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What is PacBio?

Pacific Biosciences, commonly known as PacBio, stands at the forefront of life science technology, creating and producing cutting-edge sequencing solutions that empower scientists and clinical researchers to tackle complex genetic challenges. Their offerings span a wide array of research fields, including human germline sequencing, the study of plant and animal sciences, microbiology and infectious diseases, oncology, along with various emerging applications. The Revio system enhances accessibility and efficiency while maintaining the high-quality features of long reads, outstanding accuracy, and direct detection of methylation. In addition, the Onso system serves as a groundbreaking benchtop platform for short-read DNA sequencing, achieving remarkable accuracy through PacBio's innovative sequencing technique. Furthermore, the software tools designed for the Sequel II/IIe and Revio systems facilitate the setup and monitoring of long-read HiFi sequencing operations, allowing users to review performance metrics and effectively analyze, visualize, and annotate their sequencing data for deeper insights. Together, these systems and tools represent a significant advancement in the capabilities available to researchers in genomics.

What is Genome Analysis Toolkit (GATK)?

Developed by the Data Sciences Platform at the Broad Institute, this all-encompassing toolkit offers a broad spectrum of features that focus largely on variant discovery and genotyping. It boasts a powerful processing engine along with high-performance computing capabilities, making it suitable for handling projects of any size. The GATK is recognized as the gold standard for identifying SNPs and indels in germline DNA as well as RNA sequencing data. Its functionalities are expanding to include detection of somatic short variants, as well as tackling copy number variations (CNV) and structural variations (SV). In addition to the primary variant callers, the GATK features a variety of utilities designed for performing related tasks, such as processing and ensuring the quality of high-throughput sequencing data, and it is complemented by the renowned Picard toolkit. Initially tailored for exome and whole genome data produced by Illumina sequencing technologies, these tools exhibit enough flexibility to adapt to various other sequencing technologies and study designs. As the field of genomics continues to advance, the GATK's versatility guarantees its ongoing relevance in a wide range of genomic research projects, ensuring that it remains a pivotal resource for scientists exploring genetic variations.

Media

Media

Integrations Supported

Integrations Supported

Docker

API Availability

Has API

API Availability

Pricing Information

Pricing not provided

Pricing Information

Free
Free Version

Supported Platforms

SaaS

Supported Platforms

SaaS
Windows
Mac
Linux

Customer Service / Support

Standard Support
Web-Based Support

Customer Service / Support

Web-Based Support

Training Options

Documentation Hub
Webinars

Training Options

Documentation Hub
Webinars

Company Facts

Organization Name

Pacific Biosciences (PacBio)

Date Founded

2004

Company Location

United States

Company Website

www.pacb.com/products-and-services/

Company Facts

Organization Name

Broad Institute

Company Location

United States

Company Website

gatk.broadinstitute.org/hc/

Categories and Features

LIMS

Not specified

Categories and Features

Bioinformatics

Not specified

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