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What is Working Model 2D?

Working Model is recognized as the leading motion simulation software in the world. Utilizing powerful analytical tools allows you to validate designs effectively. The swift "run-analyze-refine" method empowers you to make adjustments to your designs before producing any physical prototypes, thereby greatly reducing the necessity for them. You retain complete control over the simulation environment throughout the process. Create, run, and improve simulations quickly with a library of pre-built objects and constraints at your fingertips. You can start, stop, reset, step through, or pause the simulation as needed. Assess your latest design by analyzing multiple metrics such as force, torque, and acceleration on every component. Results can be displayed as vectors or numerical values, configurable in either English or metric units. Moreover, the capability to import your 2D CAD drawings in DXF format is seamless. Data can be entered from equations, sliders, and DDE links compatible with both MATLAB and Excel. You can build bodies and specify their mass properties, initial velocity, and electrostatic charge, among other attributes. Additionally, you have the flexibility to run or adjust scripts to improve simulations, document models, and a variety of other tasks. You can also craft engaging presentations by adding images, which enhances the overall presentation of your work. This all-encompassing tool revolutionizes how designers and engineers tackle motion simulation challenges, making the process more efficient and impactful. Ultimately, it fosters creativity and innovation in design practices across various industries.

What is Aurora Drug Discovery?

Aurora applies concepts from quantum mechanics and thermodynamics alongside an advanced continuous water model to evaluate solvation effects when determining the binding affinities of ligands. This approach is notably different from the conventional scoring functions that are commonly used to predict binding affinities. By incorporating both entropy and aqueous electrostatic elements into their calculations, the algorithms developed by Aurora provide notably more accurate and dependable estimates of binding free energies. The binding free energy, a key thermodynamic measure, fundamentally dictates the interaction between a ligand and a protein and is directly associated with the experimentally measurable inhibition constant (IC50). Various elements, such as electrostatic interactions, quantum phenomena, solvation dynamics, and the statistical behavior of molecules, all play a role in influencing this free energy (F). The non-additive characteristics of F arise primarily from two key components: the synergistic effects of electrostatic and solvation energies, as well as the entropy present in the system. Gaining a comprehensive understanding of these factors enhances the insight into the molecular interactions that are crucial for effective drug design and development.

Media

Media

Integrations Supported

Additional information not provided

Integrations Supported

Additional information not provided

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

Design Simulation Technologies

Date Founded

2005

Company Location

United States

Company Website

www.design-simulation.com

Company Facts

Organization Name

Aurora Fine Chemicals

Date Founded

1990

Company Location

United States

Company Website

aurorafinechemicals.com/drug-discovery-software.html

Categories and Features

Simulation

1D Simulation
3D Modeling
3D Simulation
Agent-Based Modeling
Continuous Modeling
Design Analysis
Direct Manipulation
Discrete Event Modeling
Dynamic Modeling
Graphical Modeling
Industry Specific Database
Monte Carlo Simulation
Motion Modeling
Presentation Tools
Stochastic Modeling
Turbulence Modeling

Categories and Features

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