List of the Top 25 Email Encryption Software for Mid Size Business in 2025

Proton Mail for Business offers a secure and professional email solution trusted by 50,000 organizations. Built with end-to-end encryption and protected by Swiss privacy laws, Proton Mail ensures your sensitive information is safe from unauthorized access and data leaks. Whether you're a small business or a large organization, you can ensure regulatory compliance, reinforce client trust, and keep your communications safe. Easily migrate your team from Google or Microsoft, use your own email domain for your communications, and manage your schedule with Proton Calendar — all in a user-friendly, privacy-focused platform.

PowerDMARC is a powerful email security solution designed to protect your brand's reputation and email communications from various threats such as spoofing, phishing, and ransomware attacks. Utilizing cutting-edge technologies like DMARC, SPF, DKIM, BIMI, MTA-STS, and TLS-RPT, PowerDMARC ensures the safety of your email infrastructure. The platform is designed with user-friendliness in mind, making it easy to manage and monitor your email security measures without dealing with complex configurations. Furthermore, its AI-driven threat intelligence offers critical insights that help in the proactive identification and mitigation of potential threats. With the trust of over 2000 organizations worldwide, including many Fortune 100 companies and government entities, PowerDMARC stands out as a reliable partner in securing your email systems. By choosing PowerDMARC, you invest in a secure future for your email communications and brand integrity.

NeoCertified protects confidential data through our secure email application, which operates seamlessly on our adaptable Cloud-based platform. It is accessible via any web browser and integrates with Microsoft Office 365/Outlook and Gmail, while also offering dedicated mobile applications for both iPhone and Android devices. Since our inception in 2002, we have been delivering secure mail solutions that comply with federal standards, enabling organizations to send and receive secure emails from any web browser or mobile platform. Our service is compatible with all email providers, ensuring that businesses enjoy the flexibility and robust security they require for their communications. Additionally, our commitment to constant innovation guarantees that we meet the evolving needs of our clients in an increasingly digital world.

Encyro provides a suite of secure solutions including encrypted email, electronic signatures, and secure file storage, all designed with an award-winning interface that simplifies the experience for both you and your clients, who won’t need to create portal accounts. With Encyro, you can share files and send encrypted messages directly to any email address, ensuring your data is safeguarded during both transmission and storage, thereby meeting essential compliance requirements like HIPAA, GDPR, FINRA, and SOX. Your clients can securely upload files via a custom-branded upload page without needing to log in or take any extra steps. When it comes to electronic signatures, Encyro provides a seamless experience for remote signing, allowing you to manage login options and signature types to guarantee that the correct individuals are signing documents. Encyro's features include custom branding, automated reminders, reusable e-sign templates, and secure access codes that adhere to NIST-800-63 standards, which can be sent via SMS or text for enhanced security. Furthermore, this platform not only prioritizes user convenience but also fortifies the integrity of your transactions, making it a valuable tool for any business.

Healthcare has developed a user-friendly, scalable method for sending secure, HIPAA-compliant patient information via email. It is crucial for healthcare organizations to prioritize the security and compliance of patient data, particularly in email communication. Paubox Email Suite guarantees encryption, ensuring that your patient information remains safeguarded. Our service eliminates the complexities of portals and passcodes, allowing encrypted emails to be sent directly to recipients' inboxes for easy access. With our innovative tools, encrypting emails in healthcare is made straightforward, and they can seamlessly integrate with your current email systems without necessitating additional training for staff. The design of Paubox’s HIPAA-compliant email service aims to empower IT departments while simplifying the process of emailing protected health information for end-users. Overall, this service enhances both security and usability in healthcare communication.

