List of the Top 25 Advanced Threat Protection (ATP) Software for Small Business in 2026

ThreatLocker® empowers organizations—from businesses and government agencies to academic institutions—with the ability to control exactly which applications are allowed to run in their environments. Built on a Zero Trust foundation, our suite of powerful cybersecurity tools puts control back in your hands. We believe in a future where every organization can operate securely and independently, free from the disruption of cyberattacks. That’s why our team of seasoned cybersecurity experts designed ThreatLocker: to give you the tools to stop threats before they start. With decades of experience developing cutting-edge security solutions, including email and content protection, ThreatLocker is our most advanced and comprehensive platform yet. It’s built to help you reduce risk, simplify your stack, and take control. Learn more at ThreatLocker.com.

ESET Protect Advanced delivers a robust cybersecurity solution tailored for organizations of various sizes. This platform provides cutting-edge endpoint security to combat ransomware and zero-day vulnerabilities effectively. It features full disk encryption to uphold legal standards and safeguard data integrity. The solution employs adaptive scanning, cloud sandboxing, and behavioral analysis to defend against emerging cloud-based threats proactively. Additionally, mobile threat protection encompasses anti-malware and anti-theft measures for both Android and iOS devices. Beyond this, it includes cloud application security, mail server protection, vulnerability assessment, patch management, and comprehensive cloud app safeguards. Enhancements such as multi-factor authentication and extended detection and response (XDR) bolster threat detection and response capabilities. The system offers a unified remote management interface that allows for seamless visibility into threats and user activities. Furthermore, it provides in-depth reporting and tailored notifications to keep users informed of potential risks and system status. This holistic approach ensures that businesses can maintain a strong security posture in an increasingly complex digital landscape.

N-able Mail Assure is a cloud-based solution for email security that delivers sophisticated protection against threats for both incoming and outgoing emails, utilizing collective threat intelligence, a comprehensive email archive, and round-the-clock email continuity services. The platform features multi-tenant web interfaces equipped with preset configurations, detailed reporting, and visual tools that enhance oversight and management of all email transactions. This innovative system employs proprietary technology that analyzes extensive email data to enhance its Intelligent Protection and Filtering engine. By incorporating real-time threat pattern detection and leveraging a diverse array of filtering technologies, N-able Mail Assure effectively safeguards users from spam, viruses, phishing attempts, impersonation, malware, and various other email-related dangers. Additionally, its seamless integration and user-friendly interface ensure that organizations can maintain robust email security with minimal effort.

Trustifi delivers top-tier email security services designed to assist businesses of all sizes in effectively managing threat detection, ensuring compliance with regulations, and implementing data encryption. Its solutions can be easily integrated with popular email platforms such as Outlook and Gmail, as well as any other email server through a relay system. Among the features offered are Advanced Threat Protection, which includes malware and ransomware detection along with Business Email Compromise (BEC) attack prevention alerts, as well as Data Loss Prevention that adheres to strict compliance standards like HIPAA/HITECH, PII, GDPR, FSA, LGPD, and CCPA. Furthermore, Trustifi provides NSA-grade encryption to safeguard sensitive information, and only select Enterprise clients are granted access to customized branding and product white-labeling options. Additionally, personalized training sessions are available for teams to enhance their understanding of the system. Given the diverse encryption needs of organizations, Trustifi recognizes that there is no universal solution for email security, and thus frequently offers tailored solutions upon request, often at no additional cost. This commitment to customization ensures that each client's unique security requirements are effectively addressed.

CrowdStrike Falcon is an advanced cloud-based cybersecurity solution designed to provide strong protection against a wide range of cyber threats, including malware, ransomware, and sophisticated attacks. Leveraging artificial intelligence and machine learning, it allows for immediate detection and reaction to potential security breaches, featuring capabilities such as endpoint protection, threat intelligence, and incident management. The platform uses a lightweight agent that continuously monitors endpoints for signs of malicious activity, ensuring security without significantly impacting system performance. Its cloud infrastructure allows for rapid updates, flexibility, and quick threat mitigation across large and diverse networks. With its comprehensive array of security tools, Falcon equips organizations to proactively thwart, detect, and manage cyber threats, making it a vital asset for modern enterprise cybersecurity. Furthermore, its ability to seamlessly integrate with existing systems not only enhances security measures but also helps to minimize disruptions in operational workflows, reinforcing its value in a rapidly evolving digital landscape. The ongoing commitment to innovation ensures that users remain equipped to face the ever-changing cybersecurity landscape with confidence.

