List of the Top 25 Manufacturing Execution Systems for Mid Size Business in 2026

Epicor Connected Process Control offers an intuitive software solution designed to create and manage digital work instructions while maintaining strict process control, effectively minimizing the chances of errors in operations. By integrating IoT devices, it captures comprehensive time studies and detailed process data, including images, at the task level, providing unprecedented real-time visibility and quality oversight. The eFlex system is versatile enough to accommodate countless product variations and thousands of components, catering to both component-based and model-based manufacturers alike. Furthermore, work instructions seamlessly connect to the Bill of Materials, guaranteeing that products are assembled correctly every time, even when modifications occur during production. This advanced system intelligently adapts to variations in models and components, ensuring that only the relevant work instructions for the current build at the station are presented, enhancing efficiency and accuracy throughout the manufacturing process. In this way, Epicor empowers manufacturers to maintain high standards of quality control while adapting to the dynamic nature of production demands.

Aizon: Intelligent GxP Manufacturing Aizon delivers an AI-powered platform that redefines how pharmaceutical and biotech manufacturers operate under GxP requirements. Our solutions empower teams to enhance efficiency, raise yields, and maintain the highest standards of product quality. - Aizon Execute — Intelligent Batch Record (iBR): Digitize production quickly to reduce manual errors, lower deviations, and accelerate the release of compliant batches. - Aizon Unify — Contextualized Intelligent Lakehouse: Connect and contextualize data from diverse sources to improve decision-making and achieve operational excellence. - Aizon Predict — GxP AI Industrialization: Use predictive AI models to fine-tune critical process parameters, increase Right-First-Time outcomes, and deliver higher manufacturing performance. Aizon enables manufacturers to move beyond traditional compliance and embrace true operational intelligence—learning from the past, acting decisively in the present, and innovating for the future.

Odoo is a highly customizable and open-source software solution that features a wide array of professionally crafted business applications. With its user-friendly database, Odoo addresses various business requirements, encompassing areas such as CRM, Sales, Projects, Manufacturing, Inventory, and Accounting. This versatile software is suitable for businesses of all sizes and budgets, making it an ideal choice for diverse company needs. The cohesive design of Odoo enhances operational efficiency and helps businesses save valuable time. Each module is designed to work harmoniously, providing a fluid experience as users navigate from one application to another. Automation capabilities allow users to streamline numerous tasks that would typically require manual entry across various systems. Odoo fosters collaboration among team members by consolidating all critical business functions onto a single platform, which ultimately enhances productivity and organization within the company. Furthermore, its adaptability ensures that businesses can continually evolve and tailor the system to their changing requirements.

Gain immediate insights into the performance of your manufacturing floor with the Shoplogix smart factory platform, which empowers manufacturers to enhance overall equipment effectiveness, cut down operational expenses, and boost profitability. This platform enables real-time visualization, integration, and action on production and machine performance, making it a trusted ally for manufacturers aiming to enhance efficiency in their factories. By leveraging analytics and real-time visual data, you can gain crucial insights that facilitate well-informed decision-making. Uncover untapped potential on the shop floor to accelerate your time-to-value significantly. Through a commitment to education, training, and data-centric decisions, you can foster a culture of continuous improvement within your organization. Make the Shoplogix Smart Factory Platform the cornerstone of your digital transformation journey, allowing you to thrive in the competitive i4.0 landscape. Furthermore, streamline data collection and interoperability with various manufacturing technologies by connecting to any device or piece of equipment, ensuring a seamless flow of information. Automate the monitoring, reporting, and analysis of machine states to effortlessly track production in real-time, enhancing your operational capabilities even further. In doing so, you position your manufacturing processes for sustained growth and innovation.

