List of the Top 6 HIPAA Compliance Software for Microsoft SharePoint in 2026

Hyperproof is a compliance operations platform designed to help organizations replace reactive, manual audit prep with a continuous, well-managed program. Instead of running each regulatory framework as its own project, Hyperproof lets teams map a single control across 160-plus frameworks, so the evidence and testing already completed for one standard can count toward another, removing duplicate effort as new regulations come into scope. For business and compliance leaders, the value shows up in measurable operational gains. Customers point to a 70% lift in overall compliance productivity, close to $150K trimmed from yearly control-orchestration costs, and a 66% drop in the duplicative control work that piles up when frameworks aren't mapped together. On average, audit prep shrinks by roughly 350 hours annually. The platform's risk register gives risk owners across the business a shared place to document risks and treatment plans, giving leadership better visibility into where the organization stands at any given time rather than reconstructing that picture ahead of every audit. Hyperproof is also built to flex with organizational complexity, supporting companies with multiple business units or subsidiaries that need to scope compliance programs differently across entities rather than manage a single flat structure. Combined with integrations into commonly used business and IT systems, teams can keep compliance work embedded in their existing processes instead of managing it as a parallel, disconnected effort. Headquartered near Seattle and founded in 2018, Hyperproof is the compliance platform of choice for organizations such as Reddit, Fortinet, Appian, Outreach, and Thales as they professionalize compliance operations and reduce the resourcing burden of staying audit-ready. Best fit: compliance, risk, and operations leaders at mid-market and enterprise organizations managing regulatory complexity across multiple frameworks or business units.

With the trust of over 25 million users globally, Jotform serves as a comprehensive platform that enhances data gathering, automates workflows, and facilitates online sales without requiring any coding skills. Utilizing Jotform’s intuitive drag-and-drop Form Builder, companies can easily design personalized forms and surveys to gather leads, contact details, payments, appointments, and e-signatures. Users can select from a library of more than 10,000 templates tailored for various purposes, such as feedback forms or event registrations, or opt to create their own unique forms from the ground up. The platform’s sophisticated features, including conditional logic, autoresponders, and compatibility with over 200 integrations, significantly optimize operational processes. Moreover, Jotform's AI-driven Agents provide immediate customer support by assisting users during the form submission journey, addressing inquiries, and ensuring a seamless experience, which minimizes the reliance on manual support. With the addition of Jotform’s Store Builder, businesses can establish an online storefront to market products, services, and subscriptions, as well as collect donations and process payments through a wide array of over 30 payment gateways. Furthermore, tools like the Approvals feature, PDF Editor, and Report Builder empower organizations to convert gathered data into insightful actions and streamline workflows for enhanced productivity. This multifaceted approach makes Jotform a vital resource for businesses seeking to improve their operational efficiency and customer engagement.

Diplomat MFT by Coviant Software is a powerful, enterprise-ready managed file transfer solution designed for secure, automated delivery of sensitive data. It supports leading secure protocols including SFTP, FTPS, HTTPS, and AS2 which integrates seamlessly with platforms like AWS S3, Azure, Google Cloud, Oracle, SharePoint, Box, and Dropbox. Diplomat MFT includes built-in PGP encryption, IP access rules, threat intelligence scanning, and multi-factor authentication, features that help organizations maintain compliance with regulations like HIPAA, PCI/DSS, GLBA, GDPR, and DORA. If you're overwhelmed by compliance risks or face challenges with managing brittle scripts, it’s time for a better solution. Diplomat MFT eliminates uncertainty and gives you peace of mind. Start your free trial today.

Medsender offers a comprehensive automation solution for healthcare, featuring HIPAA-compliant faxing, emails, SMS, forms, and signatures, all effortlessly integrated into your electronic medical records (EMR) system. Utilizing cutting-edge artificial intelligence, it streamlines processes by securely managing incoming faxes through a cloud platform that sorts them automatically to the appropriate staff and patient charts. Patients benefit from an easy-to-use interface for filling out forms and sending notes, further enhancing communication and efficiency. With a simple one-click setup, there's no need for traditional fax machines, and Medsender's compatibility with all major EMRs, along with ongoing integration developments, ensures flexibility. Additionally, it can function independently of an EMR, allowing for versatile usage across various healthcare environments. By leveraging the latest AI advancements, we help you minimize repetitive tasks and unnecessary busy work, providing peace of mind. Currently, Medsender successfully handles over 5 million pages of patient data while maintaining an impressive uptime of over 99.9%. This commitment to reliability and efficiency makes Medsender an invaluable asset for healthcare providers seeking to enhance their operational workflows.

OpenText CloudAlly Backup offers a unified, cloud-native platform designed to protect SaaS environments from data loss due to user error, ransomware, sync corruption, malicious intent, and service outages. It provides automated or on-demand immutable backups for Microsoft 365, Google Workspace, Salesforce, Box, Dropbox, and other major cloud services, ensuring full recovery across emails, files, metadata, calendars, drives, and collaboration tools. Organizations can store data in CloudAlly’s secure AWS S3 infrastructure across nine global data centers or use their own cloud accounts for maximum control. Unlimited retention, granular recovery tools, and 1-click restore capabilities simplify retrieval of individual items, entire accounts, or full system snapshots. Powerful features such as anomaly detection, keyword search, sandbox seeding, and data comparison strengthen security and productivity for large or distributed teams. CloudAlly’s security architecture includes AES-256 encryption, strict access controls, MFA, HIPAA and GDPR compliance, and ISO certifications, making it one of the most trusted SaaS backup solutions on the market. The MSP-friendly Partner Portal offers centralized oversight, subscription management, reporting, and white-label branding to support scalable service delivery. For SMBs and enterprises alike, CloudAlly delivers cost-effective protection with pay-as-you-go pricing and a zero-tier licensing model. Customers benefit from a proven track record, protecting billions of files monthly and completing thousands of backups per day. Ultimately, CloudAlly ensures that organizations never face permanent data loss—even in the most demanding cloud environments.

ZenGRC is a cutting-edge Governance, Risk, and Compliance platform that simplifies the complex processes involved in risk management and regulatory compliance. With its intuitive interface, ZenGRC allows businesses to centralize all risk and compliance data in one secure system, making it easier for teams to manage, track, and report on compliance efforts. The platform’s AI-driven automation capabilities enhance efficiency by automating tasks and providing actionable insights, allowing businesses to make informed decisions quickly. ZenGRC also integrates effortlessly with over 30 leading systems, ensuring smooth workflows and enabling a comprehensive risk management strategy. Recognized for its innovation with the ISACA Global Innovation Award in 2024, ZenGRC offers flexible, customizable frameworks that adapt to any organization’s unique needs. With certifications in GDPR and SOC, ZenGRC ensures that customer data remains secure and compliant. It’s the ideal solution for businesses looking to optimize their GRC processes and maintain a proactive stance in managing risks and compliance.