List of the Top 14 HIPAA Compliance Software for Microsoft 365 in 2026

Safetica Intelligent Data Security ensures the protection of sensitive enterprise information no matter where your team operates. This international software organization specializes in providing solutions for Data Loss Prevention and Insider Risk Management to various businesses. ✔️ Identify what needs safeguarding: Effectively detect personally identifiable information, intellectual property, financial details, and more, no matter where they are accessed within the organization, cloud, or on endpoint devices. ✔️ Mitigate risks: Recognize and respond to dangerous behaviors by automatically detecting unusual file access, email interactions, and online activities, receiving alerts that help in proactively managing threats and avoiding data breaches. ✔️ Protect your information: Prevent unauthorized access to sensitive personal data, proprietary information, and intellectual assets. ✔️ Enhance productivity: Support teams with live data management hints that assist them while accessing and sharing confidential information. Additionally, implementing such robust security measures can foster a culture of accountability and awareness among employees regarding data protection.

Atlantic.Net provides Cloud, GPU Cloud, Dedicated, Bare Metal Hosting, and Managed Services. Our hosting options are crafted to enable you to concentrate on your primary business activities and applications, all while adhering to necessary security, privacy, and compliance standards. Specifically, our Compliance Hosting services cater to the healthcare and financial services sectors, which demand stringent data security measures. Atlantic.Net's compliance hosting offerings undergo independent certification and auditing by third-party evaluators, ensuring they fulfill HIPAA, HITECH, PCI, and SOC criteria. With a focus on proactive, results-driven digital transformation, we strive to support you from the initial consultation right through to your ongoing operational needs. Our managed services provide a significant competitive edge, enhancing your organization's productivity and efficiency. Additionally, you can effectively navigate your industry's regulatory landscape by establishing an environment that is compliant with HIPAA, HITECH, PCI DSS, and GDPR standards, while enjoying peace of mind regarding data protection. This comprehensive approach not only safeguards your data but also fosters trust with your clients and stakeholders.

Whether you're utilizing a desktop setup, a multifunction printer (MFP), or managing tasks on a mobile device, eGoldFax offers seamless fax communication that redefines convenience. Experience the endless possibilities that eGoldFax brings, allowing you to effortlessly reroute incoming faxes to your chosen destination—be it an email, a network folder, or a specific printer—granting you unparalleled flexibility to manage your faxes according to your individual workflow preferences. eGoldFax is compatible with leading Multi-Function Product manufacturers such as Sharp, Kyocera, Xerox, Konica Minolta, Canon, HP, Ricoh, Lexmark, and others, with an API available for those needing advanced workflow solutions. Beyond transforming the faxing process, eGoldFax also supports organizations in meeting compliance requirements for various regulatory standards, including HIPAA, GDPR, PCI, and FERPA. Join a multitude of satisfied clients who rely on eGoldFax to protect their confidential data while ensuring compliance with essential industry regulations, thus enhancing the overall integrity of their operations.

Ostendio stands out as the sole integrated platform for security and risk management that harnesses the potential of your most valuable asset: your workforce. For over ten years, this security platform has been refined by industry experts and innovators, addressing the everyday obstacles that businesses encounter, such as escalating external threats and intricate internal challenges. With Ostendio, you gain access to intelligent security and compliance solutions that evolve alongside your organization, empowering you to build trust with customers and achieve excellence in audits. Furthermore, Ostendio proudly holds the status of a HITRUST Readiness Licensee, underscoring its commitment to security standards. This unique combination of features makes Ostendio an essential partner in navigating the complexities of modern business security.

