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What is Folklore Clinical Variant Interpretation?

Helena Bioinformatics develops Folklore as its flagship platform for professional review of genomic variants. Laboratories and research teams can examine classification, supporting scientific evidence, phenotype, inheritance and prioritisation together in a traceable case. Supported work includes panels, exomes and genomes, with framework-specific handling of nuclear, mitochondrial and structural or copy-number variants. Folklore also offers a separate public MCP interface for read-only evidence and literature discovery. This interface does not accept patient data or private case files. Folklore is research-use-only and not CE-marked. A qualified specialist remains responsible for final interpretation; the product does not diagnose or recommend treatment.

What is AlphaGenome 2?

AlphaGenome 2 represents a cutting-edge AI research platform designed to investigate how DNA sequences influence gene regulation and related molecular processes. By entering specific DNA sequences, the framework can predict various molecular traits, thus aiding scientists in their exploration of gene expression patterns, regulatory functions, splicing, chromatin accessibility, and other genomic factors. Tailored for researchers aiming to unravel gene functionalities, the consequences of genetic variations, and disease biology, it serves both academic institutions and noncommercial research organizations. The platform is conveniently accessible through an online API, which offers developer tools that streamline the sequence submission process and facilitate the retrieval of predictions that are essential for computational studies. This empowers researchers to effectively prioritize their hypotheses and shape their upcoming experimental designs. It is essential to highlight that AlphaGenome 2 is exclusively intended for research purposes and has not been validated or authorized for any clinical or diagnostic applications, emphasizing the need for users to understand its intended use and limitations. This focus on research underscores the necessity of responsible practices in scientific exploration, ensuring that users remain cognizant of the framework's capabilities and constraints. Researchers utilizing this tool can significantly enhance their understanding of complex genomic interactions.

Media

Media

No images available

Integrations Supported

Additional information not provided

Integrations Supported

Additional information not provided

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided

Pricing Information

The AlphaGenome API is free of charge for noncommercial use. Commercial research access is in private preview.
Free Version

Supported Platforms

SaaS

Supported Platforms

SaaS

Customer Service / Support

Web-Based Support

Customer Service / Support

Not specified

Training Options

Documentation Hub

Training Options

Documentation Hub

Company Facts

Organization Name

Helena Bioinformatics

Company Location

Bulgaria

Company Website

folklore.helena.bio

Company Facts

Organization Name

Google DeepMind

Date Founded

2010

Company Location

United Kingdom

Company Website

deepmind.google/science/alphagenome/

Categories and Features

Categories and Features

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