Epsilon3 is the leading AI-powered procedure and resource management tool designed for teams building, testing, and operating advanced products and systems. ✔ Save Time & Money Avoid costly delays, mistakes, and inefficiencies by automatically tracking procedures and resources. ✔ Prevent Failures Ensure the right step is completed at the right time with conditional logic and built-in revision control. ✔ Optimize Collaboration Real-time progress updates and role-based sign-offs keep your stakeholders on the same page. ✔ Continuously Improve Advanced data analytics and automated reporting enable rapid iteration and data-driven decisions. Epsilon3 is trusted by industry leaders like NASA, Blue Origin, Firefly Aerospace, Sierra Space, Redwire, Shift4, AeroVironment, Commonwealth Fusion Systems, and other commercial and government organizations.

Evocon is a cloud-based solution designed for monitoring production, assisting manufacturing firms in enhancing their operational efficiency. By automating and digitizing the process of gathering data from production machines, Evocon ensures that this information is seamlessly transferred to the cloud, allowing manufacturers to access it in real-time, whether they are on-site or working remotely. Furthermore, the platform visualizes this data in a user-friendly manner, making it actionable for users. This capability enables manufacturers to monitor downtime, minimize costs, and optimize their production equipment usage effectively. Additionally, it provides a foundation for informed decision-making, highlighting where to allocate resources and identifying which areas require the most focus for improvement. Through enhanced transparency, Evocon empowers organizations to chart a course based on their data insights. With over a decade of expertise in production monitoring, Evocon has been adopted in more than 50 countries and spans 14 diverse industries, all while offering support in 18 languages to cater to a global audience. This extensive reach underscores the platform's adaptability and effectiveness in various manufacturing environments.

Epicor Kinetic boasts a legacy of over five decades in manufacturing, establishing itself as a leader in delivering customized solutions on a global scale. At the heart of the Epicor strategy lies the cultivation of authentic, enduring partnerships, which ensures that its offerings are responsive to ever-evolving business requirements. Kinetic aims not only to meet existing needs but also to guide organizations towards the principles of Industry 4.0 and smarter manufacturing practices. This proactive stance is enhanced by the Epicor dedication to pioneering cloud solutions, characterized by unparalleled security, ease of use, and robust support. With an intuitive interface, Epicor Kinetic -- the global, AI-powered cloud ERP designed specifically for discrete, mixed-mode, and make-to-order manufacturers in the small and mid-market spaces -- empowers everyday users to transform business data into actionable insights and impactful reports that enhance productivity. By incorporating cutting-edge AI, machine learning, and Internet of Things technologies, the user experience provided by Kinetic enables a seamless transition to modern manufacturing methodologies. While primarily focused on cloud-based solutions, Epicor Kinetic also accommodates on-premises and hybrid deployment options, ensuring flexibility for various operational needs. Kinetic not only propels customer ambitions forward by offering tools to enhance productivity, growth, and operational efficiency but also solidifies Epicor's role as an indispensable ally for the most vital enterprises worldwide. Consequently, partnering with Epicor translates into a strategic advantage in navigating the complexities of today's manufacturing landscape.

Effectively overseeing the complex operations of enterprise manufacturers and distributors is vital for achieving business expansion. Infor M3 shines as a cloud-based ERP system specifically designed for the manufacturing and distribution sectors, leveraging advanced technologies to improve user interaction and provide comprehensive analytics across diverse industries, regions, and locations. In addition to Infor M3, the CloudSuite™ industry solutions deliver exceptional capabilities for various fields, including chemicals, distribution, equipment, fashion, food and beverage, and industrial manufacturing. To stay ahead of the competition, it is imperative to be agile and adaptive. The newest functionalities offer improved data-driven insights and streamlined workflows, enabling you to make quick, informed decisions and take necessary actions without delay. By adopting these innovations, businesses can significantly boost their operational efficiency and responsiveness, ensuring they thrive in the fast-paced market environment. This commitment to modernization not only fosters growth but also cultivates a culture of continuous improvement.

