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What is SILCS?

Site-Identification by Ligand Competitive Saturation (SILCS) generates three-dimensional representations called FragMaps, which depict the interactions of various chemical functional groups with a designated target molecule. By uncovering the intricacies of molecular dynamics, SILCS provides essential tools that facilitate the refinement of ligand scaffolds, offering both qualitative and quantitative perspectives on binding sites, which ultimately aids in optimizing the drug design workflow. This methodology utilizes a selection of small molecule probes, each possessing a variety of functional groups, along with explicit solvent modeling and the flexibility of the target molecule to effectively map protein targets. Moreover, the technique empowers researchers to visualize beneficial interactions with the target macromolecule, allowing for a more informed design process. Armed with these insights, scientists can strategically engineer enhanced ligands with functional groups positioned for maximum efficacy. The pioneering approach of SILCS marks a noteworthy leap forward in the realm of medicinal chemistry, opening new avenues for drug discovery and development. Through its advanced analytical capabilities, SILCS not only enhances understanding but also drives innovation in therapeutic design.

What is Chemical Computing Group?

Chemical Computing Group (CCG) is recognized for its commitment to providing collaborative scientific support. With operations spanning North America, Europe, and Asia, our team of PhD-level scientists works closely with clients to offer tailored assistance, practical training, and specialized scientific advice on various projects. Moreover, CCG is dedicated to the continuous advancement of cutting-edge technologies, drawing on the skills of mathematicians, scientists, and software engineers, while also forming scientific partnerships with customers to improve research results. This teamwork-driven strategy not only enhances client satisfaction but also cultivates a culture of creativity and innovation within the company, ultimately leading to more successful outcomes for all stakeholders involved.

Media

Media

Integrations Supported

Additional information not provided

Integrations Supported

Additional information not provided

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

SilcsBio

Date Founded

2012

Company Location

United States

Company Website

silcsbio.com/software/

Company Facts

Organization Name

Chemical Computing Group

Date Founded

1994

Company Location

Canada

Company Website

www.chemcomp.com/Products.htm

Categories and Features

Categories and Features

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