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What is Biohub?

Biohub is a user-friendly platform focused on enhancing the comprehension of protein biology. It provides access to the ESM model family, which features ESMC, ESMFold2, and ESM3, as well as interactive tools and resources specifically designed for developers engaged in protein science research. ESMC is recognized as a state-of-the-art protein language model, carefully trained on extensive evolutionary sequence data, enabling it to generate representations that clarify fundamental mechanisms related to protein structure and function. This model supports a variety of applications, including functional analysis, structural predictions, protein design, and exploring evolutionary relationships among diverse proteins. In addition, ESMFold2 excels in predicting high-resolution, all-atom 3D structures of biomolecular complexes from sequences, and it allows for the incorporation of multiple sequence alignments to enhance accuracy for challenging targets. Furthermore, ESM3 adopts a comprehensive methodology by concurrently modeling sequence, structure, and function, which facilitates the innovative design of new proteins through a synergistic approach. This remarkable combination of tools and models equips researchers with the means to push the boundaries of protein science, fostering groundbreaking discoveries that could transform the field. Overall, Biohub's offerings represent a significant leap forward in our ability to manipulate and understand protein interactions and functionalities.

What is NVIDIA BioNeMo?

BioNeMo is a cloud-based platform designed for drug discovery that harnesses artificial intelligence and employs NVIDIA NeMo Megatron to enable the training and deployment of large biomolecular transformer models at an impressive scale. This service provides users with access to pre-trained large language models (LLMs) and supports multiple file formats pertinent to proteins, DNA, RNA, and chemistry, while also offering data loaders for SMILES to represent molecular structures and FASTA for sequences of amino acids and nucleotides. In addition, users have the flexibility to download the BioNeMo framework for local execution on their own machines. Among the notable models available are ESM-1, which is based on Meta AI’s state-of-the-art ESM-1b, and ProtT5, both fine-tuned transformer models aimed at protein language tasks that assist in generating learned embeddings for predicting protein structures and properties. Furthermore, the platform will incorporate OpenFold, an innovative deep learning model specifically focused on forecasting the 3D structures of new protein sequences, which significantly boosts its capabilities in biomolecular exploration. Overall, this extensive array of tools establishes BioNeMo as an invaluable asset for researchers navigating the complexities of drug discovery in modern science. As such, BioNeMo not only streamlines research processes but also empowers scientists to make significant advancements in the field.

Media

Media

Integrations Supported

ESMC
ESMFold2

Integrations Supported

Evo 2
NVIDIA AI Foundations
NVIDIA Clara
NVIDIA NeMo Megatron

API Availability

Has API

API Availability

Pricing Information

Pricing not provided

Pricing Information

Pricing not provided

Supported Platforms

SaaS

Supported Platforms

SaaS

Customer Service / Support

Web-Based Support

Customer Service / Support

Standard Support
Web-Based Support

Training Options

Documentation Hub
Online Training

Training Options

Documentation Hub
Webinars

Company Facts

Organization Name

Biohub

Date Founded

2016

Company Location

United States

Company Website

biohub.ai/

Company Facts

Organization Name

NVIDIA

Date Founded

1993

Company Location

United States

Company Website

www.nvidia.com/en-us/gpu-cloud/bionemo/

Categories and Features

AI Science

Not specified

Bioinformatics

Not specified

Categories and Features

AI Science

Not specified

Drug Discovery

Not specified

Healthcare AI

Not specified

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