List of the Top 19 On-Prem Endpoint Detection and Response (EDR) Software in 2025

Safetica Intelligent Data Security ensures the protection of sensitive enterprise information no matter where your team operates. This international software organization specializes in providing solutions for Data Loss Prevention and Insider Risk Management to various businesses. ✔️ Identify what needs safeguarding: Effectively detect personally identifiable information, intellectual property, financial details, and more, no matter where they are accessed within the organization, cloud, or on endpoint devices. ✔️ Mitigate risks: Recognize and respond to dangerous behaviors by automatically detecting unusual file access, email interactions, and online activities, receiving alerts that help in proactively managing threats and avoiding data breaches. ✔️ Protect your information: Prevent unauthorized access to sensitive personal data, proprietary information, and intellectual assets. ✔️ Enhance productivity: Support teams with live data management hints that assist them while accessing and sharing confidential information. Additionally, implementing such robust security measures can foster a culture of accountability and awareness among employees regarding data protection.

SecPod SanerNow stands out as a premier unified platform for endpoint security and management, empowering IT and security teams to streamline and automate essential cyber hygiene processes. Utilizing a sophisticated agent-server framework, it guarantees robust endpoint security alongside efficient management capabilities. The platform excels in vulnerability management by providing comprehensive scanning, detection, assessment, and prioritization features. Available for both on-premise and cloud deployment, SanerNow seamlessly integrates with patch management systems to facilitate automatic updates across major operating systems like Windows, macOS, and Linux, as well as numerous third-party software applications. What truly sets it apart is its expansion into additional critical functionalities, which include security compliance management and IT asset tracking. Moreover, users can leverage capabilities for software deployment, device control, and endpoint threat detection and response. All of these operations can be conducted remotely and automated, reinforcing defenses against the evolving threats posed by modern cyberattacks. This versatile platform not only enhances security but also simplifies the management of IT assets, making it an invaluable tool for organizations of all sizes.

Fortinet emerges as a key global player in the cybersecurity sector, notable for its comprehensive and integrated approach to safeguarding digital infrastructures, devices, and applications. Founded in 2000, the organization provides a wide range of products and services, including firewalls, endpoint protection, intrusion prevention systems, and secure access solutions. A cornerstone of its offerings is the Fortinet Security Fabric, a unified platform that seamlessly combines various security tools to enhance visibility, automation, and provide real-time threat intelligence across the entire network. Renowned for its dependability among businesses, government agencies, and service providers worldwide, Fortinet prioritizes innovation, scalability, and performance, thereby reinforcing its defenses against the constantly shifting landscape of cyber threats. In addition to its protective capabilities, Fortinet’s dedication to enabling digital transformation and ensuring business continuity highlights its essential role within the cybersecurity landscape, positioning itself as a trusted partner for organizations striving to navigate modern security challenges effectively. With a focus on proactive measures and cutting-edge solutions, Fortinet continues to adapt and evolve to meet the demands of an increasingly complex digital world.

VIPRE Endpoint Protection delivers a strong defense against the increasingly advanced malware threats of today, ensuring top-tier security without the added complications often associated with other endpoint solutions. It is engineered to maintain a low total cost of ownership while integrating cutting-edge machine learning, real-time behavioral analysis, and a worldwide threat intelligence network for proactive security measures. This cloud-based solution harmonizes a contemporary, efficient endpoint defense with time-saving features, allowing your organization to operate seamlessly. VIPRE's protection spans file, application, and network levels, ensuring thorough malware defense across all potential attack vectors. Additionally, it empowers organizations to implement detailed internet usage policies with specific safeguards that fulfill employers' responsibilities for duty of care. With dynamic, real-time dashboards, users gain an intuitive and comprehensive overview of their endpoint environment, simplifying the process of monitoring security status and responding as necessary. By choosing VIPRE Endpoint Protection, organizations can achieve enhanced security with reduced complexity and increased efficiency. Whether you need a core next-generation antivirus solution, a full endpoint detection and response (EDR) option, or a combined EDR and managed detection and response (MDR) package, VIPRE offers tailored solutions to meet your needs. Each option is designed to ensure your organization's security while minimizing disruption to your daily operations.

