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What is ESMFold?

ESMFold exemplifies how artificial intelligence can provide us with groundbreaking tools to investigate the natural world, similar to how the microscope transformed our ability to see the intricate details of life. By leveraging AI, we can achieve new insights into the rich tapestry of biological diversity, thus deepening our understanding of life sciences. A considerable amount of AI research focuses on teaching machines to perceive the world in ways that parallel human cognition. However, the intricate language of proteins remains difficult for humans to interpret and has posed challenges for even the most sophisticated computational models. Despite these hurdles, AI has the potential to decode this complex language, thereby enhancing our understanding of biological mechanisms. Investigating AI's role in biology not only broadens our comprehension of life sciences but also illuminates the wider implications of artificial intelligence as a whole. Our research underscores the interconnected nature of various disciplines: the large language models that drive advancements in machine translation, natural language processing, speech recognition, and image generation also have the potential to uncover valuable insights into biological systems. This interdisciplinary strategy may lead to groundbreaking discoveries in both the fields of AI and biology, fostering collaboration that could yield transformative advancements. As we continue to explore these synergies, the future holds great promise for expanding our knowledge and capabilities in understanding life itself.

What is Claude Mythos 5?

Claude Mythos 5 is Anthropic’s restricted-access Mythos-class AI model built for trusted organizations that require the highest level of Claude capability. The model shares the same underlying architecture as Claude Fable 5, but is offered with certain safeguards removed for approved use cases and vetted users. Claude Mythos 5 is designed for advanced cybersecurity, software engineering, scientific discovery, long-context reasoning, and autonomous research workflows. It is initially deployed through Project Glasswing for cyberdefenders and critical infrastructure providers. The model is intended to help security teams analyze complex systems, support defensive cybersecurity work, and protect important software environments. Claude Mythos 5 also demonstrates major potential in life sciences, where it can assist with protein design, binding-site selection, bioinformatics workflows, and research hypothesis generation. Anthropic reports that the model can carry out extended technical tasks, recover from failures, and operate with a high degree of autonomy. Its capabilities in genomics include assembling large-scale single-cell datasets and designing custom machine learning approaches for biological research. Because these capabilities may be dual-use, Anthropic limits access through trusted programs and applies a 30-day retention policy for Mythos-class traffic. The model is priced at $10 per million input tokens and $50 per million output tokens. Claude Mythos 5 helps vetted organizations apply frontier AI to critical defense, infrastructure, and scientific problems while maintaining controlled access and oversight.

Media

Media

Integrations Supported

Anything
BLACKBOX AI
Bind AI
CSS
CSS
Claude
Claude Agent SDK
Claude for Life Sciences
Claw Code
GitHub Copilot
LaunchLemonade
Microsoft Foundry
OfoxAI
PhpStorm
PrivatClaw
PyCharm
Revise
Rust
Thread Deck
Verdent

Integrations Supported

Anything
BLACKBOX AI
Bind AI
CSS
CSS
Claude
Claude Agent SDK
Claude for Life Sciences
Claw Code
GitHub Copilot
LaunchLemonade
Microsoft Foundry
OfoxAI
PhpStorm
PrivatClaw
PyCharm
Revise
Rust
Thread Deck
Verdent

API Availability

Has API

API Availability

Has API

Pricing Information

Free
Free Trial Offered?
Free Version

Pricing Information

$10 per 1 million (input)
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

Meta

Date Founded

2004

Company Location

United States

Company Website

github.com/facebookresearch/esm

Company Facts

Organization Name

Anthropic

Date Founded

2023

Company Location

United States

Company Website

claude.ai

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