An exceptionally groundbreaking platform. Unrivaled speed. Infinite scalability. Singularity™ delivers unmatched visibility, premium detection features, and autonomous response systems. Discover the power of AI-enhanced cybersecurity that encompasses the whole organization. The leading enterprises globally depend on the Singularity platform to detect, prevent, and manage cyber threats with astonishing rapidity, expansive reach, and improved accuracy across endpoints, cloud infrastructures, and identity oversight. SentinelOne provides cutting-edge security through this innovative platform, effectively protecting against malware, exploits, and scripts. Designed to meet industry security standards, the SentinelOne cloud-based solution offers high performance across diverse operating systems such as Windows, Mac, and Linux. With its ongoing updates, proactive threat hunting, and behavioral AI capabilities, the platform is adept at addressing any new threats, guaranteeing thorough protection. Additionally, its flexible design empowers organizations to remain ahead of cybercriminals in a continuously changing threat environment, making it an essential tool for modern cybersecurity strategies.

Trellix Endpoint Security (HX) facilitates swift and accurate forensic analyses across multiple endpoints. By adopting a holistic security strategy, you can effectively protect and reinforce your workforce across all devices. Trellix's Endpoint Security offerings utilize proactive threat intelligence and strong defense mechanisms at every stage of the attack lifecycle, thereby fortifying your organization's safety and resilience. In an age where threats are continuously evolving, it is vital to ensure the security of your endpoints is never compromised. Explore how our integrated suite of endpoint protection technologies provides you with actionable insights, machine learning features, and additional resources that enable ongoing threat monitoring and attack prevention. The core of endpoint security focuses on safeguarding data and workflows associated with each device connected to your network. Endpoint protection platforms (EPP) work by analyzing files as they enter the network, contributing to a safer digital space for all users. By prioritizing investment in cutting-edge security solutions, organizations can proactively defend against potential cyber threats, thereby significantly enhancing their overall security posture. Additionally, fostering a culture of security awareness among employees can further mitigate risks and ensure a collective commitment to safeguarding digital assets.

To effectively combat adversaries and manage cyber threats, it is essential to start with a cohesive platform. By leveraging a comprehensive suite of prevention, detection, and response tools powered by artificial intelligence, along with top-tier threat intelligence and research, you can establish a robust security framework. Trend Vision One is designed to support a range of hybrid IT environments, facilitating workflow efficiency through automation and orchestration, while also providing tailored cybersecurity services that simplify and unify security operations. The increasing complexity of attack surfaces poses major obstacles, but Trend Vision One offers an all-encompassing security solution that continuously monitors and safeguards your digital landscape. Utilizing fragmented tools may expose you to risks, yet Trend Vision One empowers teams with advanced capabilities for effective prevention, detection, and response. Identifying risk exposure is critical in the current digital climate. By integrating both internal and external data sources within the Trend Vision One ecosystem, you enhance your ability to manage the risks tied to your attack surface. This enriched understanding of key risk elements allows you to minimize the chances of breaches or attacks, thereby enabling your organization to take proactive measures against new threats. Such a thorough approach is vital for successfully navigating the intricate landscape of contemporary cyber risks, ensuring that your security posture is both resilient and adaptive. In the face of evolving threats, a unified strategy becomes not just beneficial, but necessary for maintaining cybersecurity integrity.