Mailfence is a provider of encrypted email services that employs OpenPGP-based encryption along with digital signatures for enhanced security. It boasts an array of features that facilitate collaboration while ensuring both security and convenience are maintained. Users can securely store and edit documents through Mailfence Document, and sharing these documents with teammates is as simple as a single button press. Additionally, the Mailfence Calendar helps users manage tasks, meetings, events, and other vital information efficiently. The Contacts feature allows for the storage of contact information and the creation of mailing lists, which enhances overall productivity. Designed with full interoperability in mind, Mailfence can be synced seamlessly with various services. Furthermore, it offers fully customizable whitelabel versions of its interface, catering to diverse branding needs. In a commitment to online privacy, Mailfence contributes 15% of its PRO subscription revenue to organizations like IFF or EDRI. This dedication to supporting privacy advocacy is a testament to Mailfence's values.

EnGuard offers email solutions that comply with HIPAA regulations specifically designed for the healthcare sector, ensuring the protection of sensitive patient information. Their services are tailored to meet the unique communication needs of healthcare professionals.

Spike consolidates your entire workspace into a single Inbox that encompasses email, chat, calendars, calls, team collaboration, and tasks, effectively streamlining your workflow by eliminating the need to toggle between multiple applications. By combining conventional email with instant messaging, Spike's conversational email feature reduces the chaos of lengthy email threads. With real-time communication and live collaboration capabilities, users can enjoy enhanced interactions that foster a more personable communication atmosphere. Available on iOS, Android, Mac, and Windows, Spike ensures that you can stay connected and organized no matter what device you are using. This integration of features is designed to improve productivity and simplify the way you manage your professional communications.

Tuta is an encrypted email platform that prioritizes your privacy, offering secure communication with post-quantum cryptography. The service includes features such as encrypted calendars and contacts, ensuring that all your personal and professional data is protected. Tuta supports mobile apps for iOS and Android, and provides an ad-free, user-friendly experience with customizable options for custom domains. The company focuses on environmental sustainability, using green energy to power all its services while maintaining a zero-knowledge, open-source architecture.

Effortlessly create an endless array of email addresses, each associated with its own list of contacts, all while ensuring the privacy of your actual email account. These addresses can be shared freely, keeping your personal email shielded from telecom companies, governmental agencies, and cybercriminals who might seek to surveil your communications. Each virtual mailbox is equipped with advanced 4096-bit GPG and S/MIME encryption keys and certificates, ensuring that every email stored within MsgSafe-io remains secure and encrypted. You also have the option to tailor the encryption settings for every single contact you engage with. Protect your entire family or organization by managing all identities and email addresses linked to your current domain. If you don't yet own a domain, our domain registration services can help you secure one that integrates effortlessly with MsgSafe-io, complete with essential privacy protections. If you have concerns about the privacy of communication services like FaceTime, Skype, Duo, or Hangouts from major companies like Apple, Microsoft, and Google, consider using our secure and private audio and video communication platforms instead. With these tools, you can invite others to join you through a simple browser link, enhancing both your online security and privacy. This approach not only fortifies your communications but also offers peace of mind in a digital age where privacy is increasingly at risk.

Atomic Mail prioritizes user privacy as an email service provider, offering features such as the ability to create multiple aliases, strong security protocols, and an easy account recovery system. By generating various email aliases, users can better protect their personal information. With zero spam and no advertisements, the service enhances user experience significantly. It also includes email password protection and employs end-to-end encryption, ensuring that only the sender and recipient have access to the content of their messages. Notably, with Zero Access Encryption, Atomic Mail does not have the ability to read your emails. Additionally, users can recover their accounts using a unique seed phrase, allowing them to regain access without sacrificing security measures. This comprehensive approach to privacy and security makes Atomic Mail a reliable choice for individuals who value their online communications.

Introducing Canary, your new AI assistant for email management that not only sends your messages but also identifies important ones, filters out spam, and offers a variety of additional features. With Canary, you can enhance your email experience and keep your inbox organized like never before!

