, QT9 ERP supports compliance with regulatory standards, making it especially useful for industries like Life Sciences, Medical Device Manufacturing, Pharmaceuticals, and Biotech. The platform also includes a Compliance Portal for auditors, expiring inventory alerts, and barcoding capabilities to optimize inventory management. Experience the benefits firsthand with a free product tour and a 30-day trial by visiting QT9erp.com today!

BatchMaster Manufacturing ERP Solutions is designed for formula-driven process manufacturers across various sectors, including Food, Chemical, Nutraceutical, and Life Sciences. The software encompasses a wide range of functionalities such as batch production, formulation management, packaging oversight, quality control, recall management, lot traceability, compliance with industry standards, and efficient planning and scheduling, along with mobile warehousing to enhance operational effectiveness. Additionally, manufacturers can seamlessly integrate their current financial systems, such as QuickBooks, Sage 100 & 300, and Microsoft Dynamics GP, to operate our process manufacturing application. Our ERP offering is ideal for businesses seeking to upgrade or replace their existing systems, as it addresses the specific needs of manufacturing, financial management, sales, supply chain logistics, purchasing, and customer service. We provide flexible deployment options for our applications, available both as on-premise purchases and as cloud-based solutions through monthly subscription plans, ensuring that manufacturers can choose what best fits their needs. This versatility allows companies to adapt their operations while benefiting from the comprehensive support that our ERP solutions provide.

The AssurX platform serves as an advanced software solution for enterprise quality management (EQMS) and regulatory compliance, enabling effective communication and coordination of information, documentation, and activities. By utilizing AssurX, regulated organizations can swiftly pinpoint and manage quality concerns and risk factors, thereby preventing issues related to quality or compliance while also enhancing workflow efficiency. The QMS software from AssurX is specifically designed to be customizable, accommodating both stable and evolving business needs. It establishes a digital workflow encompassing tasks, alerts, escalations, and approvals, which can be automated according to specific requirements, accurately reflecting real-world processes. There is no other system that matches its ease of deployment, configuration, and adaptability, making it a standout choice for businesses. In addition, AssurX solutions work together seamlessly to form an interconnected quality management system. These offerings include features such as audit management, corrective actions, training management, complaint management, document management, change control, risk management, and EHS incident management, among others, ensuring comprehensive coverage of quality management needs. Ultimately, the integration of these solutions supports organizations in achieving higher standards of quality and compliance across their operations.

TrendMiner is a cutting-edge analytics platform tailored for industrial applications, known for its speed, strength, and user-friendliness. This platform is specifically built to facilitate real-time monitoring and troubleshooting of industrial processes. By enabling comprehensive data collection, analysis, and visualization, it empowers individuals within industrial sectors to make informed, data-driven choices with enhanced efficiency. Founded in 2008, TrendMiner operates as a subsidiary of Proemion and maintains its global headquarters in Belgium, with additional offices situated in the U.S.A., Germany, Spain, and the Netherlands. The company has forged strategic partnerships with industry giants such as Amazon, Microsoft, and SAP, enhancing its market presence. Furthermore, TrendMiner provides standard integrations for a wide range of data historians, including well-known systems like Honeywell PHD and GE Proficy Historian, ensuring seamless compatibility and functionality across various platforms. This extensive network of connections highlights TrendMiner's commitment to delivering comprehensive analytics solutions in the industrial landscape.

Mareana is an innovative cloud-based Enterprise AI Platform designed to bridge the gaps between isolated data sets in the manufacturing sector, allowing for real-time contextualization, processing, and predictive analytics that facilitate informed business decisions. This platform, known as Mareana Manufacturing Intelligence, serves a diverse range of enterprises—from small businesses to large corporations—by enhancing yield, freeing up capital, and ensuring adherence to regulatory standards. Among its key advantages, Mareana enables users to consolidate various types of data, including traditional paper batch records and unstructured information, into a single accessible location. Furthermore, it allows for the generation of real-time product insights, offering detailed information on product characteristics, identifying process anomalies, and analyzing the effects of new data. Additionally, Mareana helps organizations unlock capital by expediting the release of on-hold batches, improving overall yield, and minimizing non-conformances throughout the production process. Compliance is also streamlined, as the platform ensures accurate reporting by making full use of available data sources and significantly reducing the likelihood of errors. Notably, three of the top ten pharmaceutical companies in the United States have adopted Mareana's platform to enhance their Continuous Process Verification (CPV) and Chemistry, Manufacturing, and Controls (CMC) processes. This widespread adoption underscores the platform's effectiveness and reliability in transforming manufacturing data into actionable insights.