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What is Gritstone?

At the core of our immunotherapy strategy is our deep understanding of antigens and neoantigens, especially when it comes to pinpointing which variations will be transcribed, translated, processed, and ultimately presented on cell surfaces through Human leukocyte antigen (HLA) molecules, making them identifiable to T cells. We utilize Gritstone EDGETM, an innovative platform that leverages machine learning to facilitate this process. The development of cancer immunotherapies that target tumor-specific neoantigens is particularly challenging due to the multitude of mutations present in tumors, where only a select few translate into true tumor-specific neoantigens. To address this intricate issue, we have engineered EDGE's advanced integrated neural network model, which has been trained on millions of data points sourced from a wide array of tumor and normal tissue samples derived from various patient backgrounds. This comprehensive training significantly boosts our ability to accurately identify neoantigens and enhances the overall effectiveness of our immunotherapy approaches, ultimately aiming to provide more targeted and effective treatments for patients. By continually refining our methods and expanding our databases, we strive to stay at the forefront of cancer immunotherapy advancements.

What is Elements Spine SRS?

Brainlab's Elements Spine Stereotactic Radiosurgery (SRS) is an advanced software platform designed to optimize the treatment of spinal metastases. The workflow is characterized by its automation in every stage, which includes detailed anatomical mapping, adjustments for spinal curvature, and precise target identification, ensuring exceptional accuracy and consistency at submillimeter precision. A unique algorithm effectively addresses differences in spinal curvature, enhancing the reliability of image fusion. The system utilizes a patented synthetic tissue model for automatic segmentation, allowing for the accurate identification and labeling of various spinal levels essential for dose calculations. Additionally, tools for defining Gross Tumor Volume (GTV) contours are provided, along with automated recommendations for Clinical Target Volume (CTV) and a cropped spinal canal object that complies with International Spine Consortium Guidelines. The incorporation of AI-driven contouring features facilitates the rapid and accurate delineation of more than 200 anatomical structures, including lymph nodes. This technological development not only simplifies the treatment workflow but also significantly improves patient outcomes in the management of spinal cancer, reflecting a major leap forward in oncological care. As a result, healthcare professionals can deliver more tailored and effective treatment strategies for patients grappling with this challenging condition.

Media

Media

Integrations Supported

Additional information not provided

Integrations Supported

Additional information not provided

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

Gritstone bio

Date Founded

2015

Company Location

United States

Company Website

gritstonebio.com/scientific-platform/

Company Facts

Organization Name

Brainlab

Date Founded

1989

Company Location

Germany

Company Website

www.brainlab.com/radiosurgery-products/elements/spine-stereotactic-radiosurgery/

Categories and Features

Categories and Features

Medical Imaging

Automated Routing
Comparison View
Compliance Management
Data Import / Export
Diagnostic Reporting
Image Analytics
Treatment Planning
Workflow Management

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