Automox operates in the cloud and is accessible worldwide. It streamlines the management of operating system and third-party patches, security settings, and custom scripts for both Windows and Mac systems through a unified interface. This enables IT and security operations teams to swiftly establish control and enhance visibility across virtual, on-premises, and remote endpoints, all while avoiding the need for costly infrastructure deployments. By simplifying these processes, Automox ensures that organizations can maintain robust security and compliance efficiently.

Enginsight is a robust cybersecurity platform developed in Germany, designed to integrate threat detection with protective strategies effectively. Featuring automated security audits, penetration testing, IDS/IPS, micro-segmentation, vulnerability assessments, and risk analysis, this solution empowers businesses of all sizes to implement and oversee effective security measures through an intuitive dashboard. It enables the automatic assessment of your systems, allowing you to quickly evaluate the security status of your IT assets. Completely built with a security-first approach, Enginsight functions without reliance on external tools. It continuously scans your IT environment to identify devices, creating a real-time overview of your IT infrastructure. With its automatic detection capabilities and an exhaustive inventory of IP network devices, which includes detailed categorization, Enginsight acts as a comprehensive surveillance and security barrier for your Windows and Linux servers, as well as endpoint devices like PCs. Embark on your 15-day free trial today and take a step towards enhancing your organization's cybersecurity.

Plurilock DEFEND offers continuous authentication during active computing sessions by utilizing behavioral biometrics in conjunction with the keyboard and mouse devices already employed by employees. The system operates through an invisible endpoint agent and applies machine learning algorithms to assess and verify a user's identity based on their console interactions, eliminating the need for visible authentication processes. When integrated with SIEM/SOAR systems, DEFEND enhances the ability to triage and respond to security operations center alerts by providing high-confidence identity threat intelligence. Furthermore, by seamlessly integrating into login and application workflows, DEFEND delivers immediate identity verification signals in the background, enabling a truly seamless login experience once identity has been established. The DEFEND solution is compatible with various platforms, including Windows, Mac OS, IGEL, and Amazon Workspaces VDI clients, ensuring broad applicability across different environments. This flexibility makes DEFEND a versatile choice for organizations looking to enhance their security posture without disrupting user experience.

Alert Logic stands out as the sole managed detection and response (MDR) service that offers extensive protection across public clouds, SaaS, on-premises, and hybrid settings. With our advanced cloud-native technology and dedicated team of security professionals, we safeguard your organization around the clock, ensuring a prompt and effective response to any potential threats that may arise. Our commitment to comprehensive security enables businesses to focus on their core operations with peace of mind.

HCL BigFix serves as a cutting-edge AI Digital+ endpoint management platform that enhances employee experiences while automating infrastructure management with intelligence. This platform provides comprehensive solutions for securing and managing endpoints across nearly 100 operating systems, ensuring ongoing compliance with industry standards, and transforming vulnerability management through exceptional cybersecurity analytics. It stands as the singular solution capable of securing any endpoint across all clouds and industries. Additionally, HCL BigFix is unique in its ability to empower IT Operations and Security teams to fully automate the discovery, management, and remediation processes, whether in on-premise, virtual, or cloud environments, without being hindered by operating systems, location, or connectivity issues. Unlike traditional, complex tools that only cover a fraction of your endpoints and require extended periods for remediation, BigFix swiftly identifies and resolves endpoint issues, achieving over 98% success rates on initial patch attempts, thus setting a new standard in endpoint management efficiency.

CybrHawk stands out as a leading provider of risk intelligence solutions focused on information security, dedicated to delivering enhanced visibility for clients to reduce the likelihood of cyber-attacks. Our offerings empower organizations to establish robust cyber defenses, effectively prevent security breaches, detect malicious activities in real time, prioritize response efforts, and proactively prepare for emerging threats. Moreover, we have developed a comprehensive approach that encompasses a wide array of cybersecurity solutions tailored for businesses of different scales and complexities, ensuring that every organization can bolster its defenses against cyber risks. In a rapidly evolving digital landscape, our commitment to innovation and excellence distinguishes us as a trusted partner in the fight against cybercrime.

Businesses aiming to stand out must transition from a reactive stance to one of proactive control. Firms interested in enhancing their ongoing improvement efforts and maximizing their investments can benefit greatly. With GoSecure Titan®'s Managed Security Services, which encompass our Managed Extended Detection & Response (MXDR) Service, alongside our Professional Security Services, we position ourselves as your trusted partner in safeguarding against breaches and ensuring a secure environment for your operations. By choosing us, you can focus on growth while we handle your security needs.