Symantec Endpoint Security presents a highly integrated and expansive platform for endpoint protection that is recognized globally. Whether utilized on-site, in a hybrid arrangement, or via the cloud, the cohesive Symantec framework protects a wide range of endpoint devices, from traditional computers to mobile gadgets, by utilizing artificial intelligence (AI) to bolster security decision-making processes. The efficient cloud management system simplifies the processes of protection, detection, and response against intricate threats targeting your endpoints. It is vital to sustain seamless business operations since compromised endpoints have the potential to significantly hinder productivity. By implementing cutting-edge strategies for preventing attacks and minimizing the attack surface, this solution delivers robust security throughout every phase of the attack lifecycle, addressing diverse threats including stealthy malware, credential theft, fileless attacks, and tactics that exploit existing systems. It is crucial to avert dire situations, as large-scale breaches pose a significant threat to Chief Information Security Officers (CISOs). The platform’s advanced attack analytics facilitate the effective identification and remediation of ongoing threats while also safeguarding against the theft of Active Directory credentials, thereby securing your organization’s environment. Furthermore, this all-encompassing strategy empowers organizations to maintain an advantage in an ever-changing threat landscape while continuously adapting to new challenges. In this dynamic environment, staying ahead of potential threats is not just beneficial, but essential for long-term success.

Uncover the hidden dangers that often evade detection by utilizing global intelligence from a vast cyber intelligence network, paired with localized insights tailored for specific clients. By integrating intelligence from multiple control points, organizations can identify and focus on systems that remain compromised and require immediate attention. A single click allows you to contain and resolve all manifestations of a threat effectively. This solution provides a holistic view of threats across IT environments in one unified platform, removing the necessity for manual investigations. You can quickly search for Indicators-of-Compromise and visualize all associated attack events, including involved files, email addresses, and malicious IP addresses. Addressing any remnants of an attack across Symantec-secured endpoints, networks, and emails can be executed with just one click. Moreover, promptly isolating any affected system from the enterprise network significantly boosts overall security and response capabilities. This efficient method not only enhances operational effectiveness but also plays a crucial role in minimizing the likelihood of additional breaches, ultimately fostering a stronger security posture for the organization. Embracing such advanced solutions can lead to a more proactive and resilient cybersecurity strategy.

Protect your organization’s endpoints, confidential information, and users with ESET's extensive multilayered security solutions. The ESET PROTECT platform offers customized security features that are easy to oversee through a cloud-based management console. This approach improves cyber risk management while providing insight into your technological framework. By proactively addressing both established and emerging threats, you can more effectively safeguard your environment. Continuous updates and tailored notifications empower IT teams to promptly respond to any threats that may surface. Furthermore, intelligent predefined policies and automation help IT administrators save time while strengthening defenses against potential cyberattacks. Streamlining compliance with reporting requirements is more straightforward thanks to scheduled reports and a variety of customizable templates. It is vital to remain vigilant, as a user within your network might unwittingly open a malicious email containing a new form of ransomware. In addition, developers on their workstations may accidentally trigger false positives during software compilation, highlighting the necessity for a strong security framework. Therefore, embracing a proactive security approach is crucial for reducing risks related to both user conduct and software development efforts. This comprehensive strategy ensures that your organization remains resilient against ever-evolving cyber threats.

The extensive capabilities of Advanced Threat Protection effectively prevent the execution of complex cyber-attacks. By utilizing features such as freezing, URL scanning, rewriting, the Sandbox Engine, and Malicious Document Encryption, organizations can safeguard their IT systems from various potential dangers. These protective measures are essential in defending against serious threats like Ransomware, Targeted Attacks, and Business Email Compromise. Additionally, the proactive approach ensures that any emerging vulnerabilities are promptly addressed, enhancing overall security resilience.

Secure both on-premises and multi-cloud environments with a comprehensive firewall solution specifically designed for cloud security. The seamless, cloud-based Advanced Threat Protection system efficiently detects and mitigates sophisticated threats, including zero-day exploits and ransomware incidents. With access to an extensive global threat intelligence network, informed by millions of data points, organizations can quickly respond to new and evolving threats. As modern cyber risks, such as ransomware and advanced persistent threats, continue to escalate, the need for sophisticated defensive strategies that ensure accurate threat detection and rapid response becomes paramount. The Barracuda CloudGen Firewall offers a robust array of next-generation firewall technologies, providing immediate defense against a diverse range of network risks, vulnerabilities, and attacks including SQL injections, cross-site scripting, denial of service assaults, and various types of malware. This powerful solution not only bolsters security but also facilitates adherence to industry regulations, thereby becoming an indispensable asset for any organization dedicated to protecting its digital resources. Moreover, with the increasing complexity of cyber threats, the importance of integrating advanced security measures cannot be overstated.

