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What is Loupe Browser?

Loupe Browser distinguishes itself as an effective visualization platform, equipped with intuitive features that are crucial for exploring and analyzing datasets from 10x Genomics Chromium and Visium. Furthermore, the LoupeR package streamlines the process of converting Seurat objects into formats that are compatible with Loupe Browser. The interactive capabilities of Loupe Browser are well-demonstrated through its application to a lung squamous cell carcinoma dataset. A key aspect of the user interface is the view panel, which displays individual points, each corresponding to a cell barcode, across various projections. Typically, each point represents the barcode of a single cell, facilitating detailed analysis. The default projection is a t-SNE plot generated by the cell ranger pipeline, but users also have access to other visualization options. They can easily drag the mouse over the cells to reposition the plot and utilize the mouse wheel or trackpad for zooming in or out. Additionally, when the mouse hovers over the plot, cluster labels appear, which is especially advantageous for analyzing datasets with many precomputed clusters. This feature significantly enriches the analytical process, allowing for easier identification and interpretation of intricate data patterns. With its user-centric design and functionality, Loupe Browser empowers researchers to gain deeper insights from their genomic data.

What is Illumina DRAGEN Secondary Analysis?

The DRAGEN Secondary Analysis system from Illumina provides accurate, comprehensive, and exceptionally efficient processing of next-generation sequencing data. By leveraging a graph reference genome in combination with machine learning methodologies, it achieves outstanding precision. With a highly streamlined workflow, it can fully analyze a 34x whole human genome in roughly 30 minutes when operated on the DRAGEN server v4. Furthermore, it optimizes this process by reducing FASTQ file sizes by as much as five times. This system is proficient in handling diverse types of NGS data, such as whole genomes, exomes, methylomes, and transcriptomes. It has been designed to work seamlessly with the user's chosen platform and can scale to accommodate various needs. DRAGEN analysis is consistently recognized as a frontrunner in accuracy for detecting both germline and somatic variants, supported by its strong performance in industry competitions hosted by precisionFDA. This sophisticated analytical tool enables laboratories of all sizes and specialties to fully leverage their genomic datasets. Additionally, the integration of highly adaptable field-programmable gate array (FPGA) technology allows DRAGEN to implement hardware-accelerated genomic analysis algorithms, significantly improving its efficiency. These advancements firmly establish DRAGEN as an essential asset in the rapidly advancing realm of genomics, enabling researchers to push the boundaries of scientific discovery.

Media

Media

Integrations Supported

Integrations Supported

Amazon Web Services (AWS)
BaseSpace Sequence Hub
Correlation Engine
Emedgene
Illumina Connected Analytics

API Availability

API Availability

Has API

Pricing Information

Pricing not provided

Pricing Information

Pricing not provided
Free Trial Offered?

Supported Platforms

Windows
Mac
Linux

Supported Platforms

SaaS
On-Prem

Customer Service / Support

Standard Support
Web-Based Support

Customer Service / Support

Standard Support
Web-Based Support

Training Options

Documentation Hub
On-Site Training

Training Options

Documentation Hub
Webinars
Online Training
On-Site Training

Company Facts

Organization Name

10x Genomics

Date Founded

2012

Company Location

United States

Company Website

www.10xgenomics.com/support/software/loupe-browser/latest

Company Facts

Organization Name

Illumina

Company Location

United States

Company Website

www.illumina.com/products/by-type/informatics-products/dragen-secondary-analysis.html

Categories and Features

Bioinformatics

Not specified

Categories and Features

Bioinformatics

Not specified

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