ITsMine Beyond DLP™ redefines the approach to Data Loss Prevention (DLP) by offering comprehensive protection against various data threats for organizations. It does away with the necessity of policies or endpoint agents, which allows employees to work without disruption while still safeguarding data even after it has been compromised. As data loss incidents grow more frequent and severe, caused by both deliberate actions and accidental leaks, adopting a new security framework is crucial. Beyond DLP™ presents an innovative methodology for organizations to oversee and protect their data, irrespective of where it is stored—be it on internal networks or external cloud services. This solution enables organizations to uphold rigorous security protocols for data housed in both on-premises systems and cloud infrastructures. Moreover, it enhances employee productivity while ensuring that sensitive data is effectively monitored and controlled. In addition, it streamlines adherence to a range of data protection laws, such as GDPR, CCPA, PCI, and HIPAA, offering powerful access control, identifying potential data breaches, and providing detailed reporting features. Consequently, organizations can enhance their data security management while preserving operational efficiency, making it an essential tool in the modern digital landscape.

Achieve robust protection for your IT infrastructure through comprehensive cyber risk management, backed by the expertise of ESET professionals who are always on hand. ESET MDR offers industry-leading multilayered capabilities for prevention, detection, and response, combined with exceptional support to help you make the most of these solutions. Enjoy a holistic strategy aimed at prevention, detection, and remediation, applicable to computers, smartphones, and virtual machines. This proactive cloud-based defense system is specifically designed to tackle zero-day vulnerabilities and emerging threats that have never been encountered before. Integrated into the ESET PROTECT platform, the XDR-enabling feature significantly enhances your visibility and strengthens breach prevention efforts. Furthermore, a robust encryption solution protects system disks, partitions, and entire devices, ensuring compliance with legal requirements. With ESET's expert guidance readily available, you can optimize the return on investment from your ESET products while effectively securing your digital environment. Not only does ESET safeguard your assets, but it also empowers your organization to flourish amidst the growing complexities of the cyber landscape. In today's fast-evolving digital world, ESET stands as a partner in your success by providing innovative solutions that adapt to the ever-changing threats you face.

Identifying the nature of a threat and responding promptly and adaptively is essential for effective cybersecurity. Sangfor Endpoint Secure offers a unique approach to defending against malware and advanced persistent threats (APTs), setting itself apart from conventional next-generation antivirus (NGAV) and endpoint detection and response (EDR) solutions. This system operates within a holistic cooperative security framework that includes Sangfor's NGAF, IAM, and Cyber Command, facilitating a coordinated reaction to malware attacks and APT incidents across the entire organizational network while streamlining management and operational tasks. Its adaptable design accommodates the diverse needs of organizations, whether they favor on-premise, cloud, or hybrid management options. Additionally, Endpoint Secure integrates smoothly with Sangfor NGAF, enhancing the capability for swift responses to malware threats. This solution not only allows for the quick detection and neutralization of harmful lateral (east-west) and command-and-control (north-south) communications but also ensures comprehensive asset identification throughout the network. In light of the increasing complexity of modern cyber threats, such an integrated system is vital for sustaining strong cybersecurity measures, ultimately fostering a more resilient organizational infrastructure. By employing this approach, companies can better prepare for and mitigate the risks posed by evolving cyber threats.

Transforming the landscape of endpoint threat detection, investigation, and response is vital for contemporary cybersecurity approaches. By significantly reducing the time it takes to detect and respond to threats, Trellix EDR enables security analysts to prioritize risks more effectively, thereby mitigating potential damages. The guided investigation capability simplifies the analysis process by independently generating and answering crucial inquiries while gathering, summarizing, and visualizing data from multiple sources, which lessens the need for extra SOC resources. With the advantages of cloud deployment and advanced analytics, proficient security analysts can shift their focus from tool maintenance to strategic defense measures. Choosing the right solution that fits your organization is essential; this may involve leveraging a current Trellix ePolicy Orchestrator (Trellix ePO) on-site management system or selecting a SaaS-based Trellix ePO to ease infrastructure demands. By alleviating administrative tasks, senior analysts gain the ability to dedicate their skills to proactive threat hunting, which not only speeds up response times but also strengthens the overall security framework. This innovative method of safeguarding endpoints ultimately fosters a more agile and robust security environment, ensuring organizations are better equipped to handle emerging threats.