Arista NG Firewall is an enterprise-grade, modular network security solution designed to provide simplified and effective protection for organizations, especially those with limited IT staff and budgets. The platform offers a responsive, browser-based interface that delivers real-time visibility into network traffic, user behavior, and system health through rich, database-driven reports and customizable alerts. It proactively defends against a wide range of threats including malware, phishing attacks, ransomware, drive-by malvertising, and spam, while monitoring encrypted web traffic and rogue applications. NG Firewall includes advanced features such as content filtering, VPN connectivity, application-based bandwidth shaping, and Quality of Service (QoS) to optimize network performance for remote employees, branch offices, and guest Wi-Fi users. Its integration with the Arista Edge Threat Management (ETM) Dashboard allows administrators to centrally orchestrate multiple appliances with zero-touch provisioning, push policy templates, and monitor real-time endpoint security status from a single console. Deployment is flexible, supporting dedicated hardware appliances, virtual machines, and cloud-based environments including AWS and Microsoft Azure. The unique NG Firewall app approach simplifies the user experience and customization for specific deployment needs. Additional tools and expert support help organizations maintain configuration backups and ensure network reliability. The dashboard provides a comprehensive overview of network health, security alerts, and appliance performance at a glance. By combining powerful security with ease of management and scalability, Arista NG Firewall helps organizations reduce complexity, enhance visibility, and maintain secure, high-performing networks.

Our aim is to boost and safeguard productivity in a society that values privacy, permitting both work and leisure to happen anywhere. As the world shifts to cloud solutions, it becomes crucial for cybersecurity to adapt accordingly, protecting your data from the endpoint to the cloud. The significance of mobility and cloud innovation is paramount, considering that many of us now conduct our work and personal activities through digital platforms. Lookout offers a comprehensive solution that integrates endpoint and cloud security technologies, tailored to meet the needs of various sectors, accommodating everyone from individual users to large multinational corporations and governmental bodies. Flexible management of cloud access ensures that security protocols enhance rather than obstruct productivity or user satisfaction. By delivering thorough visibility and insights, we enable you to safeguard your information with accurate access controls while maintaining a fluid and efficient user experience. In essence, our pledge is to guarantee that security measures and productivity can thrive together seamlessly throughout your everyday tasks. This balance not only enhances your operational efficiency but also builds trust in digital interactions.

Check Point Harmony emerges as the pioneering all-encompassing security solution specifically designed for users, devices, and access points within the sector. This groundbreaking solution protects devices and internet connections from sophisticated threats while upholding a Zero-Trust Access model for enterprise applications. In the current landscape of widely dispersed work environments, it's crucial to implement a wide array of security measures across user devices, applications, and networks. Nonetheless, relying on disparate point solutions often creates security gaps and culminates in an intricate infrastructure that can be difficult to manage and scale efficiently. Harmony offers a cohesive alternative that not only minimizes operational expenses but also bolsters overall security. By consolidating six cloud-based security offerings, Harmony guarantees that your protection remains at a flawless 100%. Regardless of where you are, the devices you utilize, or the methods you employ to connect—whether from the comfort of your home or in other locations—your privacy and organizational data are thoroughly safeguarded against potential cyber threats. This comprehensive approach instills a sense of security in an ever-evolving digital landscape, allowing users to focus on their work without the constant fear of cyber vulnerabilities.

