List of the Top 11 Autonomous Endpoint Management (AEM) Software for Mac in 2026

NinjaOne streamlines the most challenging aspects of IT management, serving over 20,000 IT teams with enhanced capabilities. By delivering in-depth insights into endpoints, strong security protocols, and a unified control system, NinjaOne increases operational efficiency, protects sensitive information, and reduces IT costs. This all-encompassing platform provides a diverse set of tools for managing and securing endpoints, such as patch management, mobile device supervision, software deployment, remote assistance, backup solutions, and additional features, all made possible through its wide-ranging IT and security integrations. With its ability to adapt to various IT environments and needs, NinjaOne stands out as a vital resource for modern IT teams.

Atera is a comprehensive IT management solution that integrates remote monitoring and management (RMM), helpdesk services, and ticketing, all enhanced by Action AI™ to significantly increase efficiency for organizations of any size. Experience the benefits of Atera with a free trial today!

ManageEngine's Endpoint Central, which was previously known as Desktop Central, serves as a comprehensive Unified Endpoint Management Solution that oversees enterprise mobility management. This solution encompasses all aspects of mobile app and device management, in addition to client management for various endpoints, including mobile devices, laptops, tablets, servers, and other computing machines. With ManageEngine Endpoint Central, users can streamline and automate numerous desktop management activities, such as software installation, patching, IT asset management, imaging, and operating system deployment, thereby enhancing operational efficiency across the organization. This tool is particularly beneficial for IT departments looking to maintain control over their diverse technology environments.

Atera IT Autopilot is an advanced AI-driven autonomous IT support agent designed to help IT teams overcome challenges caused by increasing ticket volumes, shrinking staff, and growing demands for immediate resolution. By automating routine IT support and complex troubleshooting tasks, it enables employees to self-resolve issues, significantly cutting down on helpdesk backlogs and freeing IT staff to focus on strategic projects. The platform delivers instant, human-like assistance through a variety of channels including user portals, email, Slack, and Microsoft Teams, guaranteeing 24/7 support coverage with a remarkable first response time of 0.1 seconds. IT Autopilot also offers smart assistance features, device and cloud support, whitelisted software management, and escalates more difficult problems to technicians as needed. Comprehensive reporting and analytics empower IT teams with insights to monitor performance and optimize workflows. With integrations available for essential IT functions like backup, security, and network monitoring, the solution fits seamlessly into existing IT environments. IT Autopilot helps reduce IT workloads by up to 40%, saving technicians hours daily and mitigating burnout. Its autonomous operations ensure business continuity even outside traditional working hours, boosting overall productivity. The platform complies with governance frameworks and ethical standards to safeguard data and maintain responsible AI use. Ultimately, Atera IT Autopilot transforms IT support by combining AI efficiency with human oversight to deliver reliable, scalable, and continuous service.

Action1 transforms patch management by allowing organizations to swiftly identify and address vulnerabilities, achieving an impressive 99% success rate in patch deployment. Enhance your third-party patching processes, including bespoke software, through Action1’s proprietary Software Repository, expertly managed by security professionals, while also overseeing OS updates in a fully integrated system that ensures functional consistency. Real-time vulnerability detection enables immediate remediation by applying patches, eliminating outdated software, or consolidating documentation for vulnerabilities that are unpatchable through compensating controls. Improve network efficiency when deploying substantial software packages, up to 32Gb, simultaneously, and accelerate patch delivery with Action1’s innovative P2P Distribution technology. Recognized as the most user-friendly patch management solution available, Action1 can be set up within five minutes, allowing for immediate automation of patching through its straightforward interface. With its cloud-native architecture, Action1 is designed to scale infinitely and seamlessly supports both on-site and remote employee systems, servers, and cloud applications without the need for a VPN. As a pioneering patch management provider, Action1 has also become the first vendor to achieve SOC 2 and ISO certifications, further solidifying its commitment to security and reliability in patch management.

Iru AI is a next-generation, AI-native security and compliance platform designed to unify and automate enterprise protection in an increasingly complex digital landscape. Built from the ground up for the AI era, Iru integrates identity management, endpoint protection, and compliance automation within a single, context-aware system. Its proprietary Iru Context Model continuously interprets relationships between users, apps, and devices, enabling intelligent actions across authentication, threat detection, and audit workflows. The Identity module eliminates passwords with device-bound authentication, ensuring frictionless yet secure access to every enterprise app. The Endpoint suite consolidates management, detection, and vulnerability response into one lightweight agent, providing real-time visibility and cross-platform consistency. Meanwhile, the Compliance engine automates control mapping and evidence collection, reducing audit preparation time while maintaining continuous readiness. Unlike fragmented legacy tools, Iru’s unified approach minimizes security gaps, streamlines administration, and improves user experience across the organization. The platform’s scalability and AI automation have helped firms cut IT workloads in half while achieving stronger security postures and regulatory compliance. Trusted by global innovators like Airbus, Notion, McLaren, and BetterHelp, Iru is transforming how enterprises secure their digital ecosystems. With over 5,000 customers and top-tier ratings for usability and innovation, Iru empowers teams to focus on strategic growth rather than operational complexity.