Recognize files classified as harmful through specific signatures identified by researchers, publishers, and our Cyber Threat Intelligence (CTI) team. Establish detection alerts for Indicators of Compromise (IOCs) associated with recognized threats while enhancing them with custom IOCs to tailor the Endpoint Detection and Response (EDR) system to your unique environment. Our research and development team continuously improves its algorithms, enabling you to detect binaries that are typically regarded as undetectable. Leverage over 1,200 detection rules to identify potential new threats that may not be captured in current IOCs or signature databases. A dedicated engine has been developed to efficiently combat ransomware, while also safeguarding your EDR system from unauthorized changes, thereby ensuring its proper functionality. In addition, it blocks the download and installation of harmful or outdated drivers using our frequently updated list. If any malicious driver attempts to compromise your EDR's monitoring and protective features, you will be promptly notified to take necessary actions. This proactive strategy not only fortifies defense mechanisms but also adapts to the continuously changing landscape of cyber threats, ensuring your security remains resilient and effective. Furthermore, maintaining vigilance and employing these advanced tools will significantly strengthen your overall cybersecurity posture.

For those seeking comprehensive endpoint protection, an observability framework, effective detection and response strategies, or crucial security functionalities, LimaCharlie’s SecOps Cloud Platform offers the means to establish a security program that is both flexible and scalable, adapting swiftly to the evolving tactics employed by adversaries. This platform ensures robust enterprise defense by merging essential cybersecurity functions while effectively tackling integration challenges and eliminating security gaps, thus improving defenses against modern threats. Moreover, the SecOps Cloud Platform fosters a unified environment that facilitates the seamless creation of customized solutions. With features such as open APIs, centralized monitoring of data, and automated detection and response mechanisms, this platform represents a significant advancement in contemporary cybersecurity methodologies. By harnessing these sophisticated tools, organizations can markedly strengthen their security measures, ensuring that their assets are more effectively protected. Ultimately, the integration of such innovative technologies can lead to a more resilient approach to cybersecurity in an increasingly perilous landscape.

ESET Inspect is an advanced endpoint detection and response (EDR) tool created by ESET, designed to provide thorough visibility, threat detection, and incident management capabilities for businesses. This solution plays a critical role in helping organizations identify, analyze, and mitigate sophisticated cyber threats that could bypass traditional security measures. By continuously observing endpoint activities in real time, ESET Inspect utilizes behavioral analytics, machine learning, and threat intelligence to reveal suspicious behavior, anomalies, and potential security breaches. It integrates seamlessly with ESET’s endpoint protection suite, offering a unified view of network security and allowing security teams to respond promptly to threats through automated actions or manual approaches. Essential features like threat hunting, detailed reporting, and customizable alerts empower businesses to strengthen their cybersecurity strategies while proactively addressing potential weaknesses. Additionally, ESET Inspect's flexibility enables it to adapt to the specific security requirements of various organizations, ensuring they can effectively combat the ever-evolving landscape of cyber threats. Thus, organizations can maintain a proactive stance in safeguarding their digital environments against emerging risks.

EDR operates continuously around the clock, but it doesn't have to be your sole responsibility. Implementing EDR is an effective strategy for enhancing your security posture, although transforming a tool into a full-scale enterprise solution can be a daunting and time-intensive task. Red Canary stands out with its top-of-the-line technology, supported by a skilled team that has overseen numerous EDR deployments over time. We collaborate closely with your team to deliver immediate benefits. While various EDR vendors offer Software as a Service (SaaS) solutions, many come with limitations on data collection to safeguard their resources. In contrast, Red Canary provides comprehensive visibility EDR without the need for on-premises installation or extensive data retention requirements. Since endpoints are critical points of activity, capturing, indexing, and storing high-volume telemetry necessitates considerable hardware and software investments. With Red Canary, you gain the ability to store limitless telemetry data either locally or in the cloud, and accessing this information is made straightforward whenever required. This seamless approach not only enhances your operational efficiency but also strengthens your overall security framework.