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What is ESMFold?

ESMFold exemplifies how artificial intelligence can provide us with groundbreaking tools to investigate the natural world, similar to how the microscope transformed our ability to see the intricate details of life. By leveraging AI, we can achieve new insights into the rich tapestry of biological diversity, thus deepening our understanding of life sciences. A considerable amount of AI research focuses on teaching machines to perceive the world in ways that parallel human cognition. However, the intricate language of proteins remains difficult for humans to interpret and has posed challenges for even the most sophisticated computational models. Despite these hurdles, AI has the potential to decode this complex language, thereby enhancing our understanding of biological mechanisms. Investigating AI's role in biology not only broadens our comprehension of life sciences but also illuminates the wider implications of artificial intelligence as a whole. Our research underscores the interconnected nature of various disciplines: the large language models that drive advancements in machine translation, natural language processing, speech recognition, and image generation also have the potential to uncover valuable insights into biological systems. This interdisciplinary strategy may lead to groundbreaking discoveries in both the fields of AI and biology, fostering collaboration that could yield transformative advancements. As we continue to explore these synergies, the future holds great promise for expanding our knowledge and capabilities in understanding life itself.

What is ESMC?

ESMC marks the latest innovation in the ESM series of protein language models, advancing the understanding of representation learning in protein biology. By training on an enormous dataset of billions of evolutionary sequences, it effectively captures representations that provide insights into the mechanistic aspects of protein structure and function. Utilizing a transformer architecture, the model prioritizes sequences as its main input and is trained on a dataset that includes up to 6 billion proteins. ESMC is designed for a range of applications within protein science, including structure prediction, functional annotation, protein design, and the investigation of evolutionary relationships among proteins. Furthermore, it has the ability to generate new proteins from partial sequences, structures, or specific functional requirements, which allows researchers to explore novel possibilities in protein design and biological research. The model is readily accessible through the Biohub Platform, enabling users to interact with it via an API and the ESM Python package, which offers quickstart resources for installation, API key generation, and connection to the platform, thus ensuring a user-friendly experience. This ease of access not only promotes wider participation in protein research but also fosters collaborative efforts across the scientific community, ultimately driving further advancements in the field. With its capabilities, ESMC opens new doors for innovation and discovery in protein science.

Media

Media

Integrations Supported

Biohub
Python

Integrations Supported

Biohub
Python

API Availability

Has API

API Availability

Has API

Pricing Information

Free
Free Trial Offered?
Free Version

Pricing Information

Free
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

Meta

Date Founded

2004

Company Location

United States

Company Website

github.com/facebookresearch/esm

Company Facts

Organization Name

Biohub

Date Founded

2016

Company Location

United States

Company Website

biohub.ai/models/esmc

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