Fishbowl stands out as the top-selling software designed for managing warehouses and manufacturing processes. This software provides small and medium enterprises, including manufacturers, distributors, and service providers, with the capability to seamlessly incorporate sophisticated inventory functionalities into QuickBooks. Its features include tracking across multiple locations, managing bill of materials, facilitating billing and shipping, setting auto reorder points, and integrating with EDI shopping carts, merchant services, and various other business solutions. If you seek a cost-effective option for inventory management, Fishbowl is an outstanding choice. By utilizing its advanced technology, your business can enhance operational efficiency and achieve significant cost savings. Moreover, the user-friendly interface ensures that even those with limited tech experience can navigate and leverage its capabilities effectively.

Discover the perfect MRP solution designed specifically for small manufacturers! MRPeasy provides a cost-effective, intuitive, and cloud-based MRP system customized for the unique needs of small manufacturing enterprises. Easily convert customer orders into manufacturing orders, with the system handling the scheduling automatically. It efficiently manages inventory by booking items as needed, and can generate purchase orders if required. With real-time requirements in mind, MRPeasy offers both forward and backward scheduling options, while automated checks make certain that workers, workstations, and materials are readily available. Keep a detailed view of all your operations at any moment! Additionally, MRPeasy seamlessly integrates with leading accounting software like QuickBooks and Xero, as well as e-commerce platforms such as Shopify and WooCommerce, creating a comprehensive business management solution that fulfills all your operational needs. This integration not only enhances efficiency but also streamlines processes across various aspects of your business.

Simple, smart software for SME manufacturers. Flowlens delivers end-to-end business management software designed specifically to meet the needs of SME manufacturers. Use Flowlens to support your growth as you add customers, suppliers, stock and scale to your manufacturing business. With Flowlens, you can: • Centralize your business information in one secure, cloud-based system • Manage customers, suppliers, and inventory with complete visibility • Streamline production and capacity planning • Automatically identify stock shortages and create purchase orders • Handle multi-level BOMs and production routings with ease • Manage unlimited SKUs across your product lines • Maintain traceability and quality compliance • Control multi-site and multi-level stock operations • Deliver exceptional after-sales service with full product history • Integrate seamlessly with Xero, QuickBooks Online, and Sage 50  Optimise productivity. Whether you’re looking to replace paper and Excel based processes or older legacy systems, implementing Flowlens provides you with a proven pathway to boosting profitability and establishing data integration across your business functions.  Deliver financial visibility across your supply chain. Connect Flowlens with your accounting applications, and you’ll remove data double entry between functions and establish full online reporting visibility across all your operations.  Enhance stock control. Pinpoint your near and long term materials requirements through Flowlens capacity planning and multi-level BOM management.  Drive supplier management. Move your supplier management processes online with Flowlens. Simplify and streamline supplier negotiations and maximise your cost and quality position through Flowlens RFQ management functionality. Speak to our implementation staff today to agree an action plan that meets your goals for enhanced productivity, increased data integration and improved profitability.

The Katana Cloud Inventory platform offers an integrated view of your business, featuring real-time inventory and manufacturing oversight, batch tracking for comprehensive traceability, a dedicated Shop Floor App for complete control at the manufacturing level, an open API for seamless integrations, and an expanding network of channel partners. With real-time inventory insights, you can access current data to make well-informed decisions, effectively avoiding issues like stockouts and overstocking. This ensures you maintain full visibility of product locations, arrivals, and quantities, which is crucial for operational efficiency and accurate stock management. The platform also includes built-in purchase order management, allowing businesses to make data-driven purchasing choices based on specific material needs and reorder thresholds. Users can generate purchase orders directly through Katana and monitor potential delays to fulfill customer demands promptly. In terms of manufacturing operations management, you can establish your bill of materials and processes to enhance production scheduling, balance raw material and finished goods levels, and keep a close eye on manufacturing costs for a more efficient production workflow. Moreover, the omnichannel sales management feature consolidates all your B2B and B2C sales orders, enabling quick identification of available items for sale, thereby significantly streamlining your order fulfillment process and enhancing overall operational effectiveness. This comprehensive approach not only drives efficiency but also supports sustainable growth in your business.