Zirozen serves as a unified autonomous endpoint management platform that offers instant visibility and control over the entire IT ecosystem, which includes both network devices and cloud services, all accessible via an intuitive drag-and-drop interface. Its AI-powered engine continuously monitors for vulnerabilities, misconfigurations, missing patches, and unauthorized software, methodically prioritizing and mitigating risks based on their severity. Additionally, Zirozen simplifies patch and configuration management across various platforms with policy-driven scheduling, ensuring adherence to compliance standards like GDPR, HIPAA, and PCI-DSS, while also providing features for tracking software usage and managing licenses, monitoring file integrity, enforcing application restrictions, and identifying malicious activities. By achieving deep integration, Zirozen minimizes tool redundancy by merging security, asset, and inventory data into one comprehensive dashboard, while customized alerts and centralized reporting foster a proactive approach to security operations, drastically reducing the time needed to resolve issues. This all-encompassing functionality not only enables organizations to uphold a strong security posture but also improves overall operational efficiency significantly. Additionally, Zirozen’s adaptable nature allows organizations to scale their endpoint management efforts seamlessly as their IT environments evolve.

Automox operates in the cloud and is accessible worldwide. It streamlines the management of operating system and third-party patches, security settings, and custom scripts for both Windows and Mac systems through a unified interface. This enables IT and security operations teams to swiftly establish control and enhance visibility across virtual, on-premises, and remote endpoints, all while avoiding the need for costly infrastructure deployments. By simplifying these processes, Automox ensures that organizations can maintain robust security and compliance efficiently.

Splashtop's Autonomous Endpoint Management provides an automated solution for managing endpoints, specifically designed to aid IT teams in overseeing, securing, patching, and controlling devices remotely, all while minimizing manual involvement. This innovative approach offers instant insights into the health of devices, automates the patching for both operating systems and third-party applications, and maintains compliance in multi-location environments. With features like secure remote access and real-time patch management, it integrates seamlessly with platforms such as Microsoft Intune to quickly pinpoint and mitigate zero-day vulnerabilities. Centralized dashboards allow for a holistic overview of inventory, security metrics, and the status of endpoints, enabling IT teams to proactively tackle issues before they impact users, all while ensuring compliance with vital regulations like ISO/IEC 27001, SOC 2, GDPR, HIPAA, and PCI. Moreover, AEM simplifies standard operations, including patch deployment and system updates, which frees up IT staff from tedious tasks and allows them to concentrate on more sophisticated problems. As a result, this cutting-edge endpoint management solution not only boosts operational efficiency but also strengthens an organization’s security framework while facilitating a more agile response to emerging threats.

HCL BigFix serves as a cutting-edge AI Digital+ endpoint management platform that enhances employee experiences while automating infrastructure management with intelligence. This platform provides comprehensive solutions for securing and managing endpoints across nearly 100 operating systems, ensuring ongoing compliance with industry standards, and transforming vulnerability management through exceptional cybersecurity analytics. It stands as the singular solution capable of securing any endpoint across all clouds and industries. Additionally, HCL BigFix is unique in its ability to empower IT Operations and Security teams to fully automate the discovery, management, and remediation processes, whether in on-premise, virtual, or cloud environments, without being hindered by operating systems, location, or connectivity issues. Unlike traditional, complex tools that only cover a fraction of your endpoints and require extended periods for remediation, BigFix swiftly identifies and resolves endpoint issues, achieving over 98% success rates on initial patch attempts, thus setting a new standard in endpoint management efficiency.

Remedio stands as an innovative platform that utilizes artificial intelligence to autonomously oversee device posture by persistently detecting, tracking, and rectifying security misconfigurations and configuration drift within both enterprise IT and operational technology realms, with the primary goal of reducing the attack surface while maintaining compliance and enhancing endpoint security without disruption. It provides instantaneous insights regarding configuration weaknesses on devices running Windows, macOS, and Linux, as well as on cloud servers, and proactively applies safe, reversible remediation actions that enable security teams to effectively tackle vulnerabilities without hindering business operations. By streamlining the validation and enforcement of security policies, Remedio measures configurations against reputable security standards such as CIS, NIST, and MITRE frameworks, consistently reapplying these policies amid software updates, user alterations, and the deployment of new devices to maintain secure baselines. Furthermore, it offers centralized governance and management capabilities for Active Directory, Group Policy, MDM, and Intune settings, thereby granting organizations a thorough overview of their security posture. Additionally, this comprehensive strategy empowers organizations to remain agile while simultaneously fortifying their defenses against an ever-changing landscape of threats, ensuring they can proactively combat potential risks.