Work from anywhere, at any time, and using any device with ease. Experience the freedom of remote work through a cloud-based Windows desktop that guarantees a seamless working experience for your teams, while also providing high levels of security, affordability, and scalability essential for smooth business operations. The Virtual Cloud Desktops come fortified with Advanced Threat Protection in the Windows 2019 Edition, ensuring strong security measures are in place. With a user-friendly WorkDesk management system, maintaining a cohesive remote work environment is as simple as a push of a button. You can take advantage of a Pay-Per-Use model that eliminates upfront expenses, allowing you to pay solely for the hours you utilize. Customize your system configuration effortlessly with a click, enabling swift adjustments to your resources based on your needs. Built-in secure access features come with options that can be tailored to meet specific demands. Storing your data in the cloud guarantees that your information remains secure while also being accessible from any device, at any moment. Designed for user-friendliness, this system requires no manual input, which makes remote work smooth and straightforward for everyone involved. Furthermore, this setup significantly boosts productivity by allowing teams to concentrate on their tasks without the distraction of technical issues, ultimately fostering a more efficient work environment. As a result, remote work becomes not only feasible but also a highly effective way to collaborate and achieve goals.

IRONSCALES provides an innovative, API-integrated email security and training platform powered by AI, designed to assist organizations in combating sophisticated phishing threats. We are convinced that phishing challenges require both human and technological interventions for effective resolution, which is why our combined strategy distinguishes us from others in the market. This dual approach not only enhances security but also empowers users to recognize and respond to threats more effectively.

A centralized management dashboard offers an all-encompassing view of the organization, allowing for enhanced oversight and control. All components within the technology framework are interconnected with a central database, which improves operational efficiency for tasks such as monitoring, investigations, and incident response. This system utilizes both active and passive vulnerability scanners to identify potential issues early on, complemented by pre-configured reports that aid in compliance assessments. Users have the capability to monitor and manage account access and permission changes, reinforcing security protocols. Alerts are triggered for any unusual activities, enabling swift action when necessary. In addition, the dashboard supports remote management capabilities, which allows for quick responses to possible cyber threats. It also features monitoring tools for changes to sensitive data access, ensuring the protection of classified information. To further enhance security, advanced threat protection is implemented to defend endpoints and servers against new and evolving threats, thereby strengthening the overall security framework of the organization. This cohesive strategy not only simplifies operations but also significantly boosts the organization's responsiveness to risks, creating a more resilient infrastructure. Furthermore, the integration of these systems fosters better collaboration among teams, facilitating a proactive approach to cybersecurity challenges.

ESET PROTECT Complete is a comprehensive cybersecurity solution designed to safeguard business endpoints, cloud services, and email systems. It implements advanced techniques to protect against ransomware and zero-day threats, leveraging cloud sandboxing alongside machine learning for enhanced detection capabilities. In addition, it provides full disk encryption to ensure compliance with data protection regulations. The protection extends to mobile devices, file servers, and email servers, incorporating features such as anti-malware, anti-phishing, and anti-spam measures. Organizations can utilize a centralized cloud-based management console for efficient deployment, monitoring, and response to security incidents. Moreover, it comes equipped with vital vulnerability and patch management tools that promptly identify and address software vulnerabilities. This all-encompassing strategy not only strengthens the organization's cybersecurity defenses but also streamlines the management of security measures and responses, making it easier for teams to maintain a proactive security stance. Ultimately, the integration of these diverse features results in a robust platform that not only protects but also enhances operational efficiency.

ESET PROTECT Elite is an advanced cybersecurity solution tailored for enterprises, effectively merging extensive detection and response features with a solid multilayered defense architecture. By employing innovative methods such as adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis, it proficiently tackles zero-day vulnerabilities and ransomware threats. This platform offers contemporary endpoint protection for both desktop and mobile devices, alongside server security that guarantees real-time safety of data and mobile threat defenses. Furthermore, it includes full disk encryption, assisting organizations in achieving compliance with data protection regulations. ESET PROTECT Elite also features robust email security capabilities, which provide protection against phishing, malware, and spam, while safeguarding cloud applications such as Microsoft 365 and Google Workspace. With its automated vulnerability management and patching abilities, the solution streamlines the detection and rectification of security weaknesses across all endpoints, encouraging a proactive stance towards cybersecurity. In conclusion, ESET PROTECT Elite stands out as a holistic solution that effectively meets the complex and ever-changing demands posed by contemporary cybersecurity threats, ensuring that organizations remain secure in a digital landscape fraught with risks.

