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What is Kaleido?

The microbiome is critically important in a range of diseases and health concerns. Kaleido is at the forefront of innovating a distinct approach to harness the microbiome's potential for effective patient treatments. The human microbiome consists of more than 30 trillion microbes, encompassing a wide variety of organisms such as bacteria, viruses, archaea, and fungi that reside both externally and internally within the body. In recent years, there has been an extraordinary increase in research examining how the microbiome affects human health, establishing connections to ailments like cardiovascular diseases, cancer, diabetes, Parkinson’s disease, and allergies. This complex network of microorganisms has been compared to a "newly discovered organ," underscoring its importance in human biology. Similar to how many human organs receive significant funding for therapies aimed at altering physiological processes, the microbiome stands as a largely uncharted domain in healthcare. By exploring this unexplored area, there is potential to reveal new therapeutic pathways that could significantly improve health outcomes for individuals. The quest to understand the microbiome better might be pivotal in revolutionizing modern medicine.

What is Gritstone?

At the core of our immunotherapy strategy is our deep understanding of antigens and neoantigens, especially when it comes to pinpointing which variations will be transcribed, translated, processed, and ultimately presented on cell surfaces through Human leukocyte antigen (HLA) molecules, making them identifiable to T cells. We utilize Gritstone EDGETM, an innovative platform that leverages machine learning to facilitate this process. The development of cancer immunotherapies that target tumor-specific neoantigens is particularly challenging due to the multitude of mutations present in tumors, where only a select few translate into true tumor-specific neoantigens. To address this intricate issue, we have engineered EDGE's advanced integrated neural network model, which has been trained on millions of data points sourced from a wide array of tumor and normal tissue samples derived from various patient backgrounds. This comprehensive training significantly boosts our ability to accurately identify neoantigens and enhances the overall effectiveness of our immunotherapy approaches, ultimately aiming to provide more targeted and effective treatments for patients. By continually refining our methods and expanding our databases, we strive to stay at the forefront of cancer immunotherapy advancements.

Media

Media

Integrations Supported

Azure Marketplace

Integrations Supported

API Availability

API Availability

Pricing Information

Pricing not provided

Pricing Information

Pricing not provided

Supported Platforms

SaaS

Supported Platforms

SaaS

Customer Service / Support

Standard Support
Web-Based Support

Customer Service / Support

Web-Based Support

Training Options

Documentation Hub
On-Site Training

Training Options

Not specified

Company Facts

Organization Name

Kaleido

Date Founded

2015

Company Location

United States

Company Website

kaleido.com/platform/

Company Facts

Organization Name

Gritstone bio

Date Founded

2015

Company Location

United States

Company Website

gritstonebio.com/scientific-platform/

Categories and Features

Drug Discovery

Not specified

Categories and Features

Drug Discovery

Not specified

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MIStar Reviews & Ratings

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