List of the Top 12 Safety Data Sheet (SDS) Software for Windows in 2025

SafetyCulture is a mobile-centric operations platform designed to equip users with the knowledge, tools, and processes necessary for ensuring safety, achieving elevated standards, and fostering continuous improvement, providing a more efficient way to operate. Initially launched as a digital checklist application, it has since transformed into a comprehensive platform that facilitates inspections, addresses and resolves issues, manages assets, and supports on-the-move team training, enhancing overall productivity and safety practices. This evolution reflects a commitment to innovation and adaptability in the ever-changing landscape of workplace safety and efficiency.

Chemical Safety offers an extensive range of software applications focused on safety and environmental management. Among its many features are GHS labeling, safety data sheets, tracking chemical inventories, and managing hazardous waste effectively. This comprehensive suite is designed to enhance compliance and streamline safety processes for various industries.

EHS management software is crafted to streamline intricate business challenges. Our deployments are quicker, more economical, and yield higher success rates compared to conventional enterprise software systems. The true advantage of our solution lies not in the software itself, but in its capacity to assist you in accomplishing your tasks and meeting objectives across various departments, locations, and even continents. Our cloud-based solutions are user-friendly enough for frontline staff while being advanced enough to enable you to execute global, top-tier programs straight away. VelocityEHS has established itself as a reliable provider for managing risks, addressing industrial hygiene and environmental issues, as well as handling hazards and incidents. We uniquely offer MSDSonline for chemical management, along with Humantech's solutions for industrial and office ergonomics. With a customer base exceeding 18,000 worldwide, we have earned the trust of organizations seeking effective resolutions to their complex compliance challenges. Our commitment to innovation and excellence ensures that we continually adapt to meet the evolving needs of our clients.

GHSAuth, created by Mar-Kov Computer Systems, is an all-in-one solution for generating Safety Data Sheets (SDS) and Safety Labels that adhere to the Global Harmonization Standard (GHS) aimed at chemical manufacturers. This software provides Environmental Health and Safety (EH&S) professionals with the tools to effectively manage and organize SDS documents, access a comprehensive library of hazard codes and precautionary statements, oversee SDS revisions, and track changes, among other functionalities. There are both a free version and a premium option available, which are tailored to meet varying user requirements. Furthermore, GHSAuth is specifically designed to improve safety and compliance procedures within organizations that handle hazardous substances, ensuring a more streamlined and secure workflow. By utilizing this software, companies can significantly reduce the risk associated with chemical management while promoting a culture of safety.

Create your own OSHA-compliant Safety Data Sheets (SDSs) that adhere to GHS standards and can be generated with just one click, resulting in an editable format suitable for word processors. Rather than spending money on hiring a consultant for a handful of SDSs, consider investing in an SDS generator that allows for the affordable creation of SDSs for all your products. Additionally, this program features a tool for generating GHS labels required by OSHA, further bolstering your compliance efforts. For users looking for more capabilities, there is an optional inventory and production management feature that aids in preparing batches and efficiently tracking raw materials and finished products. Offered as a one-time purchase, the software also provides annual upgrades to maintain its relevance. You can create an unlimited number of SDSs without incurring any per-page or document fees, and the layout is thoughtfully organized with tabs for each section and subsection of the SDS. With a user-friendly interface that highlights important fields with color-coded titles, navigation becomes seamless, and the tool allows for an unlimited number of mixture components when adding ingredients that are mixtures themselves, ensuring a thorough and detailed approach to safety documentation. Not only does this software streamline the SDS creation process, but it also ensures peace of mind by incorporating comprehensive compliance functionalities, making it an invaluable resource for any business involved in handling hazardous materials. Moreover, the intuitive design empowers users to focus on safety while minimizing the complexities often associated with regulatory documentation.

Vector EHS Management seamlessly integrates all aspects of safety into a single, user-friendly platform. With our customizable system, you can oversee your complete environmental health and safety program, allowing for significant time savings and enhanced productivity within your safety department. The Vector EHS platform empowers you to efficiently manage your entire EHS program, ultimately leading to improved operational effectiveness. Our intuitive EHS software caters to organizations of all sizes, from multinational corporations to small local enterprises, enabling them to monitor, manage, and adhere to health, safety, and environmental regulations. Designed to fulfill the requirements of some of the most vital industries globally, Vector EHS also offers top-notch customer support that collaborates with you to tailor the software to fit your unique needs. This personalized assistance ensures that you can maximize the benefits of our software in your specific operational context.

EHS Insight is a comprehensive environmental, health, and safety management platform that enables organizations to maintain compliance throughout their operations. Not only is EHS Insight cost-effective, but it also boasts a straightforward setup process. The platform equips companies with essential tools for handling incidents, conducting audits, managing inspections, meeting compliance requirements, and implementing corrective measures. Furthermore, EHS Insight delivers outstanding support to businesses both during the initial software rollout and in the subsequent stages of utilization, ensuring that users can fully leverage its features for ongoing success. This commitment to customer service sets EHS Insight apart in the market.