Steelhead's innovative cloud-based solution enables you to digitize and enhance every aspect of your manufacturing workflow, specifically tailored for your metal finishing job shop. Our platform empowers operators to create quotes, manage work orders, and input product recipes with ease, while also allowing them to monitor part movements and generate packing slips or invoices seamlessly. In addition, operators can utilize our software to automatically produce reports and adjust job priorities efficiently. With a training period of just 10 minutes and implementation times as short as two weeks—significantly faster than the industry average of 18 months—we stand apart from conventional ERP or MES systems. Joining #TeamSteelhead means stepping into a realm of cutting-edge innovation and support designed to elevate your operations. You'll quickly discover the benefits of a streamlined manufacturing process that drives productivity and efficiency.

The PINpoint MES solution is comprised of the PINpoint V5 MMES Software along with specialized Targeted Services, both of which can greatly enhance production efficiency and product quality. This innovative solution effectively addresses and resolves issues related to production scheduling and sequencing permanently. It empowers your top operators by leveraging their vast knowledge and expertise in the field. Furthermore, it helps pinpoint inefficiencies within your processes and standard practices, allowing for their removal. By minimizing the need for constant "fire fighting," the solution promotes a culture of continuous improvement, which leads to a significant boost in operator engagement. These remarkable outcomes have been achieved by leading manufacturers that have integrated PINpoint MES solutions into their Industry 4.0 digital transformations. You can experience these benefits as well! Best of all, our solution starts delivering tangible results right from Day 1. Additionally, the implementation process is designed to be seamless, ensuring that your team can quickly adapt and thrive.

Since 1999, OmegaCube has been transforming business operations through innovative technology solutions. The company's flagship product, OmegaCube ERP, is a specialized enterprise resource management (ERP) system tailored specifically for the manufacturing and distribution sectors. This software effectively addresses the requirements of industries such as aerospace, automotive, metal fabrication, electronics, and medical devices. Designed to streamline workflows, it significantly enhances companies' operational efficiency. Furthermore, with our proprietary development studio, users can easily customize the software, develop their applications, and embed specific business rules with minimal coding effort. This flexibility allows employees to access the ERP system from any web browser or mobile device, regardless of their location. Additionally, the software can be deployed either on-premise or in the cloud, catering to diverse business needs. OmegaCube also provides the essential implementation expertise required for successful integration. Our reliable implementation strategy has empowered organizations of all sizes to achieve their strategic business objectives, fostering a culture of innovation and growth.

Tatsoft’s FrameworX is the complete, modern SCADA and IIoT platform for building, deploying, and scaling high-performance industrial applications. Designed for edge-to-enterprise use, it unifies real-time operations, data management, and AI integration under one consistent, open, and future-proof architecture. Built entirely on managed .NET code, FrameworX eliminates legacy constraints and delivers unmatched reliability, speed, and scalability for mission-critical environments. FrameworX includes all core modules from day one — Devices, Alarms, Historian, Reports, Security, Audit Trails, Scripting, and DevOps Tools — ensuring complete functionality without add-ons or hidden costs. Engineers can create sophisticated applications with built-in tools for real-time data modeling, event logging, trending, and analytics, along with 100+ native drivers for PLCs, DCSs, and industrial protocols including OPC UA, MQTT, SparkplugB, and Modbus. Need a custom driver? Tatsoft provides a toolkit for rapid protocol development. Develop once and deploy anywhere — Windows, Linux, Docker, Web, or Mobile — with zero client installation. FrameworX supports scripting in C#, VB.NET, and Python, enabling flexibility and fast integration with any industrial or enterprise system. Its built-in MQTT broker/client and Unified Namespace (UNS) capabilities connect OT and IT seamlessly, while WebAssembly deployment enables modern, plugin-free visualization across devices. Proven in over 5,000 global deployments, FrameworX powers critical operations in Oil & Gas, Steel, Transportation, Manufacturing, and Life Sciences. Its architecture supports 1M+ tags per second, 1,000+ concurrent clients, and startup times under 30 seconds. Combined with transparent licensing, unlimited scalability, and AI-ready design, FrameworX offers a unified platform that drives digital transformation across industries.