Mimecast Advanced Email Security acts as a robust shield for businesses, safeguarding them against a range of email threats including phishing, malware, impersonation, and spam. Leveraging cutting-edge artificial intelligence and machine learning, Mimecast ensures rapid identification and prevention of threats, thus protecting vital information and ensuring business continuity. The solution features advanced filtering and scanning technologies for both incoming and outgoing messages, dramatically reducing the risk of data breaches while helping organizations meet compliance requirements. Furthermore, Mimecast offers comprehensive reporting and management tools, enabling IT teams to effectively monitor and address potential threats, making it an essential choice for companies seeking top-notch email security. By focusing on both protection and regulatory adherence, Mimecast emerges as an indispensable resource for businesses navigating the complexities of the digital age, ensuring they remain secure and compliant in their operations. This commitment to innovation and excellence is what sets Mimecast apart in the realm of email security solutions.

Proofpoint's Email Protection solutions, offered as both a cloud service and an on-premises option, deliver strong defense mechanisms against a variety of threats, including malware, impersonation emails, and business email compromise (BEC). The system's sophisticated email filtering addresses spam, graymail, and other unwanted communications effectively. Notably, it maintains seamless email functionality even during server disruptions. Esteemed as the leading email gateway in the market, Proofpoint captures a broad spectrum of threats that might slip past other security measures. By leveraging advanced machine learning technology through NexusAI, Email Protection adeptly classifies various email types and detects threats that do not contain harmful payloads, including impostor emails, thanks to its Advanced BEC Defense feature. Furthermore, users can automatically tag potentially dubious emails to raise awareness and recover any email within moments, which ensures a thorough approach to email security. This multi-layered defense strategy not only offers organizations reassurance but also supports them in navigating the intricate landscape of email communications while minimizing risks. The comprehensive features work together to create a secure environment where email interactions can thrive without constant worry.

Senders maintain complete control by restricting what recipients can do with content, including the ability to print, share, or download, and they can revoke access whenever needed. Identillect remains responsive to regulatory changes through continuous research, allowing you to concentrate on your primary responsibilities. The platform is designed to be easily navigable for both senders and recipients, who do not need to register or subscribe to receive messages. Enhance your secure communications effortlessly through Outlook by utilizing Identillect’s advanced vCard technology. You have the flexibility to set your desired security level and implement company-wide policies that limit recipient permissions across your network, ensuring consistent protection. This add-in simplifies message security and responses while you're on the go, offering all the functionalities of Delivery Trust® – Web Only. Its user-friendly interface guarantees a smooth implementation process across your organization without the burden of a steep learning curve. Additionally, the add-in provides full access to all features of DELIVERY TRUST® – Web Only, thereby guaranteeing extensive security for every communication you send. By leveraging these capabilities, you can confidently safeguard sensitive information and maintain control over your communications at all times.

Skiff offers a fully private encrypted workspace that seamlessly integrates with Mail, Calendar, and Pages, ensuring a secure platform for communication and teamwork. The products are meticulously crafted with a strong emphasis on user privacy and security, employing end-to-end encryption (E2EE) so that sensitive data and private keys remain exclusively under your control, granting you uninterrupted access to your email content. Users can benefit from generous free tiers that provide 10 GB of complimentary storage for emails, documents, attachments, and notes, along with the option to create up to four free email aliases to safeguard your identity. Moreover, Skiff Mail stands out as an open-source initiative that utilizes transparent cryptographic techniques and is subject to frequent external security assessments, with its whitepaper and source code available on skiff.com for public review. The platform is free from trackers and advertisements, allowing users to upgrade their services using cryptocurrency payments across various currencies, while ensuring that your personal information is never sold, shared, or collected. In this way, Skiff not only prioritizes security and privacy but also fosters a community-driven approach to its development and user experience.

