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What is HyperProtein?

Hypercube, Inc. has launched HyperProtein, a cutting-edge tool focused on the computational evaluation of protein sequences. This groundbreaking software goes beyond merely assessing one-dimensional sequences, as it also investigates the resulting three-dimensional structures of proteins. A significant feature of HyperProtein is its in-depth examination of the complex connections between a protein's sequence and its structural configuration. Unlike software that is limited to specific tasks such as sequence alignment, HyperProtein unifies a broad spectrum of Bioinformatics and Molecular Modeling tools, offering a holistic approach to the study that starts with a protein's sequence. By merging these various resources, HyperProtein seeks to deepen the understanding of protein functions and interactions at a molecular scale, thus serving as an essential asset for researchers in the scientific community. As a result, it represents a significant advancement in the tools available for protein analysis and modeling.

What is ESMFold2?

Building upon its predecessor, ESMFold, ESMFold2 sets a new standard in the realm of single-sequence structure prediction while also enabling the design of novel functional proteins by delving into the latent space of the ESMC model. This sophisticated model can accurately predict high-resolution, all-atom 3D structures of biomolecular complexes directly from amino acid sequences and incorporates multiple sequence alignments to enhance accuracy for challenging targets. Designed to predict structures using both sequence and structural modalities, it utilizes ESM representations that power a sequence of looped folding layers, while a diffusion model converts pairwise representations into atomic-resolution results. ESMFold2 stands out in its ability to forecast protein structures from amino acid sequences, providing comprehensive structural information, including exact all-atom coordinates for backbone and side chains, as well as confidence metrics and optional distogram predictions for thorough structural analysis. In addition, its groundbreaking methodology deepens the understanding of protein folding dynamics and their functional implications, positioning it as an indispensable tool for researchers engaging in this area of study. Ultimately, ESMFold2 not only advances structural biology but also opens new avenues for the development of protein-based applications.

Media

Media

Integrations Supported

Biohub
Python

Integrations Supported

Biohub
Python

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Pricing Information

Free
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

Hypercube

Company Website

www.hypercubeusa.com

Company Facts

Organization Name

Biohub

Date Founded

2016

Company Location

United States

Company Website

biohub.ai/models/esmfold2

Categories and Features

Chemical

Certificates of Analysis
Chemical Process Simulation
Computer-Assisted Structure Elucidation (CASE)
ISO Management
Inventory Management
Particle Tracking
Reporting & Statistics
Samples Tracking
Traceability
Uncertainty Analysis

Categories and Features

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