Q.Shop, which was formerly known as Quince Shop Floor Data Collector, is a specialized software solution tailored for the manufacturing industry, particularly for those involved in repair and overhaul operations. The processes associated with repair and overhaul can often be demanding and intricate. Q.Shop serves as a comprehensive data collection platform that consolidates shop floor inspection protocols, process manuals, work instructions, and machinery data into one cohesive system. This integration enhances traceability and fosters improved collaboration among technicians, supervisors, and managers alike. Additionally, Q.Shop provides a scheduling feature that organizes both jobs and employee shifts. By streamlining operational efficiency, it ensures that machine use and staff assignments are optimized. Operators are allocated to tasks based on their qualifications, expertise, and the certifications they hold. Furthermore, Q.Shop boosts overall productivity by delivering a scheduling solution that best fits the existing workforce, equipment availability, inventory levels, and sales demands, enabling businesses to operate more effectively. Ultimately, this software not only simplifies daily operations but also supports strategic decision-making in resource management.

Eyelit software offers a comprehensive and collaborative solution for manufacturing that enhances execution, streamlines supply chain management, and maximizes asset usage, while also incorporating tools for quality assurance. Known for its rapid deployment of "out of the box" features, Eyelit has established a solid reputation for meeting functional needs and achieving project objectives with little to no customization. At the heart of its offerings is the Eyelit MES, which serves as the foundational system and can be expanded with optional modules. These modules operate on a unified event-driven workflow engine that integrates the entire suite of products. Additionally, the configurable scenarios within the system assess real-time conditions to guide and manage processes effectively. Furthermore, the Eyelit Automation/Integration and Enterprise modules cater to a wide range of integration and automation requirements, supporting Industry 4.0 initiatives and ensuring seamless connectivity across both vertical and horizontal data value chains. This holistic approach positions Eyelit as a critical player in advancing modern manufacturing strategies.

Address issues as they arise with immediate insights from the production floor. Mingo Smart Factory stands out as the most user-friendly and quickly deployable manufacturing analytics system that scales effortlessly with your needs. This productivity platform offers a plug-and-play solution that integrates smoothly with your existing hardware setup. Mingo acts as a powerful manufacturing productivity and analytics tool that delivers real-time insights into the factory environment, helping to minimize downtime, enhance timely deliveries, and boost profitability for manufacturers. Mingo empowers production facilities with analytics and software tailored for manufacturing productivity, allowing businesses to start with small steps, envision grand goals, and accelerate their progress. Beyond being mere software, Mingo incorporates sensors designed to modernize older machinery, bringing them up to date with current technology. This digital toolkit is essential for reducing downtime, providing real-time visibility, replacing outdated Excel systems, unlocking capacity, and enhancing Overall Equipment Effectiveness (OEE). By utilizing Mingo, companies can decrease waste, improve operational efficiency, and propel their next stage of growth. All of this is achievable through a single, comprehensive platform, making it hard to believe you ever managed your factory without its remarkable capabilities. The ease of use and efficiency of Mingo can transform how you operate, paving the way for future innovations.

Our aim is to foster your company's advancement and achievement in the competitive landscape of manufacturing. MIE Solutions provides ERP software tailored for discrete manufacturing sectors, which encompass aerospace, automotive, metal fabrication, and electronics, among others. Clients can select from both cloud-based and on-premise solutions, along with the option of perpetual or SaaS licensing models. MIE Trak Pro is designed to accommodate multi-division operations, making it suitable for small startups as well as mid-sized firms in the discrete manufacturing arena. Our services extend to clients across the United States, Canada, Mexico, and New Zealand. We are genuinely invested in your business's growth and enhancements, reflecting our commitment to understanding your operations and production methodologies. The manufacturing sector is continuously changing, and we recognize this dynamic environment. By collaborating with us, you can enhance your growth potential while ensuring that you meet customer demands with timely deliveries and competitive pricing, all while maintaining profitability. We strive to be a partner in your success, helping you navigate challenges and seize opportunities in this evolving industry.

