List of the Top 6 Laboratory Information Systems (LIS) for Mac in 2025

The Avalon Laboratory System is an advanced and HIPAA-compliant platform tailored to oversee the production and billing needs of clinical, esoteric, and toxicology laboratories. Developed by Computer Service & Support (CSS), this modular laboratory information system provides a comprehensive suite of features aimed at automating reference laboratories. Additionally, it encompasses various modules for areas such as microbiology, pain management, toxicology, scheduling, remote laboratory operations, SQL access, and electronic medical records management. Beyond these functionalities, the system also integrates pharmacogenomics and revenue cycle management capabilities, making it a robust solution for modern laboratory challenges. This multifaceted approach ensures that labs can operate efficiently while adhering to regulatory standards.

Introducing an economical cloud-based Laboratory Information System (LIS) that's ideal for emerging laboratories! Subscriptions begin at just $250 a month, which includes three analyzer interfaces and unlimited user access. Our suite ensures CLIA compliance, simplifying adherence to regulatory standards. The user-friendly application can be set up within a day, and web-based training is readily available to assist users. This LIS is customizable to suit your specific analyzer and workflow needs. Additionally, our HIPAA-compliant mobile application facilitates patient registration, test ordering, and results notification. Our diverse clientele includes a variety of medical specialists and practice types, such as: My Doctor, LLC in Ohio, our inaugural client, a family practice; ABC Pediatrics in North Carolina, a pediatric clinic with ten physicians; Auspicious Lab in Texas, a toxicology commercial lab; Battelle Institute in Ohio, an applied science research facility; Children’s Healthcare of Atlanta in Georgia, where we link ten remote clinics to the main hospital system; Columbus LTACH in New Jersey, a hospital lab operating 26 analyzers; and the National Clinical Pathology Lab in Arkansas, the largest laboratory under the Federal Drug Administration. Furthermore, we proudly serve Next Oncology across the United States, a national chain focused on oncology and clinical trials.

LIS 365 is a comprehensive laboratory information system (LIS) designed to efficiently record, manage, and store data pertinent to medical and clinical laboratories. The most effective LIS software can facilitate the sending of laboratory test orders to various instruments, monitor those orders, and document the resulting data. Utilizing LIS software not only aids in automating workflows but also enhances record-keeping processes. Although it may not necessarily reduce time spent on tasks, it significantly alleviates the effort required from laboratory personnel. LIS365 empowers laboratories to boost their revenues while enhancing customer loyalty. Our solutions help laboratories enhance operational efficiency, optimize workflows, and prioritize both patient safety and satisfaction. Typical functionalities of a laboratory information system include Sample Management, Workflow management, and comprehensive reporting capabilities, which are essential for modern laboratory operations. In addition to these features, an effective LIS can also provide advanced analytics to support informed decision-making.

The LigoLab Laboratory Operating Platform™, which is a robust enterprise-level solution, encompasses various modules such as Accounts Payable (AP), Clinical Pathology (CP), Molecular Diagnostics (MDx), and Revenue Cycle Management (RCM), while also accommodating Direct-to-Consumer services. This versatility enhances the competitive edge of laboratories, enabling them to expand their operations and increase profitability. Within the RCM module, seamless integration with the Laboratory Information System (LIS) facilitates the automation of ICD/CPT coding, initiating the billing process right from the ordering stage and incorporating essential elements like verification, eligibility checks, and claim scrubbing. As a result, this comprehensive approach boosts claim submissions and revenue while significantly reducing the likelihood of claim denials. Additionally, TestDirectly serves as a patient engagement portal that empowers laboratories and collection sites to optimize their workflows related to collection, testing, and reporting. By streamlining these processes, it minimizes friction and the potential for errors associated with manual tasks and paperwork, ultimately enhancing operational efficiency. This advancement in technology not only benefits laboratories but also improves the overall patient experience in managing their health information.

The eHAT, or Electronic Healthcare Administrative Tool, is a flexible and web-based hospital information system designed to function without the limitations of specific platforms and is constructed using open-source technologies. This extensive system boasts 40 unique modules aimed at enhancing administrative, operational, revenue, and clinical workflows within healthcare facilities. Specifically designed for large, multi-specialty, and enterprise-level hospitals, eHAT Enterprise provides a comprehensive solution for various hospital management requirements. Furthermore, the eHAT Laboratory Information System boosts laboratory efficiency by automating tasks that were once performed manually. Covering the entire spectrum of lab activities—from sample collection through to reporting—this software effectively manages the recording, organization, storage, and tracking of vital information. To facilitate accurate tracking, we utilize barcodes to generate and update audit logs, ensuring a meticulous chain of custody that clearly indicates the location of samples at each phase of their journey. In summary, eHAT not only enhances the workflow of hospital operations but also leads to significant improvements in the precision and reliability of laboratory processes while providing a user-friendly interface for medical staff.

AP Easy Advanced is recognized as the leading on-premise laboratory information system specifically designed for the unique workflows of anatomic pathology. This innovative system prioritizes user experience, making it straightforward to master while maintaining a powerful and scalable framework. A key highlight of AP Easy Advanced is its integrated Provider Portal, which facilitates online order placements and allows laboratory clients to effortlessly access their reports. Furthermore, it features a patient portal that enables individuals to view their results and engage in secure communication with laboratory staff via messaging. The system seamlessly interfaces with electronic medical records, billing software, and lab instruments, thereby optimizing operations and reducing the likelihood of data entry errors. In addition, AP Easy Advanced includes customizable report templates, catering to the specific needs of various laboratories. With its adaptability, this system serves both large and small labs, offering flexible pricing structures such as transactional per-case costs or fixed monthly fees to meet the diverse needs of its users. Ultimately, AP Easy Advanced aims to boost laboratory productivity and elevate client satisfaction through its extensive range of functionalities, ensuring that laboratories can operate more effectively than ever before. This commitment to excellence positions AP Easy Advanced as an invaluable asset in the field of anatomic pathology.