List of the Top 8 Safety Data Sheet (SDS) Software for Mac in 2025

SafetyCulture is a mobile-centric operations platform designed to equip users with the knowledge, tools, and processes necessary for ensuring safety, achieving elevated standards, and fostering continuous improvement, providing a more efficient way to operate. Initially launched as a digital checklist application, it has since transformed into a comprehensive platform that facilitates inspections, addresses and resolves issues, manages assets, and supports on-the-move team training, enhancing overall productivity and safety practices. This evolution reflects a commitment to innovation and adaptability in the ever-changing landscape of workplace safety and efficiency.

EHS management software is crafted to streamline intricate business challenges. Our deployments are quicker, more economical, and yield higher success rates compared to conventional enterprise software systems. The true advantage of our solution lies not in the software itself, but in its capacity to assist you in accomplishing your tasks and meeting objectives across various departments, locations, and even continents. Our cloud-based solutions are user-friendly enough for frontline staff while being advanced enough to enable you to execute global, top-tier programs straight away. VelocityEHS has established itself as a reliable provider for managing risks, addressing industrial hygiene and environmental issues, as well as handling hazards and incidents. We uniquely offer MSDSonline for chemical management, along with Humantech's solutions for industrial and office ergonomics. With a customer base exceeding 18,000 worldwide, we have earned the trust of organizations seeking effective resolutions to their complex compliance challenges. Our commitment to innovation and excellence ensures that we continually adapt to meet the evolving needs of our clients.

Since 1999, we have been providing our clients with the most extensive chemical management solutions on the market, developed in collaboration with both our customers and leading industry experts. Our innovative cloud-based platform, iChemistry, serves users across the entire chemical management supply chain. This software is specifically designed to help you oversee environmental, health, and safety performance, ensuring compliance, minimizing risks, and improving profitability. It facilitates the generation and distribution of safety sheets, which are essential for recognizing potential hazards, preventing accidents, and reducing workplace risks. Moreover, it guarantees compliance with regulatory requirements such as REACH and GHS, fostering sustainability through initiatives aimed at reducing hazardous materials. By enhancing efficiency and control, iChemistry empowers organizations to utilize their time and resources more effectively. Additionally, our comprehensive SDS service grants access to one of Europe's largest databases of safety data sheets, with all documents digitized for quick retrieval of vital information. This ensures that you have the latest and most thorough safety information readily available, further boosting workplace safety and adherence to regulations. Ultimately, our commitment to innovation and client collaboration allows us to continually improve our offerings and better serve the needs of our clients.

Vector EHS Management seamlessly integrates all aspects of safety into a single, user-friendly platform. With our customizable system, you can oversee your complete environmental health and safety program, allowing for significant time savings and enhanced productivity within your safety department. The Vector EHS platform empowers you to efficiently manage your entire EHS program, ultimately leading to improved operational effectiveness. Our intuitive EHS software caters to organizations of all sizes, from multinational corporations to small local enterprises, enabling them to monitor, manage, and adhere to health, safety, and environmental regulations. Designed to fulfill the requirements of some of the most vital industries globally, Vector EHS also offers top-notch customer support that collaborates with you to tailor the software to fit your unique needs. This personalized assistance ensures that you can maximize the benefits of our software in your specific operational context.

EHS Insight is a comprehensive environmental, health, and safety management platform that enables organizations to maintain compliance throughout their operations. Not only is EHS Insight cost-effective, but it also boasts a straightforward setup process. The platform equips companies with essential tools for handling incidents, conducting audits, managing inspections, meeting compliance requirements, and implementing corrective measures. Furthermore, EHS Insight delivers outstanding support to businesses both during the initial software rollout and in the subsequent stages of utilization, ensuring that users can fully leverage its features for ongoing success. This commitment to customer service sets EHS Insight apart in the market.

CHEMDOX® software provides comprehensive assistance to regulatory professionals in managing hazardous materials effectively. It encompasses various functions such as chemical management, authoring of Safety Data Sheets (SDS/MSDS), translation of Safety Data Sheets, hazard labeling, ensuring compliance with GHS standards, and distribution of Safety Data Sheets. Moreover, CHEMDOX® guarantees high-quality classifications backed by robust regulatory content, while also featuring classification calculators for all applicable regulations. The software streamlines numerous tasks related to hazardous materials management, leveraging database support to enhance efficiency and accuracy. By integrating these features, CHEMDOX® not only simplifies regulatory compliance but also empowers users to maintain safety and adhere to legal requirements seamlessly.

ExESS® provides a comprehensive platform for the creation and distribution of safety data sheets that aligns with global regulatory requirements. Built on the flexible and scalable Microsoft .NET framework, ExESS is user-friendly and can be installed on personal computers, operated through extensive corporate networks, or accessed via cloud platforms. Additionally, it incorporates various national classifications, including Austria's VbF, Germany's BetrSichV, Störfallverordnung, and WGK, as well as VOC regulations for the EU, US, and Swiss VOCV, along with Denmark's MAL and the American NFPA and HMIS standards. In addition, Lisam offers information on occupational exposure limits, biological limit values, and compliance with SEVESO regulations. The classification feature in ExESS allows users to delve into the calculations and data sources that inform the final classification, thereby promoting transparency and accuracy in compliance efforts. This all-encompassing tool not only simplifies the safety data management process but also deepens the user's comprehension of safety regulations. Ultimately, ExESS® stands out as an essential resource for organizations seeking to enhance their compliance practices and improve safety data management efficiency.

We enhance global safety, promote sustainability, and boost productivity. Our software harnesses data from various sources to assist businesses in making informed strategic decisions aimed at reducing risk. This approach is referred to as Integrated Risk Management 4.0 (IRM 4.0). Our track record of success stems from the fact that we have consistently avoided encountering these challenges. Sphera's solutions for Environment, Health, Safety & Sustainability offer comprehensive risk management on a unified platform that can be tailored to fulfill both daily operational and long-term strategic EHS&S objectives. Furthermore, Sphera's Operational Risk Management Solutions empower organizations to establish a cohesive strategy that fosters Operational Excellence across the entire enterprise. In addition, our Product Stewardship Solutions blend top-tier resources and extensive content, enabling compliance while streamlining and automating all facets of a product’s lifecycle, ultimately leading to improved efficiency and effectiveness. By leveraging these innovative solutions, businesses are better equipped to navigate the complexities of risk management in today's dynamic environment.