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What is Genome Analysis Toolkit (GATK)?

Developed by the Data Sciences Platform at the Broad Institute, this all-encompassing toolkit offers a broad spectrum of features that focus largely on variant discovery and genotyping. It boasts a powerful processing engine along with high-performance computing capabilities, making it suitable for handling projects of any size. The GATK is recognized as the gold standard for identifying SNPs and indels in germline DNA as well as RNA sequencing data. Its functionalities are expanding to include detection of somatic short variants, as well as tackling copy number variations (CNV) and structural variations (SV). In addition to the primary variant callers, the GATK features a variety of utilities designed for performing related tasks, such as processing and ensuring the quality of high-throughput sequencing data, and it is complemented by the renowned Picard toolkit. Initially tailored for exome and whole genome data produced by Illumina sequencing technologies, these tools exhibit enough flexibility to adapt to various other sequencing technologies and study designs. As the field of genomics continues to advance, the GATK's versatility guarantees its ongoing relevance in a wide range of genomic research projects, ensuring that it remains a pivotal resource for scientists exploring genetic variations.

What is CZ CELLxGENE Discover?

Select two customized cell groups by leveraging metadata to identify their most distinctly expressed genes. Use the vast repository of millions of cells from the integrated CZ CELLxGENE database for comprehensive analysis. Engage in dynamic examinations of datasets to explore how gene expression patterns are shaped by spatial, environmental, and genetic factors through an intuitive no-code interface. This approach allows researchers to gain insights into existing datasets or utilize them as a springboard to uncover novel cell subtypes and states. Census enables access to any tailored segment of standardized cell data within the CZ CELLxGENE, with options for exploration in both R and Python environments. Immerse yourself in an interactive encyclopedia that features over 700 cell types, complete with detailed definitions, marker genes, lineage details, and related datasets all accessible in a single platform. In addition, researchers can browse and acquire an extensive array of standardized data collections, alongside more than 1,000 datasets that illuminate the functions of both healthy mouse and human tissues, significantly enhancing the study of cellular biology. This resource serves as an invaluable tool for scientists striving to deepen their understanding of cellular dynamics and gene expression, ultimately driving innovation in the field. Furthermore, the user-friendly interface promotes collaborative efforts among researchers, fostering a community of shared knowledge and discoveries.

Media

Media

Integrations Supported

Docker
Python
R

Integrations Supported

Docker
Python
R

API Availability

Has API

API Availability

Has API

Pricing Information

Free
Free Trial Offered?
Free Version

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

Broad Institute

Company Location

United States

Company Website

gatk.broadinstitute.org/hc/

Company Facts

Organization Name

CZ CELLxGENE

Company Location

United States

Company Website

cellxgene.cziscience.com

Categories and Features

Categories and Features

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