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What is PacBio?

Pacific Biosciences, commonly known as PacBio, stands at the forefront of life science technology, creating and producing cutting-edge sequencing solutions that empower scientists and clinical researchers to tackle complex genetic challenges. Their offerings span a wide array of research fields, including human germline sequencing, the study of plant and animal sciences, microbiology and infectious diseases, oncology, along with various emerging applications. The Revio system enhances accessibility and efficiency while maintaining the high-quality features of long reads, outstanding accuracy, and direct detection of methylation. In addition, the Onso system serves as a groundbreaking benchtop platform for short-read DNA sequencing, achieving remarkable accuracy through PacBio's innovative sequencing technique. Furthermore, the software tools designed for the Sequel II/IIe and Revio systems facilitate the setup and monitoring of long-read HiFi sequencing operations, allowing users to review performance metrics and effectively analyze, visualize, and annotate their sequencing data for deeper insights. Together, these systems and tools represent a significant advancement in the capabilities available to researchers in genomics.

What is Evo 2?

Evo 2 is an advanced genomic foundation model that excels in predicting and creating tasks associated with DNA, RNA, and proteins. Utilizing a sophisticated deep learning architecture, it models biological sequences with precision down to single-nucleotide accuracy, demonstrating remarkable scalability in both computational and memory resources as context length expands. The model has been trained on an impressive 40 billion parameters and can handle a context length of 1 megabase, analyzing an immense dataset of over 9 trillion nucleotides derived from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function predictions across a range of biological types, including DNA, RNA, and proteins, while also generating novel sequences that adhere to plausible genomic frameworks. Its robust capabilities have been highlighted in applications such as the design of efficient CRISPR systems and the identification of potentially disease-causing mutations in human genes. Additionally, Evo 2 is accessible to the public via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework, which significantly enhances its availability to researchers and developers. This integration not only broadens the model's reach but also represents a pivotal advancement in the fields of genomic modeling and analysis, paving the way for future innovations in biotechnology.

Media

Media

Integrations Supported

Integrations Supported

Evo Designer
GitHub
Hugging Face
NVIDIA BioNeMo

API Availability

Has API

API Availability

Pricing Information

Pricing not provided

Pricing Information

Pricing not provided

Supported Platforms

SaaS

Supported Platforms

SaaS

Customer Service / Support

Standard Support
Web-Based Support

Customer Service / Support

Web-Based Support

Training Options

Documentation Hub
Webinars

Training Options

Documentation Hub
On-Site Training

Company Facts

Organization Name

Pacific Biosciences (PacBio)

Date Founded

2004

Company Location

United States

Company Website

www.pacb.com/products-and-services/

Company Facts

Organization Name

Arc Institute

Company Location

United States

Company Website

arcinstitute.org/tools/evo

Categories and Features

LIMS

Not specified

Categories and Features

AI Models

Not specified

AI Science

Not specified

Bioinformatics

Not specified

Foundation Models

Not specified

Molecular Modeling

Not specified

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