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What is Loupe Browser?

Loupe Browser distinguishes itself as an effective visualization platform, equipped with intuitive features that are crucial for exploring and analyzing datasets from 10x Genomics Chromium and Visium. Furthermore, the LoupeR package streamlines the process of converting Seurat objects into formats that are compatible with Loupe Browser. The interactive capabilities of Loupe Browser are well-demonstrated through its application to a lung squamous cell carcinoma dataset. A key aspect of the user interface is the view panel, which displays individual points, each corresponding to a cell barcode, across various projections. Typically, each point represents the barcode of a single cell, facilitating detailed analysis. The default projection is a t-SNE plot generated by the cell ranger pipeline, but users also have access to other visualization options. They can easily drag the mouse over the cells to reposition the plot and utilize the mouse wheel or trackpad for zooming in or out. Additionally, when the mouse hovers over the plot, cluster labels appear, which is especially advantageous for analyzing datasets with many precomputed clusters. This feature significantly enriches the analytical process, allowing for easier identification and interpretation of intricate data patterns. With its user-centric design and functionality, Loupe Browser empowers researchers to gain deeper insights from their genomic data.

What is Evo 2?

Evo 2 is an advanced genomic foundation model that excels in predicting and creating tasks associated with DNA, RNA, and proteins. Utilizing a sophisticated deep learning architecture, it models biological sequences with precision down to single-nucleotide accuracy, demonstrating remarkable scalability in both computational and memory resources as context length expands. The model has been trained on an impressive 40 billion parameters and can handle a context length of 1 megabase, analyzing an immense dataset of over 9 trillion nucleotides derived from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function predictions across a range of biological types, including DNA, RNA, and proteins, while also generating novel sequences that adhere to plausible genomic frameworks. Its robust capabilities have been highlighted in applications such as the design of efficient CRISPR systems and the identification of potentially disease-causing mutations in human genes. Additionally, Evo 2 is accessible to the public via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework, which significantly enhances its availability to researchers and developers. This integration not only broadens the model's reach but also represents a pivotal advancement in the fields of genomic modeling and analysis, paving the way for future innovations in biotechnology.

Media

Media

Integrations Supported

Evo Designer
GitHub
Hugging Face
NVIDIA BioNeMo

Integrations Supported

Evo Designer
GitHub
Hugging Face
NVIDIA BioNeMo

API Availability

Has API

API Availability

Has API

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Pricing Information

Pricing not provided.
Free Trial Offered?
Free Version

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Supported Platforms

SaaS
Android
iPhone
iPad
Windows
Mac
On-Prem
Chromebook
Linux

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Customer Service / Support

Standard Support
24 Hour Support
Web-Based Support

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

10x Genomics

Date Founded

2012

Company Location

United States

Company Website

www.10xgenomics.com/support/software/loupe-browser/latest

Company Facts

Organization Name

Arc Institute

Company Location

United States

Company Website

arcinstitute.org/tools/evo

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