ChatOdyssey is a privacy-focused platform offering a comprehensive range of tools designed to protect your personal data and communications. From encrypted instant messaging to anonymous file sharing, email masking, and phone number relay, the platform ensures that your identity remains protected while you interact online. In addition to these core services, ChatOdyssey provides advanced security features such as metadata cleaning, malware scanning, and secure document viewing, all aimed at giving users complete control over their privacy. The platform’s password strength checker, passphrase generator, and encryption tools further support individuals looking to safeguard their digital presence. Users can also check for compromised accounts with the Data Breach Checker, ensuring they stay one step ahead of potential threats. Whether you’re concerned about online trackers or simply want to protect your communications from prying eyes, ChatOdyssey offers the tools needed to maintain your privacy with ease. The platform’s no-hassle design and comprehensive security features make it an essential tool for anyone seeking enhanced digital privacy and protection from the dangers of the online world.

StartMail provides email services that ensure your privacy and security are at the forefront of its offerings. You have the ability to create temporary email addresses whenever necessary to shield your personal inbox from unwanted junk mail. Upholding privacy as a fundamental human right, StartMail simplifies the process of protecting your information. With a single click, you can send messages that are encrypted with a password, even to those who do not use encryption themselves. Our service adheres to strict Dutch privacy laws, recognized as some of the strongest in the world, while also conforming to European privacy regulations. For businesses, we provide the option of custom email addresses linked to your own domains. Moreover, there's no need for software installation—setting up your account is quick and effortless, taking only a few minutes. By choosing StartMail, you can enjoy peace of mind knowing that your communication is secure and your privacy is respected.

MDaemon Technologies has created the email threat detection technology utilized by Security Gateway. For over two decades, this trailblazer in the email industry has been safeguarding email servers from various dangers like viruses, spam, and phishing. Organizations rely on their expertise to maintain the security of their email exchanges. Their protection extends to all email platforms, such as Microsoft Exchange and Office 365, among others. With a dedicated team of email security experts, Security Gateway simplifies the management of your organization’s email security needs. Utilizing the latest advancements in email threat detection technology and policy enforcement tools, Security Gateway ensures that legitimate emails are efficiently delivered to and from your users. Additionally, the cloud service offered by Security Gateway is straightforward to implement, allowing you to concentrate on other vital responsibilities. To learn more about the functionalities of Security Gateway, be sure to check out this informative video.

SenditCertified provides a distinctive range of patented cloud services designed for secure email exchanges, file storage, and signature-required transactions, all backed by robust security measures. With this platform, users can effortlessly manage their secure communications while being safeguarded against various threats. A notable feature is the opportunity to try their secure, biometric-enabled email solutions free for 14 days, with no credit card required. Their cutting-edge technology ensures the secure handling of sensitive medical data, such as patient identification, diagnoses, referrals, test results, and medication details, while fully adhering to HIPAA regulations. Moreover, SenditCertified supports private conversations that respect attorney-client privilege, enabling the safe transfer of emails, documents, and multimedia. Users enjoy the ability to control access to their communications by determining who can view, print, save, or download files, significantly boosting privacy and security. Choosing SenditCertified means investing in reliable and secure communication solutions that provide users with confidence and peace of mind, making it an ideal choice for personal and professional use.

Posteo is a Berlin-based email service provider that emphasizes sustainability and privacy, providing users with an ad-free, encrypted email experience. Powered entirely by green energy, Posteo costs just €1 per month, offering a full suite of features, including email, calendar synchronization, and address book management, all accessible from various devices. The platform is designed for users who value privacy, as Posteo does not collect personal data or engage in user profiling, and it provides easy-to-use encryption options for all its services. Furthermore, Posteo offers additional privacy features such as encrypted calendars, two-factor authentication, and the ability to encrypt the entire mailbox. Posteo’s commitment to privacy extends beyond email services; they also focus on reducing their environmental footprint by using sustainable resources like Green Planet Energy and operating an environmentally responsible workplace. By rejecting advertisements, user tracking, and the collection of IP addresses, Posteo ensures that customers' information stays private and secure. The company’s business model focuses solely on serving its users without relying on advertisers or investors, making it a trusted provider for those seeking uncompromised privacy. Through a seamless migration process, users can easily move from other email providers while ensuring data stays secure and encrypted during the transfer. Posteo is an ideal solution for privacy-conscious individuals who want an efficient and secure communication platform with a strong commitment to both user privacy and environmental sustainability.

