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What is LigPlot+?

LigPlot+ is the upgraded version of the original LIGPLOT software, tailored for the automatic generation of 2D illustrations that represent ligand-protein interactions. With its intuitive Java interface, users can easily modify plots by utilizing simple click-and-drag movements, which simplifies the editing process significantly. In addition to the enhanced interface, LigPlot+ boasts numerous important improvements over its earlier version. When examining multiple ligand-protein complexes that exhibit key similarities, the software can automatically generate interaction diagrams that can be displayed either overlapped or side by side, with conserved interactions highlighted for straightforward recognition. Furthermore, the LigPlot+ package includes an improved variant of the original DIMPLOT program, which specializes in visualizing interactions between proteins or domains. Users can select the specific interface of interest, allowing DIMPLOT to create an intricate diagram that maps out the residue-residue interactions within that chosen interface. For added clarity, residues from one interface can also be shown in sequential order, which enhances the usability and overall functionality of the tool. This thorough approach not only aids researchers in comprehending intricate molecular interactions more intuitively but also promotes a deeper understanding of the underlying biological processes at play. Overall, LigPlot+ stands out as an essential resource for scientists delving into the complexities of molecular interactions.

What is BIOVIA Discovery Studio?

The current landscape of the biopharmaceutical industry is marked by its complexity, spurred by rising expectations for greater specificity and safety, the introduction of novel treatment approaches, and an enriched comprehension of intricate disease mechanisms. To effectively navigate this multifaceted environment, it is crucial to have a solid understanding of therapeutic behavior. Advanced modeling and simulation methodologies provide a robust approach to exploring biological and physicochemical phenomena at the atomic level, which can significantly guide experimental research and accelerate both discovery and development phases. BIOVIA Discovery Studio integrates over thirty years of meticulously validated research with state-of-the-art in silico techniques such as molecular mechanics, free energy calculations, and biotherapeutic development, all within a single cohesive platform. This all-encompassing set of tools enables researchers to probe the intricacies of protein chemistry, thereby streamlining the discovery and optimization processes for both small and large molecule therapeutics, from target identification to lead optimization, ultimately improving the drug development workflow. In a time when precision medicine is becoming increasingly crucial, the availability of such advanced tools is essential for fostering therapeutic advancements and ensuring they meet the evolving needs of patients. The ongoing evolution of these technologies promises to further enhance the effectiveness and efficiency of the biopharmaceutical sector.

Media

Media

Integrations Supported

Additional information not provided

Integrations Supported

Additional information not provided

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

EMBL-EBI

Company Location

United Kingdom

Company Website

www.ebi.ac.uk/thornton-srv/software/LigPlus/

Company Facts

Organization Name

Dassault Systèmes

Date Founded

1981

Company Location

France

Company Website

www.3ds.com/products-services/biovia/products/molecular-modeling-simulation/biovia-discovery-studio/

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