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What is VeraChem?

Established in 2000, VeraChem LLC is dedicated to advancing the realms of computer-aided drug discovery and molecular design by developing sophisticated computational chemistry methods that integrate groundbreaking scientific principles with real-world research applications. A fundamental component of the company’s approach to product innovation is providing high-performance software solutions paired with comprehensive user assistance. VeraChem’s software currently boasts capabilities such as predicting protein-ligand and host-guest binding affinities, executing rapid and accurate computations of partial atomic charges for drug-like substances, and calculating energies and forces using popular empirical force fields. Furthermore, the software includes features for the automatic generation of alternative resonance forms for drug-like molecules, an efficient conformational search powered by the Tork algorithm, and the automated detection of topological and three-dimensional molecular symmetries. The modular design of VeraChem’s software packages facilitates adaptability and flexibility, allowing users to tailor these tools to meet a variety of research demands effectively. By providing such versatile resources, VeraChem empowers researchers to enhance their investigative efforts in drug discovery.

What is ESMC?

ESMC marks the latest innovation in the ESM series of protein language models, advancing the understanding of representation learning in protein biology. By training on an enormous dataset of billions of evolutionary sequences, it effectively captures representations that provide insights into the mechanistic aspects of protein structure and function. Utilizing a transformer architecture, the model prioritizes sequences as its main input and is trained on a dataset that includes up to 6 billion proteins. ESMC is designed for a range of applications within protein science, including structure prediction, functional annotation, protein design, and the investigation of evolutionary relationships among proteins. Furthermore, it has the ability to generate new proteins from partial sequences, structures, or specific functional requirements, which allows researchers to explore novel possibilities in protein design and biological research. The model is readily accessible through the Biohub Platform, enabling users to interact with it via an API and the ESM Python package, which offers quickstart resources for installation, API key generation, and connection to the platform, thus ensuring a user-friendly experience. This ease of access not only promotes wider participation in protein research but also fosters collaborative efforts across the scientific community, ultimately driving further advancements in the field. With its capabilities, ESMC opens new doors for innovation and discovery in protein science.

Media

Media

Integrations Supported

Biohub
Python

Integrations Supported

Biohub
Python

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Pricing Information

Free
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

VeraChem

Company Location

United States

Company Website

www.verachem.com/small-molecules/

Company Facts

Organization Name

Biohub

Date Founded

2016

Company Location

United States

Company Website

biohub.ai/models/esmc

Categories and Features

Categories and Features

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