Efficiently categorize deceptive emails while proactively detecting and isolating questionable URLs. Utilizing big data analytics enables precise classification of mass email communications. This comprehensive solution integrates seamlessly with both Google Workspace and Microsoft 365. Spambrella's Email Security and User Awareness Training technology is trusted by numerous leading security-focused organizations worldwide, spanning various industries and regions. By partnering with Spambrella, you can consolidate your email security strategies and user training initiatives on an international scale. Acting as your dedicated email security team, Spambrella ensures a smooth transition while possessing the technical know-how of other major providers like Symantec.cloud, Mimecast, and MxLogic. To safeguard your email users from potential threats, reach out today to arrange a demonstration with our cybersecurity specialists and enhance your email protection strategy.

You can send and receive encrypted emails that adhere to HIPAA and GLBA regulations, ensuring your communications remain secure. Known previously as Protected Trust Email Encryption, our service has now been rebranded to Send It Secure by Protected Trust. This change reflects our evolution and the expansion of our email encryption capabilities, as well as our broadening range of services. We decided it was the right time for a new identity to represent our commitment to delivering a reliable solution in the marketplace. This rebranding emphasizes our dedication to enhancing user experience through tailored improvements. As a recognized leader in securely transmitting sensitive information, we prioritize maintaining your trust and protecting your data at all costs. We are excited to introduce you to our upgraded email encryption solution, Send It Secure by Protected Trust, and are committed to effectively meeting your secure communication requirements with greater efficiency. Our goal is to ensure that your experience with our services is both seamless and secure.

Who can access your emails? With traditional emails, you, the recipient, and all email service providers may have visibility into the contents, along with potential others. In contrast, end-to-end encryption restricts access solely to the sender and the intended recipients, ensuring greater privacy. The iOS app known as Letterbox enhances the end-to-end encryption experience, supporting a wide range of email services and employing the widely recognized OpenPGP encryption protocol. Although Letterbox operates like many other email applications, it specifically emphasizes the security status of both incoming and outgoing communications, empowering users to identify which emails are secure and which are not. Being a free and open-source email client for iOS, Letterbox aligns with an ongoing research project at Freie Universität Berlin. While it is still in development, users will soon have the chance to try the app on their devices via Apple's TestFlight platform, making secure communication increasingly available to the public. This development not only aims to improve user understanding of email security but also strives to maintain a seamless and intuitive user interface. As technology evolves, the importance of secure communication will only continue to grow.

Achieve effortless data privacy compliance with PBHS Secure Mail, a comprehensive encrypted messaging platform that meets HIPAA standards, tailored for healthcare providers including physicians, dentists, and medical facilities. The platform's user-friendly design eliminates the need for installation, configuration, or ongoing maintenance, enabling access from any device and location. Sharing essential documents, such as radiographs, CT scans, and messages is simplified, with all information well-organized for easy retrieval by your entire team. Initiating use is straightforward; just log in with your ADA Membership ID. Furthermore, the optional Outlook Plug-in enables the convenient sending and receiving of messages directly within Microsoft Outlook on your computer, ensuring that treatment letters and private communications from your management software remain encrypted. Radiographs dispatched from your digital x-ray systems to Outlook are also safeguarded. You can maintain your regular email interactions with colleagues and patients while upholding HIPAA compliance, which facilitates an effortless transition to secure communications. This innovative solution allows you to prioritize delivering exceptional care and ensures the highest levels of data security are upheld throughout your practice. By utilizing PBHS Secure Mail, healthcare professionals can enhance their communication efficiency while protecting sensitive information.