AMFG stands out as the premier automation solution designed specifically for manufacturers who operate with low volumes and a diverse mix of products. Its innovative approach streamlines processes, making it an essential tool for these specialized production environments.

Oracle NetSuite is the leading AI-powered Cloud ERP platform, empowering organizations to connect and optimize every aspect of their business. Built on the principle of a single source of truth, NetSuite eliminates silos by integrating ERP, financials, CRM, ecommerce, HCM, and analytics into one centralized cloud solution. Its AI capabilities go beyond automation by analyzing real-time business data to deliver predictive insights, personalized recommendations, and actionable forecasts. With more than 42,000 customers, NetSuite is trusted by businesses across industries and geographies for its scalability and reliability. Companies can leverage it to automate accounting, streamline financial close processes, and manage complex global operations with ease. Its CRM and HR features enhance customer engagement and workforce efficiency, while its professional services automation helps teams manage projects, billing, and resources more effectively. For commerce-driven organizations, NetSuite offers omnichannel commerce capabilities that unify online, in-store, and B2B sales, providing a seamless customer experience. The built-in analytics and reporting modules give leaders real-time visibility into performance across departments, enabling faster, data-driven decision-making. Oracle further strengthens NetSuite with consulting, support, and partner ecosystems, ensuring smooth deployment and ongoing optimization. By blending advanced AI, robust business functionality, and global scale, NetSuite sets the standard for modern enterprise resource planning.

Statii software serves as an ERP and MRP solution tailored for small to medium-sized manufacturing firms. It enables these companies to enhance their operations and remove obstacles within their manufacturing processes. Designed with simplicity and user-friendliness in mind, Statii is specifically aimed at the needs of SMBs. The platform provides an extensive array of tools aimed at boosting productivity while being cost-effective, thus allowing businesses to maintain their competitive edge and expand. Among its many features are capabilities for managing customer and supplier data, monitoring inquiry and quotation progress, and overseeing sales, work orders, and purchase orders. Additionally, these tools are designed to streamline various aspects of operations, ensuring that businesses can operate more efficiently and effectively.

Genius Solutions offers comprehensive enterprise resource planning (ERP) solutions, encompassing both software and implementation services tailored specifically for small to medium-sized custom manufacturing businesses. Genius ERP caters to manufacturers engaged in make-to-order, engineer-to-order, custom-to-order, and assemble-to-order processes. This unified system streamlines intricate manufacturing operations by facilitating precise estimating, product engineering, and effective inventory management. Additionally, it provides thorough oversight for managing field services, ensuring seamless operational efficiency and coordination. With such capabilities, manufacturers can optimize their workflows and enhance productivity significantly.

ProShop is an innovative, cloud-based management system that seamlessly integrates ERP and MES functionalities, specifically tailored for manufacturing firms operating in regulated industries. Developed right on the shop floor, ProShop stands out as a unique solution unlike any other available today. It excels in managing intricate manufacturing settings more effectively than competing products, offering unparalleled visibility into all facets of your manufacturing operations. Often referred to as a Digital Manufacturing Ecosystem, ProShop operates entirely paperlessly and merges the capabilities of ERP, MES, and QMS with various other software solutions. This comprehensive system is ideal for machine shops, fabricators, job shops, contract manufacturers, and other organizations in regulated fields that require stringent process management and demand precise, timely data to facilitate the most lucrative decision-making. By adopting ProShop, businesses can significantly enhance their operational efficiency and competitiveness in the market.