List of the Top 10 Endpoint Protection Software for Autotask PSA in 2026

Guardz is the unified cybersecurity platform built for MSPs. We consolidate the essential security controls, including identities, endpoints, email, awareness, and more, into one AI-native framework designed for operational efficiency. With an identity-centric approach, an elite threat hunting team, and 24/7 AI + human-led MDR, Guardz transforms cybersecurity from reactive defense into proactive protection.

NinjaOne bolsters endpoint security by implementing monitoring, patch management, and software controls. It utilizes automated notifications to detect unusual activities or unapproved applications. Consistent patch updates safeguard devices against potential vulnerabilities. Technicians can employ remote commands for immediate threat remediation. Additionally, backup capabilities offer further protection against ransomware attacks. Comprehensive reporting offers valuable insights into the security status of endpoints. With NinjaOne, endpoints are maintained in a secure and compliant state.

Enhance the security of your workforce with robust and user-friendly access solutions from Cisco Duo. Our cutting-edge access security framework is meticulously crafted to safeguard every user, device, and application, allowing you to concentrate on your core activities. Enjoy secure access for all users and devices across various environments and locations, ensuring peace of mind through complete device visibility and trust. This SaaS solution seamlessly protects all applications while being straightforward to deploy, scalable, and responsive to emerging threats. Duo's access security is essential for shielding applications from compromised credentials and devices, offering extensive coverage that aids in fulfilling compliance mandates. By integrating smoothly with applications, Duo delivers flexible, user-centric security that is easy to implement and administer. For administrators, users, and IT teams alike, this is a practical solution that benefits everyone involved. Essential features such as multi-factor authentication, dynamic device trust, adaptive authentication, and secure single sign-on play vital roles in your journey towards a zero-trust framework. Each of these components contributes to a comprehensive security strategy that evolves with your organization's needs.

Provide remote assistance to both client and internal systems through unattended access, enabling users to connect to their computers from afar. Whether you're new to remote support solutions or seeking a cost-effective alternative to pricier options, Splashtop Remote Support is an ideal choice. This top-tier remote support solution facilitates seamless access to your managed devices from any platform, ensuring you can connect anytime, backed by our rapid, high-definition connections. With Splashtop, remote management becomes efficient and user-friendly, enhancing productivity for both support teams and users alike.

Heimdal® Endpoint Detection and Response is our exclusive multi-faceted service that offers exceptional capabilities for prevention, threat hunting, and remediation. This service integrates the most cutting-edge threat-hunting technologies available, including Heimdal Next-Gen Antivirus, Heimdal Privileged Access Management, Heimdal Application Control, Heimdal Ransomware Encryption Protection, Heimdal Patch & Asset Management, and Heimdal Threat Prevention. With six modules functioning together harmoniously under a single platform and agent, Heimdal Endpoint Detection and Response provides comprehensive cybersecurity layers necessary for safeguarding your organization against both familiar and unfamiliar online and internal threats. Our advanced product enables rapid and precise responses to complex malware, ensuring that your digital assets are protected while also maintaining your organization's reputation. By consolidating these capabilities, we deliver an efficient solution that addresses the evolving challenges of cybersecurity effectively.

This EDR solution is designed to reveal the untapped capabilities of your network. Utilizing ESET's comprehensive Endpoint Protection Platform, this tool effectively identifies and manages endpoint security issues. It channels all relevant data to ESET Enterprise Inspector, which processes vast amounts of real-time information from endpoints. With impressive speed, it can pinpoint and resolve any security vulnerabilities within the network. ESET Enterprise Inspector features a distinctive reputation-based detection approach that remains unobtrusive for security personnel. For enhanced customization, users can easily modify all rules through XML. You also have the flexibility to develop new rules tailored to the specific requirements of your organization, including seamless integrations with SIEM systems. ESET's endpoint detection and response tool simplifies the management of false positives, allowing you to fine-tune detection sensitivity across various user groups or computer categories. By combining criteria such as file name, path, hash, command line, and signer, you can precisely adjust the conditions under which alerts are triggered, ensuring a tailored security approach. This level of customization empowers organizations to enhance their overall security posture effectively.

Acronis Cyber Protect offers reassurance by ensuring that your business is shielded against threats such as zero-day malware and ransomware, while also providing backup solutions and forensic analysis. With the rapid evolution of cyber threats, relying on basic data backup and cybersecurity measures is no longer sufficient to keep them at bay. Acronis provides comprehensive cyber protection that integrates cybersecurity, data backup, disaster recovery, and additional features to maintain the security of your essential data and systems. Many businesses find themselves relying on a convoluted mix of tools to protect against data loss and cyber threats, but this fragmented approach can create management challenges and leave vulnerabilities. In contrast, Acronis’ unified cyber protection offerings effectively secure complete workloads with improved efficiency and reduced complexity, allowing your team to prioritize protection and strategic initiatives instead of managing disparate solutions. Easily safeguard entire workloads without complications, as getting started with Acronis' cyber protection solutions is both straightforward and seamless. You can provision numerous systems with just a single click and oversee everything—from backup policies to vulnerability assessments and patch management—through a unified interface, streamlining your cybersecurity efforts.

ConnectWise Cybersecurity Management, which was previously known as ConnectWise Fortify, provides software and support services that enable Managed Service Providers (MSPs) to safeguard their clients' essential business assets. By offering round-the-clock threat detection, incident response, and tools for security risk assessments, these solutions simplify the process of creating a cybersecurity framework powered by MSPs, while also reducing the expenses related to continuous monitoring and support personnel. Consequently, MSPs can focus more on their core services without the added burden of cybersecurity complexities.

Kaseya VSA is a sophisticated remote monitoring and management (RMM) tool tailored for Managed Service Providers (MSPs) and IT organizations. This software encompasses a wide range of functionalities, including swift remote access, robust discovery features, reliable patch management, and extensive monitoring and security options, all within a single platform. Consequently, Kaseya VSA significantly boosts the productivity of IT personnel, enhances service reliability, and strengthens system security. It acts as a unified IT Management solution, designed not only to improve service delivery but also to revolutionize business operations. By optimizing workflows across multiple tools, Kaseya’s platform markedly increases the efficiency of IT teams, thereby promoting better service delivery and improving overall business productivity. Organizations can experience firsthand the reasons behind the trust placed in Kaseya VSA by numerous IT departments for managing and automating their entire IT infrastructure from one central hub. Ultimately, this platform provides organizations with the ability to deliver increased value while reducing service delivery costs. Kaseya VSA supplies IT departments with essential management resources to actively monitor their systems via an integrated interface, establishing itself as a vital partner in the field of IT management. Furthermore, the seamless integration of Kaseya VSA with existing workflows allows for a smoother transition and enhances user satisfaction across the board.

Rest assured that Covalence protects your endpoints, network, and cloud services through a cohesive platform. Elevate the capabilities of your cybersecurity team by leveraging immersive virtual environments crafted for training, evaluation, practice, competition, and skill enhancement. Partner with us to develop a distinctive cybersecurity solution that attracts customers, increases profit margins, and drives revenue growth. The endpoint agent, developed from years of cybersecurity knowledge, delivers immediate threat detection, thorough analysis, and proactive response capabilities. Covalence customizes its approach to cyber threats according to your organization's specific needs and response strategies. Users receive timely alerts with crucial details such as the nature of the threat, its severity, and the actions taken to mitigate it, ensuring clarity and control throughout incidents. This all-encompassing strategy not only strengthens your defenses but also builds trust among your clients regarding their safety. In today's rapidly changing digital landscape, it is essential to stay ahead of emerging threats, and Covalence is committed to providing the tools needed for success.