Meet Upvio, an innovative practice experience platform crafted to enhance workflows, reduce repetitive administrative duties, and excel in the modern, digital-driven healthcare environment. Designed specifically for healthcare providers across a multitude of specialties and organizations, Upvio presents a robust suite of tools that streamline and automate essential operations such as appointment scheduling, telehealth services, messaging, patient monitoring, and payment processing. With a strong commitment to adhering to industry regulations like HIPAA and GDPR, Upvio addresses prevalent issues in the healthcare sector, including complicated user interfaces, technical difficulties, communication barriers, patient engagement hurdles, data management challenges, revenue generation, scalability concerns, customization options, and reporting needs. What sets Upvio apart is its unique array of features tailored for the healthcare industry, which includes automated reminders, customizable forms, extensive telehealth functionalities, a virtual waiting room, and the ability to assess remote vital signs. This budget-friendly solution not only provides seamless integration but also accommodates users with varying degrees of technical skill, ensuring that dedicated account managers are available for efficient setup and ongoing assistance. By choosing Upvio, healthcare providers can significantly enhance their operational efficiency and improve patient experiences.

Fax.Plus is a trustworthy and secure online fax solution designed for individuals, small to medium enterprises, healthcare professionals, and various organizations, enabling them to effortlessly send and receive faxes via their computers or mobile devices. Key features of Fax.Plus include: * Compliance with HIPAA regulations for secure faxing * Absence of certain integration options * Seamless integration with G Suite * An encrypted archive that stores all sent and received faxes for later access * Availability across multiple platforms, including web, Android, and iOS * The option to obtain toll-free fax numbers * Global coverage for users around the world. With its variety of features, Fax.Plus caters to diverse faxing needs while ensuring security and accessibility.

Caspio stands out as the premier no-code solution for building online database applications without the need for programming skills. The platform offers a comprehensive suite of tools necessary for the digital transformation of business processes and workflows, including a cloud-based database, a user-friendly app builder, robust security measures, adherence to regulatory standards, and a scalable infrastructure that serves a global clientele. Over 15,000 organizations around the world rely on Caspio, which is available for free to new users. Since its inception in 2000, Caspio has been at the forefront of cloud technology, continuously enhancing its database platform. It is designed to accommodate HIPAA compliance, and all subscription plans come with the advantage of unlimited users at competitive pricing, making it an attractive option for businesses of all sizes.

OpenText CloudAlly Backup offers a unified, cloud-native platform designed to protect SaaS environments from data loss due to user error, ransomware, sync corruption, malicious intent, and service outages. It provides automated or on-demand immutable backups for Microsoft 365, Google Workspace, Salesforce, Box, Dropbox, and other major cloud services, ensuring full recovery across emails, files, metadata, calendars, drives, and collaboration tools. Organizations can store data in CloudAlly’s secure AWS S3 infrastructure across nine global data centers or use their own cloud accounts for maximum control. Unlimited retention, granular recovery tools, and 1-click restore capabilities simplify retrieval of individual items, entire accounts, or full system snapshots. Powerful features such as anomaly detection, keyword search, sandbox seeding, and data comparison strengthen security and productivity for large or distributed teams. CloudAlly’s security architecture includes AES-256 encryption, strict access controls, MFA, HIPAA and GDPR compliance, and ISO certifications, making it one of the most trusted SaaS backup solutions on the market. The MSP-friendly Partner Portal offers centralized oversight, subscription management, reporting, and white-label branding to support scalable service delivery. For SMBs and enterprises alike, CloudAlly delivers cost-effective protection with pay-as-you-go pricing and a zero-tier licensing model. Customers benefit from a proven track record, protecting billions of files monthly and completing thousands of backups per day. Ultimately, CloudAlly ensures that organizations never face permanent data loss—even in the most demanding cloud environments.

Elevate your approach to asset management by transforming complexity into actionable capability. Our cyber asset analysis platform equips security teams with comprehensive insight into their assets, contextual information, and the risks inherent to their attack surface. With JupiterOne, organizations can shift from the challenges of asset visibility to harnessing it as a powerful advantage. This transition not only enhances security posture but also fosters a proactive approach to managing vulnerabilities.