A budget-friendly collection of network security solutions includes a Managed Network Detection and Response team, the cutting-edge Network Cloaking™ technique, and CINS Active Threat Intelligence. Designed specifically for lean IT teams, this all-encompassing managed security service enables them to concentrate on other critical initiatives. We partner with you to thwart external threats, detect harmful activities, and react promptly to urgent incidents. Our Autonomous Threat Defense and Active Threat Intelligence provide protection that extends beyond the traditional firewall, adding an extra layer of examination for internal network traffic. Sentinel Outpost employs advanced threat defense at the network's edge through Network Cloaking™, effectively blocking malware, exploitation efforts, and various other risks from penetrating the firewall. By utilizing our services, you can significantly boost your overall security posture and guarantee that your network stays robust against the ever-changing landscape of threats. Additionally, our continuous monitoring and proactive measures ensure that you are always one step ahead of potential vulnerabilities.

Reduce the risk of unexpected cyber attacks that could inflict serious damage by implementing Moving Target Defense, a strategy that works effectively across a variety of threats and attack vectors, thereby removing the reliance on indicators or the need to wait for updates and patches. By adopting Morphisec, you significantly lower your risk exposure and drastically reduce technology costs. Integrating Morphisec can revolutionize your security strategy and improve your return on investment. The cutting-edge moving target defense technology created by Morphisec delivers thorough protection against the most significant cyber threats. This solution makes it difficult for attackers to identify the resources needed to circumvent your current defenses due to its ever-changing nature. Additionally, this forward-thinking cybersecurity strategy protects your critical systems with a lightweight agent that is easy to implement and does not require any updates to continuously safeguard your essential infrastructure. Not only does embracing this innovative solution bolster your security framework, but it also enhances overall operational efficiency while providing peace of mind. In an ever-evolving threat landscape, adopting such advanced measures is essential for maintaining robust security.

Stay proactive against sophisticated threats like ransomware and state-sponsored attacks. Equip defenders with the tools necessary to effectively handle risks and refine their security strategies. Transition beyond standalone endpoint solutions to develop a more sophisticated security framework that is based on XDR and Zero Trust principles. Microsoft Defender for Endpoint offers exceptional protection for a wide array of platforms, including Windows, macOS, Linux, Android, iOS, and various network devices, allowing for rapid attack response, resource flexibility, and progressive defense mechanisms. By harnessing the power of cloud scalability and integrated AI, it taps into the most comprehensive threat intelligence available in the market. This all-inclusive solution aids in recognizing every endpoint and network device, such as routers, present in your operational environment. It includes features such as vulnerability management, endpoint protection, endpoint detection and response (EDR), mobile threat defense, and managed hunting, all seamlessly integrated into a single platform, thereby guaranteeing thorough security coverage. With this cohesive strategy, organizations are positioned to fortify their defenses while ensuring they maintain visibility over all their digital assets. Moreover, this integrated approach not only enhances security but also fosters a culture of continuous improvement in cybersecurity practices.

The Sandbox Analyzer proactively detects sophisticated zero-day threats prior to their execution. It automatically directs questionable files to either a secure on-site environment or a Bitdefender-managed cloud sandbox for comprehensive behavioral assessment. Utilizing cutting-edge proprietary machine learning and behavioral heuristic models, the Sandbox Analyzer serves as a critical forensic instrument that enhances the capabilities of Endpoint Detection and Response (EDR) systems, fortifying an organization’s defenses against concealed and intricate threats. This tool validates security findings while improving visibility and facilitating investigations, which results in more effective strategies for threat containment. Files deemed suspicious are subjected to in-depth analysis by activating payloads within Bitdefender's cloud infrastructure or within a secure virtual setup overseen by the client. The sandboxing technology simulates a 'real-world target' environment, prompting the malware to reveal its typical behaviors. After a thorough evaluation, appropriate actions are taken to neutralize any detected threats, thereby ensuring strong cybersecurity measures are in place. Additionally, the ongoing feedback loop created by the Sandbox Analyzer enables organizations to remain proactive in the face of evolving cyber threats, thereby enhancing their overall security posture. This dynamic approach fosters an adaptive defense mechanism that evolves alongside emerging attack vectors.