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What is FactSage?

FactSage is a comprehensive suite of software and databases designed for thermochemical analysis, developed through a partnership between Thermfact/CRCT, situated in Montreal, Canada, and GTT-Technologies, based in Aachen, Germany. Since its introduction in 2001, it has integrated the features of the FACT-Win/FAC*T and ChemSage/SOLGASMIX thermochemical tools, which are the result of over twenty years of collaborative research efforts. This software provides a variety of modules that facilitate information retrieval, database access, calculations, and data manipulation, effectively addressing the needs of a broad spectrum of pure substances and solution data. It caters to a wide range of users, including professionals in industry, governmental organizations, and academic institutions, spanning fields such as materials science, pyrometallurgy, hydrometallurgy, electrometallurgy, corrosion science, glass technology, combustion, ceramics, and geology. Users benefit from a wealth of thermodynamic data for numerous compounds and can access curated databases for hundreds of solutions, which include metals, oxides, slags, mattes, salts, and various aqueous solutions. Consequently, FactSage stands out as an essential resource for experts in search of dependable thermochemical information and analysis, making significant contributions to their research and development endeavors. Its ongoing updates and improvements ensure that it remains at the forefront of thermochemical software solutions.

What is Aurora Drug Discovery?

Aurora applies concepts from quantum mechanics and thermodynamics alongside an advanced continuous water model to evaluate solvation effects when determining the binding affinities of ligands. This approach is notably different from the conventional scoring functions that are commonly used to predict binding affinities. By incorporating both entropy and aqueous electrostatic elements into their calculations, the algorithms developed by Aurora provide notably more accurate and dependable estimates of binding free energies. The binding free energy, a key thermodynamic measure, fundamentally dictates the interaction between a ligand and a protein and is directly associated with the experimentally measurable inhibition constant (IC50). Various elements, such as electrostatic interactions, quantum phenomena, solvation dynamics, and the statistical behavior of molecules, all play a role in influencing this free energy (F). The non-additive characteristics of F arise primarily from two key components: the synergistic effects of electrostatic and solvation energies, as well as the entropy present in the system. Gaining a comprehensive understanding of these factors enhances the insight into the molecular interactions that are crucial for effective drug design and development.

Media

Media

Integrations Supported

Additional information not provided

Integrations Supported

Additional information not provided

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

FactSage

Date Founded

2001

Company Location

Canada

Company Website

factsage.com/introduction/

Company Facts

Organization Name

Aurora Fine Chemicals

Date Founded

1990

Company Location

United States

Company Website

aurorafinechemicals.com/drug-discovery-software.html

Categories and Features

Categories and Features

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