Streamline your approach to chemical management by embracing our intuitive SDS software solution, which allows you to effortlessly manage your chemicals and access a current SDS library online. With sdsBinders, the cumbersome nature of paper documents becomes a thing of the past, as you transition to a seamless online system that provides immediate access to critical safety data sheets and chemical safety information. This essential information empowers your team with the understanding needed to ensure their health and safety, creating a solid foundation for responsible chemical use and compliance with regulations. You can focus on other important tasks while we handle your SDS management, enjoying the convenience of 24/7 access through a personalized web portal that guarantees your safety data sheets are always updated and in line with GHS regulatory requirements. Our robust SDS management software not only monitors your SDS library but also sends you alerts for any modifications or potential concerns, enhancing the security and reliability of your chemical safety practices. By simplifying your SDS management, we provide a comprehensive and efficient solution that meets all your needs and expectations, ensuring your operations run smoothly and safely. Transitioning to this modern system will not only improve compliance but also foster a culture of safety within your organization.

CHEMDOX® software provides comprehensive assistance to regulatory professionals in managing hazardous materials effectively. It encompasses various functions such as chemical management, authoring of Safety Data Sheets (SDS/MSDS), translation of Safety Data Sheets, hazard labeling, ensuring compliance with GHS standards, and distribution of Safety Data Sheets. Moreover, CHEMDOX® guarantees high-quality classifications backed by robust regulatory content, while also featuring classification calculators for all applicable regulations. The software streamlines numerous tasks related to hazardous materials management, leveraging database support to enhance efficiency and accuracy. By integrating these features, CHEMDOX® not only simplifies regulatory compliance but also empowers users to maintain safety and adhere to legal requirements seamlessly.

ExESS® provides a comprehensive platform for the creation and distribution of safety data sheets that aligns with global regulatory requirements. Built on the flexible and scalable Microsoft .NET framework, ExESS is user-friendly and can be installed on personal computers, operated through extensive corporate networks, or accessed via cloud platforms. Additionally, it incorporates various national classifications, including Austria's VbF, Germany's BetrSichV, Störfallverordnung, and WGK, as well as VOC regulations for the EU, US, and Swiss VOCV, along with Denmark's MAL and the American NFPA and HMIS standards. In addition, Lisam offers information on occupational exposure limits, biological limit values, and compliance with SEVESO regulations. The classification feature in ExESS allows users to delve into the calculations and data sources that inform the final classification, thereby promoting transparency and accuracy in compliance efforts. This all-encompassing tool not only simplifies the safety data management process but also deepens the user's comprehension of safety regulations. Ultimately, ExESS® stands out as an essential resource for organizations seeking to enhance their compliance practices and improve safety data management efficiency.

The OSHA Safety Manager is a holistic platform aimed at simplifying the documentation of injuries and accidents while simultaneously improving safety protocols. Leveraging the framework of Employee Views HRIS, it integrates specific safety functionalities to meet this goal. Key features include an injury log management tool, which facilitates the creation of OSHA 101/200 forms and allows users to monitor other incidents that might not necessitate formal documentation. Users can generate the 200 form with complete details or opt for a version that excludes personal information, making it suitable for signatures and public dissemination. An intuitive automated flowchart assists users in determining which incidents should be officially recorded. Additionally, the system offers a comprehensive Hazardous Materials Inventory and manages vendor MSDS (Material Safety Data Sheets) effectively. This centralized design enhances both accuracy and coordination, ensuring that all relevant information is readily available in one place and kept up-to-date. Users benefit from the flexibility to access details in multiple formats, promoting clarity and ease of use within the platform. The system also retains a robust historical archive for every log entry, which is accessible in its entirety for thorough examination. This feature not only improves record-keeping but also strengthens compliance initiatives, making it an invaluable resource for organizations focused on safety management. Ultimately, the OSHA Safety Manager supports a culture of safety by enabling proactive risk management and fostering a commitment to employee well-being.

We enhance global safety, promote sustainability, and boost productivity. Our software harnesses data from various sources to assist businesses in making informed strategic decisions aimed at reducing risk. This approach is referred to as Integrated Risk Management 4.0 (IRM 4.0). Our track record of success stems from the fact that we have consistently avoided encountering these challenges. Sphera's solutions for Environment, Health, Safety & Sustainability offer comprehensive risk management on a unified platform that can be tailored to fulfill both daily operational and long-term strategic EHS&S objectives. Furthermore, Sphera's Operational Risk Management Solutions empower organizations to establish a cohesive strategy that fosters Operational Excellence across the entire enterprise. In addition, our Product Stewardship Solutions blend top-tier resources and extensive content, enabling compliance while streamlining and automating all facets of a product’s lifecycle, ultimately leading to improved efficiency and effectiveness. By leveraging these innovative solutions, businesses are better equipped to navigate the complexities of risk management in today's dynamic environment.