LuxSci is dedicated to ensuring the safety of personal information while effectively safeguarding global communications. The company focuses on delivering web and email communication services that adhere to HIPAA regulations. LuxSci develops highly secure and tailored enterprise-level environments and solutions, empowering businesses to meet their unique operational and security requirements effectively. Among the offerings are services like Secure Email, Web, and Forms, which are designed to enhance data protection and facilitate compliance. In addition, LuxSci continuously evolves its services to adapt to the changing landscape of digital security.

AD360 is a comprehensive identity management solution that oversees user identities, regulates resource access, enforces security measures, and guarantees compliance with regulations. With its user-friendly interface, AD360 simplifies the execution of all IAM tasks. This solution is compatible with Windows Active Directory, Exchange Servers, and Office 365, providing a versatile platform for managing identities. Users can select from various modules tailored to their needs, facilitating the resolution of IAM challenges across hybrid, on-premises, and cloud environments. From a single console, you can efficiently provision, modify, and deprovision accounts and mailboxes for numerous users simultaneously. This capability extends to managing accounts across Exchange servers, Office 365, and G Suite. Additionally, the platform supports bulk provisioning of user accounts by utilizing customizable templates for user creation and allows for easy data import from CSV files, making the process even more streamlined. Overall, AD360 is designed to enhance productivity and security in identity management.

Hushmail enhances the security of your emails, web forms, and electronic signatures to ensure client confidentiality. Known for its security and HIPAA compliance, it has garnered trust among healthcare professionals globally. The setup process is straightforward, allowing you to send your first encrypted email instantly and create a secure online intake form in just a few minutes. Hushmail functions like standard email accounts while incorporating advanced security features to safeguard your information. You can send and receive encrypted messages through both web and iPhone applications. Additionally, your account can be accessed via Outlook, Apple Mail, or Android devices, making it convenient to manage your communications. Transitioning your forms to an online platform takes mere minutes with Hush™ Secure Forms, which serves as a secure substitute for traditional paper forms and offers instant online signing capabilities for your most critical documents. Switching from traditional pen and paper to e-signatures has never been simpler or more efficient. This streamlined process enhances productivity and ensures that client data remains protected at all times.

In just a matter of minutes, you can collect an extensive array of evidence by utilizing a variety of plugins tailored to comply with different frameworks like SOC 2, PCI, ISO, and SOX ITGC, in addition to bespoke internal audits, ensuring that your compliance requirements are effortlessly met. The system efficiently consolidates and structures relevant information into reliable and standardized evidence, enhancing visibility for improved teamwork. Not only is our solution quick and intuitive, but you can also start your free trial immediately. Bid farewell to monotonous compliance processes and welcome a SaaS platform that automates the evidence collection process while evolving with your business. For the first time, enjoy ongoing visibility into your compliance status and track audit activities in real time. With Anecdotes' state-of-the-art audit platform, you can provide your clients with an exceptional audit experience and redefine industry standards. This groundbreaking method guarantees that you maintain a competitive edge in compliance management, simplifying the task of meeting regulatory requirements and fostering a proactive compliance culture. Additionally, our platform's flexibility allows organizations to adapt to changing regulations with ease, ensuring sustained compliance over time.

Imagine conducting an audit free of conflict and managing compliance without any turmoil—this is precisely what we offer. Your preferred information-security standards, such as SOC 2, ISO 27001, and PCI DSS, can now be approached with ease and confidence. No matter the complexity of your needs, whether it’s urgent compliance for an upcoming agreement or navigating multiple frameworks as you enter new markets, we are here to assist you. We facilitate a swift start, catering to those who are either new to the compliance landscape or looking to refresh outdated processes. This way, your team can concentrate on strategic growth and innovation rather than getting bogged down by exhaustive evidence collection. With Thororpass, you can navigate your audit seamlessly from start to finish, ensuring there are no gaps or unexpected challenges. Our dedicated auditors are always available to provide the necessary guidance and can leverage our platform to create strategies that are resilient and sustainable for the future. Additionally, we believe that a streamlined compliance approach can empower your organization to thrive in a competitive environment.